Vascular Endothelial Growth Factor - Page 7

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor

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Hyperuricemia induces endothelial dysfunction

Nephrology / Urology / Dialysis / Humans / Kidney / Nitric oxide / Animals / Male / Drinking Water / Vascular endothelium / Endothelial dysfunction / Serum Uric Acid / Hyperuricemia / Clinical Sciences / Cattle / Uric Acid / Peripheral Vascular Disease / Rats / Nitric Oxide Synthase / Endothelial cell / Group / Renal disease / Xanthine Oxidase / Vascular Endothelial Growth Factor / Systolic blood pressure / Bovine Aortic Endothelial Cells / Nitric oxide / Animals / Male / Drinking Water / Vascular endothelium / Endothelial dysfunction / Serum Uric Acid / Hyperuricemia / Clinical Sciences / Cattle / Uric Acid / Peripheral Vascular Disease / Rats / Nitric Oxide Synthase / Endothelial cell / Group / Renal disease / Xanthine Oxidase / Vascular Endothelial Growth Factor / Systolic blood pressure / Bovine Aortic Endothelial Cells

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Increased expression of alpha-1-antitrypsin, glutathione S-transferase π and vascular endothelial growth factor in human pancreatic adenocarcinoma

Immunohistochemistry / Gene expression / Humans / Female / Male / Glutathione / Clinical Sciences / Aged / Middle Aged / Isoenzymes / Glutathione Transferase / Alpha-1 Antitrypsin / Adenocarcinoma / Vascular Endothelial Growth Factor / The American / Glutathione / Clinical Sciences / Aged / Middle Aged / Isoenzymes / Glutathione Transferase / Alpha-1 Antitrypsin / Adenocarcinoma / Vascular Endothelial Growth Factor / The American

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Vascular endothelial growth factor level changes during human embryo development in culture medium

Humans / Female / Embryonic Development / Culture Media / Vascular Endothelial Growth Factor / Embryo Development

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Reduced Vascular Endothelial Growth Factor Expression and Intra-Epidermal Nerve Fiber Loss in Human Diabetic Neuropathy

Endocrinology / Nutrition / Gene expression / Biopsy / Humans / Skin / Epidermis / Middle Aged / Foot / Diabetes Care / Laser Doppler Flowmetry / Vascular Endothelial Growth Factor / Skin / Epidermis / Middle Aged / Foot / Diabetes Care / Laser Doppler Flowmetry / Vascular Endothelial Growth Factor

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Seminal plasma induces mRNA expression of IL1 , IL6 and LIF in endometrial epithelial cells in vitro

Physiology / Clinical Sciences / mRna expression levels / Stromal Cells / In Vitro Studies / Enzyme Linked Immunosorbent Assay / Seminal Plasma / Vascular Endothelial Growth Factor / Transforming Growth Factor / Enzyme Linked Immunosorbent Assay / Seminal Plasma / Vascular Endothelial Growth Factor / Transforming Growth Factor

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Vascular endothelial growth factor induces manganese- superoxide dismutase expression in endothelial cells by a Rac1-regulated NADPH oxidase-dependent mechanism

Physiology / Western blotting / Humans / Reactive Oxygen Species / Vascular endothelium / Catalase / Medical Physiology / Superoxide Dismutase / NADPH oxidase / Endothelial cell / FASEB J / Xanthine Oxidase / Biochemistry and cell biology / Vascular Endothelial Growth Factor / Coronary artery / Catalase / Medical Physiology / Superoxide Dismutase / NADPH oxidase / Endothelial cell / FASEB J / Xanthine Oxidase / Biochemistry and cell biology / Vascular Endothelial Growth Factor / Coronary artery

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Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: Support for an endothelium-dependent mechanism

Cardiovascular / Immunohistochemistry / Cornea / Animals / Vehicle dynamic control / Vascular endothelium / Behavioral Animal Models / Mouse Model / Rats / Endothelial cell / Blood Flow / DR-AR Model / Biological markers / Rat Model / Aorta / Cell Survival / Blood Vessel / Vascular Endothelial Growth Factor / Vascular endothelium / Behavioral Animal Models / Mouse Model / Rats / Endothelial cell / Blood Flow / DR-AR Model / Biological markers / Rat Model / Aorta / Cell Survival / Blood Vessel / Vascular Endothelial Growth Factor

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Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis

