Transgene Expression

Intracisternal rSV40 administration provides effective pan-CNS transgene expression

Genetics / Gene Therapy / Immunohistochemistry / Oxidative Stress / Apoptosis / HIV / Biological Sciences / Female / Animals / Gene transfer techniques / Glutathione Peroxidase / Central Nervous System / Neurons / Superoxide Dismutase / Gene Delivery / Rats / Transgene Expression / Mannitol / Gene Transfer / Neuroprotective Agents / HIV / Biological Sciences / Female / Animals / Gene transfer techniques / Glutathione Peroxidase / Central Nervous System / Neurons / Superoxide Dismutase / Gene Delivery / Rats / Transgene Expression / Mannitol / Gene Transfer / Neuroprotective Agents

Transgenic MMP-2 expression induces latent cardiac mitochondrial dysfunction

Mice / Animals / Biochemical / Creatine Kinase / Lipid peroxidation / Mitochondrial dysfunction / Myocardial Infarction / Myocardium / Necrosis / Infarct Size / Ischemia–reperfusion / Transgene Expression / Ischemic Preconditioning / Biochemistry and cell biology / Matrix Metalloproteinase / Mitochondrial dysfunction / Myocardial Infarction / Myocardium / Necrosis / Infarct Size / Ischemia–reperfusion / Transgene Expression / Ischemic Preconditioning / Biochemistry and cell biology / Matrix Metalloproteinase

Lentiviral Vector Gene Transfer into Fetal Rhesus Monkeys (Macaca mulatta): Lung-Targeting Approaches

Pharmacology / Genetics / Technology / Flow Cytometry / Fluorescence Microscopy / Immunohistochemistry / Ultrasound / HIV / Biological Sciences / Molecular / Hematopoietic Stem Cells / Humans / Animals / Blood sampling / Gene transfer techniques / Polymerase Chain Reaction / Lung / Rhesus Monkey / Model System / Macaca Mulatta / Transgene Expression / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Gene Transfer / Immunohistochemistry / Ultrasound / HIV / Biological Sciences / Molecular / Hematopoietic Stem Cells / Humans / Animals / Blood sampling / Gene transfer techniques / Polymerase Chain Reaction / Lung / Rhesus Monkey / Model System / Macaca Mulatta / Transgene Expression / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Gene Transfer

Inducible Nephrin Transgene Expression in Podocytes Rescues Nephrin-Deficient Mice from Perinatal Death

Animal Behavior / Membrane Proteins / Humans / Kidney / Mice / Animals / American / Phenotype / Fluorescent Antibody Technique / Genotype / Rats / Doxycycline / Body Weight / Perinatal mortality / Proteinuria / Transgene Expression / Podocytes / Gene Expression Regulation / Animals / American / Phenotype / Fluorescent Antibody Technique / Genotype / Rats / Doxycycline / Body Weight / Perinatal mortality / Proteinuria / Transgene Expression / Podocytes / Gene Expression Regulation

Prolonged Biologically Active Transgene Expression Driven by HSV Latency Active Promoter 2 (LAP2) in Brain In Vivo

Pharmacology / Technology / Gene Therapy / Gene expression / Biological Sciences / Molecular / Brain / Low Dose / Mice / Chronic Disease / Female / Animals / Therapy / Substantia nigra / Rats / Biological activity / Transgene Expression / Molecular Targeted Therapy / Parkinson Disease / Herpes Simplex Virus / Molecular / Brain / Low Dose / Mice / Chronic Disease / Female / Animals / Therapy / Substantia nigra / Rats / Biological activity / Transgene Expression / Molecular Targeted Therapy / Parkinson Disease / Herpes Simplex Virus

Correction of Laminin-5 Deficiency in Human Epidermal Stem Cells by Transcriptionally Targeted Lentiviral Vectors

Genetics / Technology / Stem Cells / Gene Therapy / Health / Stem Cell / Gene expression / Biological Sciences / Molecular / Cell Differentiation / Humans / Keratinocytes / Basement Membrane / Mice / Animals / Epidermolysis Bullosa / Lentivirus / Epidermis / Transgene Expression / Molecular Targeted Therapy / Gene Transfer / Cell Adhesion Molecules / Tissue Specificity / Skin Biopsy / Stem Cell / Gene expression / Biological Sciences / Molecular / Cell Differentiation / Humans / Keratinocytes / Basement Membrane / Mice / Animals / Epidermolysis Bullosa / Lentivirus / Epidermis / Transgene Expression / Molecular Targeted Therapy / Gene Transfer / Cell Adhesion Molecules / Tissue Specificity / Skin Biopsy

Gene transfer into canine myoblasts

Technology / Biological Sciences / Gene Delivery / Calcium Phosphate / Transgene Expression / Plasmid DNA / Cytotechnology / Gene Transfer / Plasmid DNA / Cytotechnology / Gene Transfer

A transgenic mouse model for mammary carcinogenesis

Breast Cancer / Gene expression / Disease susceptibility / Transgenic Mice / Mutation / Mice / Female / Animals / Oncogene / Carcinogens / Clinical Sciences / Mouse Model / Mammary gland / Model System / Flow analysis / Genomic instability / Amino Acid Profile / Cell Proliferation / Transgenic Mouse Technology / Transgene Expression / Mice / Female / Animals / Oncogene / Carcinogens / Clinical Sciences / Mouse Model / Mammary gland / Model System / Flow analysis / Genomic instability / Amino Acid Profile / Cell Proliferation / Transgenic Mouse Technology / Transgene Expression

Inducible Nephrin Transgene Expression in Podocytes Rescues Nephrin-Deficient Mice from Perinatal Death

Animal Behavior / Membrane Proteins / Humans / Kidney / Mice / Animals / American / Phenotype / Fluorescent Antibody Technique / Genotype / Rats / Doxycycline / Body Weight / Perinatal mortality / Proteinuria / Transgene Expression / Podocytes / Gene Expression Regulation / Animals / American / Phenotype / Fluorescent Antibody Technique / Genotype / Rats / Doxycycline / Body Weight / Perinatal mortality / Proteinuria / Transgene Expression / Podocytes / Gene Expression Regulation

Tumor Endothelium-specific Transgene Expression Directed by Vascular Endothelial Growth Factor Receptor2 (Flk-1) Promoter/Enhancer Sequences1,2

Cancer / Gene expression / Transgenic Mice / Epidermal Growth Factor/ErbB receptors / Mice / Female / Animals / Male / Vascular endothelium / Fibrosarcoma / Specific Activity / Transgene Expression / Blood Vessel / Adenocarcinoma / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Female / Animals / Male / Vascular endothelium / Fibrosarcoma / Specific Activity / Transgene Expression / Blood Vessel / Adenocarcinoma / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase

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