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Apoptosis
Apoptosis
Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells
Immunohistochemistry / Enzyme Inhibitors / Apoptosis / Humans / Protein Kinases / Mice / Animals / Male / Caspase / Carcinogenesis / Plant extracts / Momordica / Cell Proliferation / Cell Survival / Enzyme Linked Immunosorbent Assay / Mice / Animals / Male / Caspase / Carcinogenesis / Plant extracts / Momordica / Cell Proliferation / Cell Survival / Enzyme Linked Immunosorbent Assay
Dental Abnormalities in a Mouse Model for Craniometaphyseal Dysplasia
Dentistry / Apoptosis / Mice / Animals / Osteoclasts / Dental / Phenotype / Tooth Root / Incisor / Tooth Eruption / Cell Shape / Bone remodeling / DENTAL CEMENTUM / Cell Proliferation / Somatic Cell Count / Extracellular Matrix Proteins / Dental / Phenotype / Tooth Root / Incisor / Tooth Eruption / Cell Shape / Bone remodeling / DENTAL CEMENTUM / Cell Proliferation / Somatic Cell Count / Extracellular Matrix Proteins
Leukocyte Elastase Induces Lung Epithelial Apoptosis via a PAR-1–, NF-κB–, and p53-Dependent Pathway
Mitochondria / Apoptosis / Signal Transduction / Cell line / Humans / Permeability / NF-kappa B / American / Phosphorylation / Lung / Caspase / Epithelial cells / Permeability / NF-kappa B / American / Phosphorylation / Lung / Caspase / Epithelial cells
Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects
Membrane Proteins / Endoplasmic Reticulum Stress / Morphogenesis / Apoptosis / Molecular chaperones / Congenital Heart Defects / Reactive Oxygen Species / Animals / Endoplasmic Reticulum / Calcium Signaling / Embryonic Stem Cells / Phenotype / Time Factors / Zebrafish / Congenital Heart Defects / Reactive Oxygen Species / Animals / Endoplasmic Reticulum / Calcium Signaling / Embryonic Stem Cells / Phenotype / Time Factors / Zebrafish
An Animal Model of Autoimmune Emphysema
Apoptosis / Autoimmune diseases / Endothelial Cells / Animals / Male / American / Animal Model / Rats / Cell Proliferation / Sensitivity and Specificity / Reference Values / Enzyme Linked Immunosorbent Assay / Autoantibodies / American / Animal Model / Rats / Cell Proliferation / Sensitivity and Specificity / Reference Values / Enzyme Linked Immunosorbent Assay / Autoantibodies
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3
Organic Chemistry / Apoptosis / Cell line / Stroke / Escherichia coli / Signal Transduction Pathway Models / Caspase / Protease Inhibitors / Bioorganic and medicinal Chemistry / Structure activity Relationship / Signal Transduction Pathway Models / Caspase / Protease Inhibitors / Bioorganic and medicinal Chemistry / Structure activity Relationship
Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo
Kinetics / Macrophages / Stem Cell / Transcription Factors / Apoptosis / Gene expression / Multidisciplinary / Hematopoietic Stem Cells / Erythropoietin / Cell Differentiation / Mice / Animals / Acetylcholinesterase / Bone marrow / Antisense Oligonucleotide Drugs / Cell Proliferation / Base Sequence / DNA binding proteins / Bone Marrow Cells / Interleukin / Enzyme Induction / Gene expression / Multidisciplinary / Hematopoietic Stem Cells / Erythropoietin / Cell Differentiation / Mice / Animals / Acetylcholinesterase / Bone marrow / Antisense Oligonucleotide Drugs / Cell Proliferation / Base Sequence / DNA binding proteins / Bone Marrow Cells / Interleukin / Enzyme Induction
Caspase-3 Activity as a Prognostic Factor in Colorectal Carcinoma
Genetics / Immunohistochemistry / Apoptosis / Colorectal cancer / Caspases / Humans / Wnt Signaling / Risk factors / Clinical Sciences / Caspase / Prognosis / Protein Expression / Risk Factors / Humans / Wnt Signaling / Risk factors / Clinical Sciences / Caspase / Prognosis / Protein Expression / Risk Factors
Cytotoxic effect of magnetic iron oxide nanoparticles synthesized via seaweed aqueous extract
