RNA interference

Loss of Protein Kinase PKR Expression in Human HeLa Cells Complements the Vaccinia Virus E3L Deletion Mutant Phenotype by Restoration of Viral Protein Synthesis

Virology / Apoptosis / Gene Silencing / Protein synthesis / Biological Sciences / RNA interference / Humans / Mutation / Virus / Phosphorylation / Phenotype / RNA-binding proteins / HeLa cells / Vaccinia Virus / Complement / Protein Kinase / double-stranded RNA / RNA interference / Humans / Mutation / Virus / Phosphorylation / Phenotype / RNA-binding proteins / HeLa cells / Vaccinia Virus / Complement / Protein Kinase / double-stranded RNA

Class-, gene-, and group-specific HLA silencing by lentiviral shRNA delivery

Molecular Medicine / Gene Therapy / Regenerative Medicine / Gene Silencing / RNA interference / Cell line / Humans / Natural Killer cells / Lentivirus / T lymphocytes / B Lymphocytes / Immune Tolerance / Cell free System / NK Cell / In Vitro Transcription / Interferon gamma / Cell line / Humans / Natural Killer cells / Lentivirus / T lymphocytes / B Lymphocytes / Immune Tolerance / Cell free System / NK Cell / In Vitro Transcription / Interferon gamma

MicroRNA-196a Is a Potential Marker of Progression during Barrett\'s Metaplasia-Dysplasia-Invasive Adenocarcinoma Sequence in Esophagus

Micro Rna / MicroRNA / Cancer / Gene Silencing / RNA interference / Humans / Female / Male / American / Keratin / Sequence / Aged / Middle Aged / microRNAs / Neoplasm Invasiveness / Adult / Esophagus / Retrospective Studies / Disease Progression / Adenocarcinoma / Humans / Female / Male / American / Keratin / Sequence / Aged / Middle Aged / microRNAs / Neoplasm Invasiveness / Adult / Esophagus / Retrospective Studies / Disease Progression / Adenocarcinoma

MicroRNA-196a Is a Potential Marker of Progression during Barrett\'s Metaplasia-Dysplasia-lnvasive Adenocarcinoma Sequence in Esophagus

Micro Rna / MicroRNA / Cancer / Gene Silencing / RNA interference / Humans / Female / Male / American / Keratin / Sequence / Aged / Middle Aged / microRNAs / Neoplasm Invasiveness / Adult / Esophagus / Retrospective Studies / Disease Progression / Adenocarcinoma / Humans / Female / Male / American / Keratin / Sequence / Aged / Middle Aged / microRNAs / Neoplasm Invasiveness / Adult / Esophagus / Retrospective Studies / Disease Progression / Adenocarcinoma

Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

Myristoyl CoA: protein N-myristoyltransferase: an essential enzyme and potential drug target in kinetoplastid parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

Phosphatidic Acid Induces Ligand-independent Epidermal Growth Factor Receptor Endocytic Traffic through PDE4 Activation

Molecular Biology / Flow Cytometry / Signal Transduction / Biological Sciences / RNA interference / Humans / Mice / Endocytosis / cyclic AMP / Animals / Epidermal Growth Factor Receptor / HeLa cells / Phospholipase D / Propranolol / Hydrolysis / Endosomes / Phosphatidic acid / Clathrin / Immunoblotting / Humans / Mice / Endocytosis / cyclic AMP / Animals / Epidermal Growth Factor Receptor / HeLa cells / Phospholipase D / Propranolol / Hydrolysis / Endosomes / Phosphatidic acid / Clathrin / Immunoblotting

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Skeletal muscle biology / Diabetes / Membrane Proteins / RNA interference / Insulin Resistance / Cell line / Mice / Electroporation / Female / Animals / Gene transfer techniques / Male / Lipid metabolism / Rats / Oxidative phosphorylation / Wistar Rats / Recombinant Proteins / Gene expression profiling / Cell line / Mice / Electroporation / Female / Animals / Gene transfer techniques / Male / Lipid metabolism / Rats / Oxidative phosphorylation / Wistar Rats / Recombinant Proteins / Gene expression profiling

Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways

Signal Transduction / RNA interference / Pregnancy / Cerebral Cortex / Curcumin / Female / Animals / Astrocyte / Neurons / Astrocytes / Antioxidant Activity / Rats / Neurodegenerative Disease / Transfection / Cell Survival / Enzyme Linked Immunosorbent Assay / Female / Animals / Astrocyte / Neurons / Astrocytes / Antioxidant Activity / Rats / Neurodegenerative Disease / Transfection / Cell Survival / Enzyme Linked Immunosorbent Assay

Mammalian RNAi: a practical guide

Technology / Gene Silencing / Genetic Engineering / Biological Sciences / RNA interference / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling

Mammalian RNAi: a practical guide

Technology / Gene Silencing / Genetic Engineering / Biological Sciences / RNA interference / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling

Chaperone Insufficiency Links TLR4 Protein Signaling to Endoplasmic Reticulum Stress

Membrane Proteins / Endoplasmic Reticulum Stress / Biological Chemistry / Transcription Factors / Signal Transduction / Toll like receptor signaling / Biological Sciences / Molecular chaperones / RNA interference / Cell line / Humans / Glucose / Mice / Animals / Male / Unfolded Protein Response / Phosphorylation / CHEMICAL SCIENCES / Lipopolysaccharides / Monocytes / Heat Shock Proteins / DNA binding proteins / Immunoblotting / Toll like receptor signaling / Biological Sciences / Molecular chaperones / RNA interference / Cell line / Humans / Glucose / Mice / Animals / Male / Unfolded Protein Response / Phosphorylation / CHEMICAL SCIENCES / Lipopolysaccharides / Monocytes / Heat Shock Proteins / DNA binding proteins / Immunoblotting

Ultrastructural Changes Caused by Snf7 RNAi in Larval Enterocytes of Western Corn Rootworm (Diabrotica virgifera virgifera Le Conte)

Multidisciplinary / RNA interference / Animals / PLoS one / Digestive System / Zea mays / Larva / Enterocytes / Zea mays / Larva / Enterocytes

Deep insights into Dictyocaulus viviparus transcriptomes provides unique prospects for new drug targets and disease intervention

Engineering / Bioinformatics / Technology / Molecular Biology / Caenorhabditis elegans / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling

Deep insights into Dictyocaulus viviparus transcriptomes provides unique prospects for new drug targets and disease intervention

Engineering / Bioinformatics / Technology / Molecular Biology / Caenorhabditis elegans / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling
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