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RNA interference
RNA interference
Hypoxia-Induced Decrease in p53 Protein Level and Increase in c-jun DNA Binding Activity Results in Cancer Cell Resistance
Apoptosis / Western blotting / RNA interference / Humans / Tumor Hypoxia / NF-kappa B / Neoplasia / Transcription Factor / Clinical Sciences / DNA binding / Lactate dehydrogenase / Protein Binding / DNA binding proteins / Induced Resistance / Gene expression profiling / NF-kappa B / Neoplasia / Transcription Factor / Clinical Sciences / DNA binding / Lactate dehydrogenase / Protein Binding / DNA binding proteins / Induced Resistance / Gene expression profiling
Copper(ii) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response
Technology / Oxidative Stress / Metal Nanoparticles / RNA interference / Humans / Copper / Physical sciences / NF-kappa B / Heme Oxygenase / CHEMICAL SCIENCES / Interleukins / Chemokines / Interleukin / Copper / Physical sciences / NF-kappa B / Heme Oxygenase / CHEMICAL SCIENCES / Interleukins / Chemokines / Interleukin
Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells
Extracellular Matrix / RNA interference / Humans / Mice / Animals / Osteonectin
Serotonin Receptors Expressed in Drosophila Mushroom Bodies Differentially Modulate Larval Locomotion
Engineering / Physics / Chemistry / Biology / Locomotion / Drosophila melanogaster / Medicine / Multidisciplinary / RNA interference / Animals / PLoS one / Serotonin Receptors / Larva / FLUOXETINE / Biogenic amines / Mushroom Bodies / Drosophila melanogaster / Medicine / Multidisciplinary / RNA interference / Animals / PLoS one / Serotonin Receptors / Larva / FLUOXETINE / Biogenic amines / Mushroom Bodies
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency
Algorithms / Thermodynamics / RNA / Biotechnology / RNA silencing / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides
Neuron-specific RNA interference using lentiviral vectors
RNA interference / Cell line / Humans / Female / Animals / Lentivirus / Neurons / Clinical Sciences / Rats / Lentivirus / Neurons / Clinical Sciences / Rats
Lentiviral-mediated RNAi in vivo silencing of Col6a1, a gene with complex tissue specific expression pattern
Engineering / Technology / Biotechnology / Apoptosis / Extracellular Matrix / Low Frequency / Transgenic Mice / Biological Sciences / RNA interference / Cell line / Mice / Female / Animals / Male / Lentivirus / Gene expression profiling / Tissue Specificity / Immunoblotting / Low Frequency / Transgenic Mice / Biological Sciences / RNA interference / Cell line / Mice / Female / Animals / Male / Lentivirus / Gene expression profiling / Tissue Specificity / Immunoblotting
Lentiviral-mediated RNAi in vivo silencing of Col6a1, a gene with complex tissue specific expression pattern
Engineering / Technology / Biotechnology / Apoptosis / Extracellular Matrix / Low Frequency / Transgenic Mice / Biological Sciences / RNA interference / Cell line / Mice / Female / Animals / Male / Lentivirus / Gene expression profiling / Tissue Specificity / Immunoblotting / Low Frequency / Transgenic Mice / Biological Sciences / RNA interference / Cell line / Mice / Female / Animals / Male / Lentivirus / Gene expression profiling / Tissue Specificity / Immunoblotting
Nuclear Legumain Activity in Colorectal Cancer
Engineering / Physics / Chemistry / Biology / Immunohistochemistry / Confocal Microscopy / Medicine / Multidisciplinary / RNA interference / Humans / Mutation / Mice / Female / Animals / PLoS one / Cell nucleus / Peer reviewed / Cysteine endopeptidases / Amino Acid Sequence / Lysosomes / Immunoblotting / Confocal Microscopy / Medicine / Multidisciplinary / RNA interference / Humans / Mutation / Mice / Female / Animals / PLoS one / Cell nucleus / Peer reviewed / Cysteine endopeptidases / Amino Acid Sequence / Lysosomes / Immunoblotting
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Genomics / Multidisciplinary / Gene Silencing / Nature / Cell Division / RNA interference / Mitosis / Video microscopy / Humans / Cell Viability / Phenotype / Gene Function / HeLa cells / Very high throughput / Cytokinesis / Cell Proliferation / Cell Survival / RNA interference / Mitosis / Video microscopy / Humans / Cell Viability / Phenotype / Gene Function / HeLa cells / Very high throughput / Cytokinesis / Cell Proliferation / Cell Survival