Cell Cycle / Gene expression / Multidisciplinary / Chemokines and chemokine receptors / Cercopithecus aethiops / Humans / Mice / Female / Animals / Cytomegalovirus / Phenotype / Spectrum / Viral Infection / Neoplasms / G protein / Drug Targeting / Tumor Progression / Nude mice / Vascular Endothelial Growth Factor / Cell Growth / Humans / Mice / Female / Animals / Cytomegalovirus / Phenotype / Spectrum / Viral Infection / Neoplasms / G protein / Drug Targeting / Tumor Progression / Nude mice / Vascular Endothelial Growth Factor / Cell Growth

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Interleukin-1 induces the expression of vascular endothelial growth factor in human pericardial mesothelial cells

Cardiac Surgery / Humans / mRna expression levels / Epithelial cells / Time Dependent / Endothelial cell / Pericardium / Vascular Endothelial Growth Factor / Interleukin / Endothelial cell / Pericardium / Vascular Endothelial Growth Factor / Interleukin

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Blockade of Vascular Endothelial Growth Factor Suppresses Experimental Restenosis After Intraluminal Injury by Inhibiting Recruitment of Monocyte Lineage Cells

Nephrology / Oncology / Urology / Immunology / Cancer / Treatment / Immunohistochemistry / Cornea / Immunology of the Gut / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cell Division / Signal Transduction / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Immunotherapy / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Albuminuria / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / Blood Vessel / Protein Kinase Inhibitors / Lymphatic System / Nude mice / Neutralizing antibodies / Gene Transfer / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines / Treatment / Immunohistochemistry / Cornea / Immunology of the Gut / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cell Division / Signal Transduction / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Immunotherapy / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Albuminuria / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / Blood Vessel / Protein Kinase Inhibitors / Lymphatic System / Nude mice / Neutralizing antibodies / Gene Transfer / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines

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Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

Pharmacology / Genetics / Cancer treatment / Endothelial Cells / Mice / Animals / Gene / European / Gen / Endothelial cell / Neoplasms / Glycosyltransferases / Cell Proliferation / Growth Factor / Organic Chemicals / Vascular Endothelial Growth Factor / Knock Out Mice / Animals / Gene / European / Gen / Endothelial cell / Neoplasms / Glycosyltransferases / Cell Proliferation / Growth Factor / Organic Chemicals / Vascular Endothelial Growth Factor / Knock Out Mice

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Malignant hypertension, polycythemia, and paragangliomas

Pediatrics / Magnetic Resonance Imaging / MRI / Adolescent / Erythropoietin / Humans / VEGF / Female / Ct / DSA / Map / Polycythemia / Nervous System / Growth Factor / HIF / Vascular Endothelial Growth Factor / Humans / VEGF / Female / Ct / DSA / Map / Polycythemia / Nervous System / Growth Factor / HIF / Vascular Endothelial Growth Factor

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Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma

Clinical Trial / British / Treatment Outcome / Bladder Cancer / Humans / Female / Male / High Performance Liquid Chromatography / Aged / Middle Aged / Side Effect / Mass Spectroscopy / Proteinuria / Antineoplastic Agents / Enzyme Linked Immunosorbent Assay / Vascular Endothelial Growth Factor / Phase II Trial / Female / Male / High Performance Liquid Chromatography / Aged / Middle Aged / Side Effect / Mass Spectroscopy / Proteinuria / Antineoplastic Agents / Enzyme Linked Immunosorbent Assay / Vascular Endothelial Growth Factor / Phase II Trial

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Gene transfer of CuZn superoxide dismutase enhances the synthesis of vascular endothelial growth factor

Western blotting / Protein synthesis / Signal Transduction / Molecular and cellular biology / Humans / Copper / Reactive Oxygen Species / Mice / Nitric oxide / Animals / Gene transfer techniques / Catalase / Zinc / Heme Oxygenase / Plasmids / Superoxide Dismutase / Hydrogen Peroxide / mRna expression levels / Endothelial cell / Transfection / Enzyme Linked Immunosorbent Assay / Molecular and Cellular Biochemistry / Superoxides / Response Elements / Biochemistry and cell biology / Gene Transfer / Vascular Endothelial Growth Factor / Copper / Reactive Oxygen Species / Mice / Nitric oxide / Animals / Gene transfer techniques / Catalase / Zinc / Heme Oxygenase / Plasmids / Superoxide Dismutase / Hydrogen Peroxide / mRna expression levels / Endothelial cell / Transfection / Enzyme Linked Immunosorbent Assay / Molecular and Cellular Biochemistry / Superoxides / Response Elements / Biochemistry and cell biology / Gene Transfer / Vascular Endothelial Growth Factor

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