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cyclic GMP
cyclic GMP
Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway
Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol
In Central Obesity, Weight Loss Restores Platelet Sensitivity to Nitric Oxide and Prostacyclin
Obesity / Multidisciplinary / Insulin Resistance / Adipose tissue / Humans / Platelet aggregation / Weight Loss / cyclic AMP / Nitric oxide / Female / Male / Vascular endothelium / Endothelial dysfunction / Platelet activation mechanism / Platelet function / Adult / Central Obesity / Cyclic nucleotides / Body Weight / cyclic GMP / Adenosine Diphosphate / Sodium Nitroprusside / Platelet aggregation / Weight Loss / cyclic AMP / Nitric oxide / Female / Male / Vascular endothelium / Endothelial dysfunction / Platelet activation mechanism / Platelet function / Adult / Central Obesity / Cyclic nucleotides / Body Weight / cyclic GMP / Adenosine Diphosphate / Sodium Nitroprusside
Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: A new target to treat portal hypertension?
Cytokines / Hepatology / Humans / Portal hypertension / Liver / Blood Pressure / Animals / Male / Clinical Sciences / Rats / Carbon Tetrachloride / Protease Inhibitors / Endothelin-1 / Wistar Rats / Growth Factor / cyclic GMP / Portal vein / Vascular Resistance / Atrial Natriuretic Factor / Blood Pressure / Animals / Male / Clinical Sciences / Rats / Carbon Tetrachloride / Protease Inhibitors / Endothelin-1 / Wistar Rats / Growth Factor / cyclic GMP / Portal vein / Vascular Resistance / Atrial Natriuretic Factor
Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: A new target to treat portal hypertension?
Cytokines / Hepatology / Humans / Portal hypertension / Liver / Blood Pressure / Animals / Male / Clinical Sciences / Rats / Carbon Tetrachloride / Protease Inhibitors / Endothelin-1 / Wistar Rats / Growth Factor / cyclic GMP / Portal vein / Vascular Resistance / Atrial Natriuretic Factor / Blood Pressure / Animals / Male / Clinical Sciences / Rats / Carbon Tetrachloride / Protease Inhibitors / Endothelin-1 / Wistar Rats / Growth Factor / cyclic GMP / Portal vein / Vascular Resistance / Atrial Natriuretic Factor
Preparation and Pharmacological Characterization of trans -2-Amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1 H -indenes as D 2 -like Dopamine Receptor Agonists
Organic Chemistry / Medicinal Chemistry / cyclic AMP / Animals / dopamine receptor D4 / Rats / Swine / Radioligand Assay / Medicinal / Structure activity Relationship / cyclic GMP / Rats / Swine / Radioligand Assay / Medicinal / Structure activity Relationship / cyclic GMP
Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
Mitochondria / Ion Channels / Humans / Male / Nitrates / Exercise / Dietary Supplements / Adult / Oxidative phosphorylation / Oxygen Consumption / cyclic GMP / Nitrites / Biochemistry and cell biology / Mitochondrial Proteins / Exercise / Dietary Supplements / Adult / Oxidative phosphorylation / Oxygen Consumption / cyclic GMP / Nitrites / Biochemistry and cell biology / Mitochondrial Proteins
Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
Mitochondria / Ion Channels / Humans / Male / Nitrates / Exercise / Dietary Supplements / Adult / Oxidative phosphorylation / Oxygen Consumption / cyclic GMP / Nitrites / Biochemistry and cell biology / Mitochondrial Proteins / Exercise / Dietary Supplements / Adult / Oxidative phosphorylation / Oxygen Consumption / cyclic GMP / Nitrites / Biochemistry and cell biology / Mitochondrial Proteins
Androgens Regulate Phosphodiesterase Type 5 Expression and Functional Activity in Corpora Cavernosa
Endocrinology / Immunohistochemistry / Gene expression / Real-time RT-PCR / Western blotting / Biological Sciences / Humans / Testosterone / Female / Animals / Male / Androgens / Prostate / Penis / tESTIS / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Late onset hypogonadism / Western blot / Protein Expression / Rabbits / Epididymis / Female To Male / Level / cyclic GMP / Biological Sciences / Humans / Testosterone / Female / Animals / Male / Androgens / Prostate / Penis / tESTIS / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Late onset hypogonadism / Western blot / Protein Expression / Rabbits / Epididymis / Female To Male / Level / cyclic GMP
