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Rats
Rats
Hyperoxic Treatment Induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model
Immunohistochemistry / Gene expression / Multidisciplinary / Tumor Hypoxia / Female / Animals / Cell Death / PLoS one / Rats / Epithelial cells / Hyperbaric Oxygen / Hyperoxia / Tumor Growth / Blood Vessel / Epithelial to Mesenchymal Transition / Control Group / Adenocarcinoma / Treatment Effect / Animals / Cell Death / PLoS one / Rats / Epithelial cells / Hyperbaric Oxygen / Hyperoxia / Tumor Growth / Blood Vessel / Epithelial to Mesenchymal Transition / Control Group / Adenocarcinoma / Treatment Effect
Cold environmental stress induces detrusor overactivity via resiniferatoxin-sensitive nerves in conscious rats
Animal Behavior / Consciousness / Stress / Immunohistochemistry / Female / Animals / Urodynamics / Neurons / Clinical Sciences / Rats / Time Factors / Diterpenes / Rat / Environmental Stress / Cold / Neurosciences / Neurourology / Urinary Bladder / Calcitonin Gene-Related Peptide / Animals / Urodynamics / Neurons / Clinical Sciences / Rats / Time Factors / Diterpenes / Rat / Environmental Stress / Cold / Neurosciences / Neurourology / Urinary Bladder / Calcitonin Gene-Related Peptide
Vascular endothelial growth factor accelerates renal recovery in experimental thrombotic microangiopathy1
Microcirculation / Kidney / Ischemia / Animals / Vehicle dynamic control / Male / Vascular endothelium / Hemolytic Uremic Syndrome / Renal Function / Clinical Sciences / Rats / Endothelial cell / Thrombosis / Thrombotic Microangiopathy / Growth Factor / immunoglobulin G / Vascular Endothelial Growth Factor / Experimental Model / Male / Vascular endothelium / Hemolytic Uremic Syndrome / Renal Function / Clinical Sciences / Rats / Endothelial cell / Thrombosis / Thrombotic Microangiopathy / Growth Factor / immunoglobulin G / Vascular Endothelial Growth Factor / Experimental Model
Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis
Extracellular Matrix / Cell Division / Heparin / Kidney / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Growth Factor / Extracellular Matrix Proteins / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Growth Factor / Extracellular Matrix Proteins
Hyperuricemia induces endothelial dysfunction
Physiology / Calcium / Mitochondria / Humans / Kidney / Reactive Oxygen Species / Nitric oxide / Animals / Male / Drinking Water / Vascular endothelium / Medical Physiology / Endothelial dysfunction / Serum Uric Acid / Hyperuricemia / Clinical Sciences / Cattle / Hydrogen Peroxide / Uric Acid / Peripheral Vascular Disease / Rats / Oxygen / Nitric Oxide Synthase / Endothelial cell / Group / ENDOTHELIUM / Cytoplasm / Renal disease / Xanthine Oxidase / Biochemistry and cell biology / Vascular Endothelial Growth Factor / Systolic blood pressure / Bovine Aortic Endothelial Cells / Reactive Oxygen Species / Nitric oxide / Animals / Male / Drinking Water / Vascular endothelium / Medical Physiology / Endothelial dysfunction / Serum Uric Acid / Hyperuricemia / Clinical Sciences / Cattle / Hydrogen Peroxide / Uric Acid / Peripheral Vascular Disease / Rats / Oxygen / Nitric Oxide Synthase / Endothelial cell / Group / ENDOTHELIUM / Cytoplasm / Renal disease / Xanthine Oxidase / Biochemistry and cell biology / Vascular Endothelial Growth Factor / Systolic blood pressure / Bovine Aortic Endothelial Cells
Carnosine analogues containing NO-donor substructures: Synthesis, physico-chemical characterization and preliminary pharmacological profile
Organic Chemistry / Antioxidants / Humans / Copper / Nitric oxide / Animals / Male / Rats / Reperfusion injury / Vasodilation / Drug Stability / Aldehydes / Carnosine / Animals / Male / Rats / Reperfusion injury / Vasodilation / Drug Stability / Aldehydes / Carnosine
Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification
Organic Chemistry / Humans / Animals / Drug Design / Acetylcholine / Microdialysis / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Area Under Curve / Benzamides / Microdialysis / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Area Under Curve / Benzamides
Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study
Cardiovascular disease / Gene expression / Humans / Animals / Male / Glutathione / Heart / ATP synthase / Metallothionein / Beta-Catenin / Creatine Kinase / Rats / Wistar Rats / Global Gene Expression / Biochemistry and cell biology / Gene Expression Regulation / Gene expression profiling / Quantitative polymerase chain reaction / Glutathione / Heart / ATP synthase / Metallothionein / Beta-Catenin / Creatine Kinase / Rats / Wistar Rats / Global Gene Expression / Biochemistry and cell biology / Gene Expression Regulation / Gene expression profiling / Quantitative polymerase chain reaction
Probucol restores the defective leukocyte–endothelial interaction in experimental diabetes
Immunohistochemistry / Oxidative Stress / Fluorescent Dyes and Reagents / Free Radical / Antioxidants / Blood Glucose / Diabetes mellitus / Hemodynamics / Animals / Male / Vascular endothelium / European / Rats / Endothelial cell / Cross Section / Wistar Rats / Type 2 Diabetes Mellitus / Diabetic Rat / Weight Gain / Leukocytes / Superoxides / Intravital Microscopy / Blood Glucose / Diabetes mellitus / Hemodynamics / Animals / Male / Vascular endothelium / European / Rats / Endothelial cell / Cross Section / Wistar Rats / Type 2 Diabetes Mellitus / Diabetic Rat / Weight Gain / Leukocytes / Superoxides / Intravital Microscopy
ETA Receptor Blockade Decreases Vascular Superoxide Generation in DOCA-Salt Hypertension
Oxidative Stress / Hypertension / Blood Pressure / Animals / Plant tissue Culture Techniques / Male / Acetylcholine / Proteins / Clinical Sciences / Neutrophils / Rats / Western blot / Wistar Rats / Aorta / Vasodilation / Superoxide Anion / Sodium Chloride / Superoxides / Tyrosine / Systolic blood pressure / Ethidium bromide / Male / Acetylcholine / Proteins / Clinical Sciences / Neutrophils / Rats / Western blot / Wistar Rats / Aorta / Vasodilation / Superoxide Anion / Sodium Chloride / Superoxides / Tyrosine / Systolic blood pressure / Ethidium bromide
Quercetin promotes glioma growth in a rat model
Cell Division / Glioma / Animals / Male / Rats / Quercetin / Wistar Rats / Food Sciences / Food and Chemical Toxicology / Brain Neoplasms / Quercetin / Wistar Rats / Food Sciences / Food and Chemical Toxicology / Brain Neoplasms
Pharmacological characterization of SB-710411 (Cpa-c[D-Cys-Pal-D-Trp-Lys-Val-Cys]-Cpa-amide), a novel peptidic urotensin-II receptor antagonist
British / Humans / G protein-coupled receptors / Animals / Male / Cyclic peptides / Vasoconstriction / Rats / Endothelin-1 / Cyclic peptides / Vasoconstriction / Rats / Endothelin-1
Sequential damage in mitochondrial complexes by peroxidative stress
Mitochondria / Biological Sciences / Electron Transfer / Animals / Male / Cytochrome C / Glutathione / Mitochondrial Respiratory Chain / Electron Transport / Cytochrome oxidase / Enzyme / Cytochrome B / Rats / Specific Activity / Side Effect / Pantothenic Acid / Succinate Dehydrogenase / Oxidation-Reduction / Citrate Synthase / Drug treatment / Gamma-Aminobutyric Acid / Neurochemical / Cytochrome C / Glutathione / Mitochondrial Respiratory Chain / Electron Transport / Cytochrome oxidase / Enzyme / Cytochrome B / Rats / Specific Activity / Side Effect / Pantothenic Acid / Succinate Dehydrogenase / Oxidation-Reduction / Citrate Synthase / Drug treatment / Gamma-Aminobutyric Acid / Neurochemical
Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
Microbiology / Immunology / Multiple sclerosis / Medical Microbiology / British / Immunohistochemistry / Immunology of the Gut / Neuroimmunology / Western blotting / Neuroprotection / Humans / Mice / Female / Animals / Spinal Cord / Neuroinflammation / Therapy / Male / Drug Design / Astrocyte / Parasite Immunology / Central Nervous System / Astrocytes / Clinical Sciences / Disease mapping / Fluorescent Antibody Technique / Rats / Animal models / Aquaporin / Glial Fibrillary Acidic Protein / Body Weight / Veterinary Sciences / Experimental Autoimmune Encephalomyelitis / Neurosciences / Strongyloidiasis / Whole Body / immunoglobulin G / Gliosis / Severity of Illness Index / Immunohistochemistry / Immunology of the Gut / Neuroimmunology / Western blotting / Neuroprotection / Humans / Mice / Female / Animals / Spinal Cord / Neuroinflammation / Therapy / Male / Drug Design / Astrocyte / Parasite Immunology / Central Nervous System / Astrocytes / Clinical Sciences / Disease mapping / Fluorescent Antibody Technique / Rats / Animal models / Aquaporin / Glial Fibrillary Acidic Protein / Body Weight / Veterinary Sciences / Experimental Autoimmune Encephalomyelitis / Neurosciences / Strongyloidiasis / Whole Body / immunoglobulin G / Gliosis / Severity of Illness Index
Functional Characterization and Expression of a Cytosolic Iron-Superoxide Dismutase from Cowpea Root Nodules
Physiology / Electrophysiology / British / Immunohistochemistry / Mitochondria / Gene expression / Western blotting / Free Radical / Biological Sciences / Phylogeny / Plant Physiology / Sequence alignment / Escherichia coli / Nitric oxide / Animals / Plant / Male / Vascular endothelium / American / Cyclic peptides / Iron / Medical Physiology / Soybean / Plant Roots / Superoxide Dismutase / Enzyme / Subcellular Localization / Molecular cloning / Rats / Fabaceae / Phaseolus vulgaris / Radioligand Assay / Endothelin-1 / Potassium Channels / Wistar Rats / Common bean / Amino Acid Profile / Amino Acid Sequence / Glycine max / Carotid Artery / Recombinant Proteins / Vasodilation / Ligands / Catalytic Activity / Vigna Unguiculata / PISUM SATIVUM / Piperidines / Chlorides / Endothelins / Molecular Sequence Data / Gene expression / Western blotting / Free Radical / Biological Sciences / Phylogeny / Plant Physiology / Sequence alignment / Escherichia coli / Nitric oxide / Animals / Plant / Male / Vascular endothelium / American / Cyclic peptides / Iron / Medical Physiology / Soybean / Plant Roots / Superoxide Dismutase / Enzyme / Subcellular Localization / Molecular cloning / Rats / Fabaceae / Phaseolus vulgaris / Radioligand Assay / Endothelin-1 / Potassium Channels / Wistar Rats / Common bean / Amino Acid Profile / Amino Acid Sequence / Glycine max / Carotid Artery / Recombinant Proteins / Vasodilation / Ligands / Catalytic Activity / Vigna Unguiculata / PISUM SATIVUM / Piperidines / Chlorides / Endothelins / Molecular Sequence Data
Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures
Neurobiology Of Disease / Free Radicals / Oxidative Stress / Mitochondria / Neurobiology / Energy Metabolism / Free Radical / Glutamate / Mitochondrial DNA / Animals / Cell Death / Retina / Glial Cell / Neurons / Lipid peroxidation / Clinical Sciences / Rats / Oxidative Damage / Degeneration / Retinal Ganglion Cells / Wistar Rats / Neurosciences / Glutamic Acid / Glutamate Transporter / Energy Metabolism / Free Radical / Glutamate / Mitochondrial DNA / Animals / Cell Death / Retina / Glial Cell / Neurons / Lipid peroxidation / Clinical Sciences / Rats / Oxidative Damage / Degeneration / Retinal Ganglion Cells / Wistar Rats / Neurosciences / Glutamic Acid / Glutamate Transporter
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