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Toxicity Tests

Targeting of Mitochondria-Endoplasmic Reticulum by Fluorescent Macrocyclic Compounds

Flow Cytometry / Breast Cancer / Fluorescence Microscopy / Mitochondria / Fluorescent Dyes and Reagents / Confocal Microscopy / Apoptosis / Multidisciplinary / Humans / Endoplasmic Reticulum / Fluorescence Imaging / PLoS one / Adult / Pyridines / Toxicity Tests / Mitochondrial Membrane Potential / Cell Survival / Ligands / Plasma Membrane / Breast Cancer Cells / Proof of Concept / Confocal Microscopy / Apoptosis / Multidisciplinary / Humans / Endoplasmic Reticulum / Fluorescence Imaging / PLoS one / Adult / Pyridines / Toxicity Tests / Mitochondrial Membrane Potential / Cell Survival / Ligands / Plasma Membrane / Breast Cancer Cells / Proof of Concept
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Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae

Aquatic Toxicology / Danio rerio / Biological Sciences / Developmental Coordination Disorder / Environmental Sciences / Stress response / Animals / Aryl Hydrocarbon Receptor / CHEMICAL SCIENCES / Larva / Zebrafish / Toxicity Tests / Gene Expression Analysis / Embryos / Cell Cycle Control / Chronic Toxicity / Differential Gene Expression / Toxicity Testing / Gene Expression Regulation / aniline Compounds / Gene expression profiling / Differential expression / Stress response / Animals / Aryl Hydrocarbon Receptor / CHEMICAL SCIENCES / Larva / Zebrafish / Toxicity Tests / Gene Expression Analysis / Embryos / Cell Cycle Control / Chronic Toxicity / Differential Gene Expression / Toxicity Testing / Gene Expression Regulation / aniline Compounds / Gene expression profiling / Differential expression
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Potential of a Khaya ivorensis – Alstonia boonei extract combination as antimalarial prophylactic remedy

Complementary and Alternative Medicine / Traditional Medicine / Plant Biology / Malaria / Ethnopharmacology / Medicinal Plants / Mice / Female / Animals / Male / Meliaceae / Lancet / Plant extracts / Antimalarials / Toxicity Tests / Lethal Dose / Plasmodium berghei / Medicinal Plants / Mice / Female / Animals / Male / Meliaceae / Lancet / Plant extracts / Antimalarials / Toxicity Tests / Lethal Dose / Plasmodium berghei
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New Antimalarial Hits from Dacryodes edulis (Burseraceae) - Part I: Isolation, In Vitro Activity, In Silico “drug-likeness� and Pharmacokinetic Profiles

Drug interactions / Multidisciplinary / Cell line / Animals / PLoS one / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine
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LONG-TERM CORROSION-INDUCED COPPER RUNOFF FROM NATURAL AND ARTIFICIAL PATINA AND ITS ENVIRONMENTAL IMPACT

Water / Environmental Monitoring / Risk assessment / Environmental Pollution / Corrosion / Biological Sciences / Environmental Sciences / Copper / Environmental Impact / CHEMICAL SCIENCES / Risk Assessment / Toxicity Tests / Environmental Toxicology and Chemistry / Water Movements / Environmental / Environment / Soil Pollutants / Biological Sciences / Environmental Sciences / Copper / Environmental Impact / CHEMICAL SCIENCES / Risk Assessment / Toxicity Tests / Environmental Toxicology and Chemistry / Water Movements / Environmental / Environment / Soil Pollutants
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Biopesticides from plants: Calceolaria integrifolia s.l

Drosophila melanogaster / Flavonoids / Biological Sciences / Insecticides / Environmental Sciences / Animals / Naphthoquinones / Cholinesterase inhibitors / Gallic acid / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Toxicity Tests / Environmental / Scrophulariaceae / Animals / Naphthoquinones / Cholinesterase inhibitors / Gallic acid / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Toxicity Tests / Environmental / Scrophulariaceae
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Preliminary interlaboratory comparison of the ex vivo dual human placental perfusion system

Reproduction / Pregnancy / Humans / Placenta / Reproductive toxicology / Female / Perfusion / Laboratories / Public health systems and services research / Reproducibility of Results / Reproductive / Toxicity Tests / Curve fitting / Environmental Pollutants / Area Under the Curve / Maternal-fetal exchange / Female / Perfusion / Laboratories / Public health systems and services research / Reproducibility of Results / Reproductive / Toxicity Tests / Curve fitting / Environmental Pollutants / Area Under the Curve / Maternal-fetal exchange
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Antiplasmodial activity of Aspidosperma indole alkaloids

Complementary and Alternative Medicine / Plant Biology / Phytomedicine / Cell line / Humans / Animals / Drug Resistance / Alkaloids / Plant extracts / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinolines / Chloroquine / Structure activity Relationship / Indole Alkaloids / Molecular Structure / Animals / Drug Resistance / Alkaloids / Plant extracts / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinolines / Chloroquine / Structure activity Relationship / Indole Alkaloids / Molecular Structure
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Preliminary ecotoxicological characterization of a new energetic substance, CL-20