Reduced Plasma Cyclic GMP But Normal Renal Responses to Atrial Natriuretic Factor in Pre-Hypertension
Humans / Kidney / Hypertension / Blood Pressure / Male / Heart rate / Clinical Sciences / Factor / cyclic GMP / Atrial Natriuretic Factor / Glomerular Filtration Rate / Heart rate / Clinical Sciences / Factor / cyclic GMP / Atrial Natriuretic Factor / Glomerular Filtration Rate
Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade
Cystic Fibrosis / Signal Transduction / Humans / Nitric oxide / Pseudomonas aeruginosa / Phosphodiesterase Inhibitors / Sodium channel / Pseudomonas Aeruginosa / Hydrogen-Ion Concentration / Endosomes / Guanylate Cyclase / cyclic GMP / Biochemistry and cell biology / Phosphodiesterase Inhibitors / Sodium channel / Pseudomonas Aeruginosa / Hydrogen-Ion Concentration / Endosomes / Guanylate Cyclase / cyclic GMP / Biochemistry and cell biology
Preparation and Pharmacological Characterization of trans -2-Amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1 H -indenes as D 2 -like Dopamine Receptor Agonists
Organic Chemistry / Medicinal Chemistry / cyclic AMP / Animals / dopamine receptor D4 / Rats / Swine / Radioligand Assay / Medicinal / Structure activity Relationship / cyclic GMP / Rats / Swine / Radioligand Assay / Medicinal / Structure activity Relationship / cyclic GMP
Atrial Natriuretic Peptide Induces Mitogen-Activated Protein Kinase Phosphatase-1 in Human Endothelial Cells via Rac1 and NAD(P)H Oxidase/Nox2-Activation
Membrane Proteins / Signal Transduction / Humans / Capillaries / Endothelial Cells / Reactive Oxygen Species / Animals / Vascular endothelium / Glycoproteins / Lung / Mitogen Activated Protein Kinase / NADPH oxidase / Clinical Sciences / Rats / Endothelial cell / Circulation / Transfection / Cell Cycle Proteins / Protein Tyrosine Phosphatases / Guanylate Cyclase / cyclic GMP / Atrial Natriuretic Factor / Enzyme Induction / Cycloheximide / Reactive Oxygen Species / Animals / Vascular endothelium / Glycoproteins / Lung / Mitogen Activated Protein Kinase / NADPH oxidase / Clinical Sciences / Rats / Endothelial cell / Circulation / Transfection / Cell Cycle Proteins / Protein Tyrosine Phosphatases / Guanylate Cyclase / cyclic GMP / Atrial Natriuretic Factor / Enzyme Induction / Cycloheximide
Brucella melitensis Cyclic di-GMP Phosphodiesterase BpdA Controls Expression of Flagellar Genes
Bacteriology / Biological Sciences / Virulence / Humans / Mice / Animals / Flagella / Brucella melitensis / Brucellosis / cyclic GMP / Animals / Flagella / Brucella melitensis / Brucellosis / cyclic GMP
Nitric oxide depresses GABAA receptor function via coactivation of cGMP-dependent kinase and phosphodiesterase
Enzyme Inhibitors / Nitric oxide / Animals / Retina / Phosphodiesterase Inhibitors / Rats / Penicillamine / Protein Kinase / Guanylate Cyclase / cyclic GMP / Rats / Penicillamine / Protein Kinase / Guanylate Cyclase / cyclic GMP
The phosphodiesterase-5 inhibitor vardenafil improves cardiovascular dysfunction in experimental diabetes mellitus
British / Diabetes mellitus / Hemodynamics / Animals / Heart / Vascular endothelium / Left Ventricular Dysfunction / Phosphodiesterase Inhibitors / Rats / Myocardium / Transforming Growth Factor Beta / Imidazoles / Triazines / Vasodilation / cyclic GMP / Isometric Contraction / Vascular endothelium / Left Ventricular Dysfunction / Phosphodiesterase Inhibitors / Rats / Myocardium / Transforming Growth Factor Beta / Imidazoles / Triazines / Vasodilation / cyclic GMP / Isometric Contraction
Characterization of neutral endopeptidase in vascular cells, modulation of vasoactive peptide levels
RNA / Cell separation / Signal Transduction / Smooth muscle / Animals / Male / Polymerase Chain Reaction / Peptides / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / European / Rats / Endothelial cell / Wistar Rats / Primary Culture / Arachidonic Acid / cyclic GMP / Atrial Natriuretic Factor / Bradykinin / Male / Polymerase Chain Reaction / Peptides / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / European / Rats / Endothelial cell / Wistar Rats / Primary Culture / Arachidonic Acid / cyclic GMP / Atrial Natriuretic Factor / Bradykinin
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