Transcription Factor Sp3 Represses Expression of p21CIP1 via Inhibition of Productive Elongation by RNA Polymerase II
Transcription Factors / Biological Sciences / RNA interference / Molecular and cellular biology / Humans / Phosphorylation / Histones / Microarray Analysis / HeLa cells / Sumoylation / Gene Expression Regulation / Phosphorylation / Histones / Microarray Analysis / HeLa cells / Sumoylation / Gene Expression Regulation
In vivo trans-specific gene silencing in fungal cells by in planta expression of a double-stranded RNA
Tobacco / Scanning Electron Microscopy / RNA silencing / Gene expression / Gene Silencing / Biological Sciences / RNA interference / Fusarium / Polymerase Chain Reaction / Filamentous fungi / Vascular Plants / double-stranded RNA / Plant Leaves / Biological Sciences / RNA interference / Fusarium / Polymerase Chain Reaction / Filamentous fungi / Vascular Plants / double-stranded RNA / Plant Leaves
The peroxisome proliferator activated receptor regulates malic enzyme gene expression
Immunology / Stem Cells / Kinetics / Mitochondria / Immunology of the Gut / Biological Chemistry / Transcription Factors / Molecular endocrinology / Gene expression / Multidisciplinary / Western blotting / Biological Sciences / DNA / RNA interference / Cell Differentiation / Molecular and cellular biology / Humans / Endothelial Cells / Fatty acids / Mice / G protein-coupled receptors / Animals / Male / Nicotinic Acetylcholine Receptors / RETINOIDS / Adipogenesis / Peroxisome proliferator-activated receptor / Lipid metabolism / Triglycerides / Clinical Sciences / CHEMICAL SCIENCES / Rats / Oxygen / Chromatin Immunoprecipitation / Oral Hypoglycemic Agents / Adipocytes / Peroxisome / Body Weight / Veterinary Sciences / Thiazoles / Base Sequence / Recombinant Proteins / Retinal Diseases / Protein Binding / #Hypolipidemic Agents / Gene Expression Regulation / Biological Chemistry / Transcription Factors / Molecular endocrinology / Gene expression / Multidisciplinary / Western blotting / Biological Sciences / DNA / RNA interference / Cell Differentiation / Molecular and cellular biology / Humans / Endothelial Cells / Fatty acids / Mice / G protein-coupled receptors / Animals / Male / Nicotinic Acetylcholine Receptors / RETINOIDS / Adipogenesis / Peroxisome proliferator-activated receptor / Lipid metabolism / Triglycerides / Clinical Sciences / CHEMICAL SCIENCES / Rats / Oxygen / Chromatin Immunoprecipitation / Oral Hypoglycemic Agents / Adipocytes / Peroxisome / Body Weight / Veterinary Sciences / Thiazoles / Base Sequence / Recombinant Proteins / Retinal Diseases / Protein Binding / #Hypolipidemic Agents / Gene Expression Regulation
LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1
Multidisciplinary / RNA interference / Mice / Circadian Rhythm / Animals / RNA-binding proteins / Amino Acid Sequence / Biological clocks / Cell Cycle Proteins / Gene Expression Regulation / RNA-binding proteins / Amino Acid Sequence / Biological clocks / Cell Cycle Proteins / Gene Expression Regulation
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Genomics / Multidisciplinary / Gene Silencing / Nature / Cell Division / RNA interference / Mitosis / Humans / Cell Viability / Phenotype / Gene Function / HeLa cells / Very high throughput / Cytokinesis / Cell Proliferation / Cell Survival / RNA interference / Mitosis / Humans / Cell Viability / Phenotype / Gene Function / HeLa cells / Very high throughput / Cytokinesis / Cell Proliferation / Cell Survival
Protein kinase C promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor
Stem Cells / Cardiovascular / Gene expression / Western blotting / RNA interference / Cell line / Humans / Endothelial Cells / Polymerase Chain Reaction / Fibroblast Growth Factor / Endothelial cell / Time Factors / Cell Shape / Growth Factor / Protein Kinase Inhibitors / Vascular Endothelial Growth Factor / Cell line / Humans / Endothelial Cells / Polymerase Chain Reaction / Fibroblast Growth Factor / Endothelial cell / Time Factors / Cell Shape / Growth Factor / Protein Kinase Inhibitors / Vascular Endothelial Growth Factor
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