Polymorphism / Ecotoxicology / Seed germination / Multidisciplinary / Toxicity / Nitrification / Oxidoreductases / Bacteria / Statistical Significance / Bioluminescence / Nitrogen / Luminescence / Marine Bacteria / Soil Microbiology / Environmental Impact / Vibrio / Analysis of Variance / Gramineae / Water soluble polymers / Toxicity Tests / Triazines / Acute Toxicity / Chlorophyta / Heterocyclic compounds / Toxicity Test / Soil Pollutants / Microbial community / Thallophyta / Nitrification / Oxidoreductases / Bacteria / Statistical Significance / Bioluminescence / Nitrogen / Luminescence / Marine Bacteria / Soil Microbiology / Environmental Impact / Vibrio / Analysis of Variance / Gramineae / Water soluble polymers / Toxicity Tests / Triazines / Acute Toxicity / Chlorophyta / Heterocyclic compounds / Toxicity Test / Soil Pollutants / Microbial community / Thallophyta
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Larvicidal, antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region, Tanzania

Complementary and Alternative Medicine / Traditional Medicine / Artemia / Medicinal Plants / Tanzania / Diabetes mellitus / Escherichia coli / Vibrio cholerae / Cryptococcus Neoformans / Animals / Antimicrobial activity / Methanol / Staphylococcus aureus / Candida albicans / Fruit / Plant Roots / Antifungal Activity / Pseudomonas aeruginosa / Larvicidal and antimicrobial activities of plants / Antibacterial activity / Anti-Bacterial Agents / MDR Salmonella typhi / Plant extracts / Culex quinquefasciatus / Larva / Antifungal Agents / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Toxicity Tests / Bacillus Anthracis / Bioactive Compound / Plant Leaves / Diabetes mellitus / Escherichia coli / Vibrio cholerae / Cryptococcus Neoformans / Animals / Antimicrobial activity / Methanol / Staphylococcus aureus / Candida albicans / Fruit / Plant Roots / Antifungal Activity / Pseudomonas aeruginosa / Larvicidal and antimicrobial activities of plants / Antibacterial activity / Anti-Bacterial Agents / MDR Salmonella typhi / Plant extracts / Culex quinquefasciatus / Larva / Antifungal Agents / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Toxicity Tests / Bacillus Anthracis / Bioactive Compound / Plant Leaves
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New Antimalarial Hits from Dacryodes edulis (Burseraceae) - Part I: Isolation, In Vitro Activity, In Silico “drug-likeness� and Pharmacokinetic Profiles

Drug interactions / Multidisciplinary / Cell line / Animals / PLoS one / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine
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Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae

Aquatic Toxicology / Danio rerio / Biological Sciences / Developmental Coordination Disorder / Environmental Sciences / Stress response / Animals / Aryl Hydrocarbon Receptor / CHEMICAL SCIENCES / Larva / Zebrafish / Toxicity Tests / Gene Expression Analysis / Embryos / Cell Cycle Control / Chronic Toxicity / Differential Gene Expression / Toxicity Testing / Gene Expression Regulation / aniline Compounds / Gene expression profiling / Differential expression / Stress response / Animals / Aryl Hydrocarbon Receptor / CHEMICAL SCIENCES / Larva / Zebrafish / Toxicity Tests / Gene Expression Analysis / Embryos / Cell Cycle Control / Chronic Toxicity / Differential Gene Expression / Toxicity Testing / Gene Expression Regulation / aniline Compounds / Gene expression profiling / Differential expression
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Preliminary interlaboratory comparison of the ex vivo dual human placental perfusion system

Reproduction / Comparative Study / In Vitro / Pregnancy / Humans / Placenta / Reproductive toxicology / Female / Perfusion / Laboratories / Public health systems and services research / Reproducibility of Results / Reproductive / Toxicity Tests / Curve fitting / Environmental Pollutants / Area Under the Curve / Maternal-fetal exchange / Placenta / Reproductive toxicology / Female / Perfusion / Laboratories / Public health systems and services research / Reproducibility of Results / Reproductive / Toxicity Tests / Curve fitting / Environmental Pollutants / Area Under the Curve / Maternal-fetal exchange
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Biopesticides from plants: Calceolaria integrifolia s.l

Drosophila melanogaster / Flavonoids / Biological Sciences / Insecticides / Environmental Sciences / Animals / Naphthoquinones / Cholinesterase inhibitors / Gallic acid / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Toxicity Tests / Environmental / Scrophulariaceae / Animals / Naphthoquinones / Cholinesterase inhibitors / Gallic acid / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Toxicity Tests / Environmental / Scrophulariaceae
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A panel of biological tests reveals developmental effects of pharmaceutical pollutants on late stage zebrafish embryos

Animal Behavior / Caffeine / Reproductive toxicology / Animals / Heart rate / Theophylline / Valproic Acid / Carbamazepine / Public health systems and services research / Zebrafish / Psychotropic Drugs / Toxicity Tests / Pentobarbital / Motor activity / Lithium chloride / Theophylline / Valproic Acid / Carbamazepine / Public health systems and services research / Zebrafish / Psychotropic Drugs / Toxicity Tests / Pentobarbital / Motor activity / Lithium chloride
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New Furan Side Tetracyclic Allopsoralen Derivatives:  Synthesis and Photobiological Evaluation

Organic Chemistry / Medicinal Chemistry / Humans / Darkness / Animals / Polymerase Chain Reaction / Skin / Medicinal / Toxicity Tests / Structure activity Relationship / Antineoplastic Agents / Furans / "Intercalating Agents" / Polymerase Chain Reaction / Skin / Medicinal / Toxicity Tests / Structure activity Relationship / Antineoplastic Agents / Furans / "Intercalating Agents"
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