Water / Toxicology / Cancer / Nanomedicine / Treatment Outcome / Cancer Biology / Nanotechnology / Apoptosis / Humans / Nanoscience / Seaweed / Plant extracts / HeLa cells / Green Synthesis / Cell Survival / Antineoplastic Agents / Magnetite Nanoparticles / Cancer Biology / Nanotechnology / Apoptosis / Humans / Nanoscience / Seaweed / Plant extracts / HeLa cells / Green Synthesis / Cell Survival / Antineoplastic Agents / Magnetite Nanoparticles
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a New Mitochondrial Benzodiazepine-Receptor Ligand, Induces Apoptosis in C6 glioma Cells
Mitochondria / DNA damage / Apoptosis / Caspases / Glioma / Animals / Caspase / Rats / Time Factors / Antineoplastic Agents / Ligands / Biochemistry and cell biology / Animals / Caspase / Rats / Time Factors / Antineoplastic Agents / Ligands / Biochemistry and cell biology
Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors
Genetics / Caenorhabditis elegans / Enzyme Inhibitors / Apoptosis / Gene expression / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences
In Vitro Acute Exposure to DEHP Affects Oocyte Meiotic Maturation, Energy and Oxidative Stress Parameters in a Large Animal Model
Oxidative Stress / Mitochondria / Apoptosis / Multidisciplinary / Oogenesis / Low Dose / Meiosis / Reactive Oxygen Species / Female / Animals / Animal Model / Horses / Plasticizers / Superoxide Dismutase / PLoS one / Behavioral Animal Models / Oocyte Maturation / Ovarian Follicle / N-Acetylcysteine / Oocytes / Embryos / Cytoplasm / Oxidation-Reduction / Low Dose / Meiosis / Reactive Oxygen Species / Female / Animals / Animal Model / Horses / Plasticizers / Superoxide Dismutase / PLoS one / Behavioral Animal Models / Oocyte Maturation / Ovarian Follicle / N-Acetylcysteine / Oocytes / Embryos / Cytoplasm / Oxidation-Reduction
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy
Mitochondria / Autophagy / Apoptosis / Western blotting / Humans / Reactive Oxygen Species / Mice / Animals / Electron Transport / Biological markers / Cell Proliferation / Human Fibroblasts / Cell Survival / Syndrome / Coenzyme Q / Biochemistry and cell biology / Gene Expression Regulation / Reactive Oxygen Species / Mice / Animals / Electron Transport / Biological markers / Cell Proliferation / Human Fibroblasts / Cell Survival / Syndrome / Coenzyme Q / Biochemistry and cell biology / Gene Expression Regulation
Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis
Oxidative Stress / Mitochondria / Apoptosis / Cardiovascular disease / Free Radical / Inflammatory Immune Response / Lipopolysaccharide / Humans / Reactive Oxygen Species / Inflammatory disease / Mitochondrial dysfunction / Middle Aged / Lipopolysaccharides / Adult / Protein Expression / Periodontitis / Cardiovascular Diseases / Human Fibroblasts / Mitochondrial Membrane Potential / Citrate Synthase / Biochemistry and cell biology / PORPHYROMONAS GINGIVALIS / Inflammatory Immune Response / Lipopolysaccharide / Humans / Reactive Oxygen Species / Inflammatory disease / Mitochondrial dysfunction / Middle Aged / Lipopolysaccharides / Adult / Protein Expression / Periodontitis / Cardiovascular Diseases / Human Fibroblasts / Mitochondrial Membrane Potential / Citrate Synthase / Biochemistry and cell biology / PORPHYROMONAS GINGIVALIS
Role of Endoplasmic Reticulum Stress in Epithelial–Mesenchymal Transition of Alveolar Epithelial Cells
Apoptosis / Humans / Pulmonary fibrosis / Mutation / Mice / Animals / Male / Endoplasmic Reticulum / Rats / Epithelium / Human Fibroblasts / Protein Denaturation / Gene Expression Regulation / Animals / Male / Endoplasmic Reticulum / Rats / Epithelium / Human Fibroblasts / Protein Denaturation / Gene Expression Regulation
The Novel Deacetylase Inhibitor AR-42 Demonstrates Pre-Clinical Activity in B-Cell Malignancies In Vitro and In Vivo
Apoptosis / Multidisciplinary / Cell line / Humans / Chronic Lymphocytic Leukemia / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors
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