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Pyrazoles
Pyrazoles
Hipertensión pulmonar tromboembólica crónica: tratamiento mediante tromboendarterectomía quirúrgica
Algorithms / Radiology / Praxis / Magnetic Resonance Imaging / Treatment Outcome / Pulmonary Hypertension / Prospective studies / Humans / Hemodynamics / Chronic Disease / Female / Pulmonary Embolism / Male / Follow-up studies / Differential Diagnosis / Radionuclide imaging / Incidence / Thromboembolism / Anticoagulants / Risk factors / Diagnostic Imaging / Recurrence / Clinical Sciences / Angiography / Phosphodiesterase Inhibitors / Aged / Prevalence / Cardiac Catheterization / Middle Aged / Image Enhancement / Adult / Respiratory / Carotid Endarterectomy / Prognosis / Risk Factors / Pyrazoles / Sensitivity and Specificity / X ray Computed Tomography / Medicina Clinica / *Physical Exertion / Blood Flow Velocity / Mechanical Thrombectomy / Contrast Media / Magnetic resonance angiography / Pulmonary circulation / Pulmonary Artery / Postoperative Complications / Pulmonary Hypertension / Prospective studies / Humans / Hemodynamics / Chronic Disease / Female / Pulmonary Embolism / Male / Follow-up studies / Differential Diagnosis / Radionuclide imaging / Incidence / Thromboembolism / Anticoagulants / Risk factors / Diagnostic Imaging / Recurrence / Clinical Sciences / Angiography / Phosphodiesterase Inhibitors / Aged / Prevalence / Cardiac Catheterization / Middle Aged / Image Enhancement / Adult / Respiratory / Carotid Endarterectomy / Prognosis / Risk Factors / Pyrazoles / Sensitivity and Specificity / X ray Computed Tomography / Medicina Clinica / *Physical Exertion / Blood Flow Velocity / Mechanical Thrombectomy / Contrast Media / Magnetic resonance angiography / Pulmonary circulation / Pulmonary Artery / Postoperative Complications
Potential sources of Triatoma infestans reinfesting peridomiciles identified by morphological characterization in Los Llanos, La Rioja, Argentina
Medical Microbiology / Argentina / Insecticides / Female / Animals / Male / Phenotype / Chagas disease / Goats / Chickens / Triatoma / Pyrazoles / Insect Vectors / Male / Phenotype / Chagas disease / Goats / Chickens / Triatoma / Pyrazoles / Insect Vectors
Novel 3‐Carboxy‐and 3‐Phosphonopyrazoline Amino Acids as Potent and Selective NMDA Receptor Antagonists: Design, Synthesis, and Pharmacological Characterization
Organic Chemistry / Mice / Animals / Drug Design / Amino Acids / Rats / Amino Acid Profile / Molecular Conformation / Seizures / Pyrazoles / Neuroprotective Agents / Rats / Amino Acid Profile / Molecular Conformation / Seizures / Pyrazoles / Neuroprotective Agents
Central pharmacological activity of a new piperazine derivative: 4-(1-Phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester
Animal Behavior / Life Sciences / Serotonin / Mice / Animals / Male / Sleep / Time Factors / Pyrazoles / Maze Learning / Pentobarbital / Biochemistry and cell biology / Flumazenil / Male / Sleep / Time Factors / Pyrazoles / Maze Learning / Pentobarbital / Biochemistry and cell biology / Flumazenil
Canonical Transient Receptor Potential 3 Channel Triggers Vascular Endothelial Growth Factor-Induced Intracellular Ca 2+ Oscillations in Endothelial Progenitor Cells Isolated from Umbilical Cord Blood
Physiology / Technology / Stem Cells / Calcium / Signal Transduction / Biological Sciences / RNA interference / Humans / Endothelial Cells / Female / Young Adult / Medical Physiology / Anti-inflammatory agents / Middle Aged / Adult / Cell Proliferation / Pyrazoles / Ion Transport / Biochemistry and cell biology / Biological Sciences / RNA interference / Humans / Endothelial Cells / Female / Young Adult / Medical Physiology / Anti-inflammatory agents / Middle Aged / Adult / Cell Proliferation / Pyrazoles / Ion Transport / Biochemistry and cell biology
A novel antimycobacterial compound acts as an intracellular iron chelator
Microbiology / Medical Microbiology / Siderophores / Iron / Anti-Bacterial Agents / Microbial Sensitivity Tests / Pyrazoles / Microbial Sensitivity Tests / Pyrazoles
Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) as a parasite of pampas deer (Ozoctoceros bezoarticus) and cattle in Brazil\'s Central Pantanal
Microbiology / Brazil / Uruguay / Veterinary Parasitology / Insecticides / Insecticide Resistance / Deer / Female / Animals / Drug Resistance / Fisheries Sciences / Cattle / Larva / Veterinary Sciences / Pyrazoles / Biological Assay / Rhipicephalus (Boophilus) microplus / Rhipicephalus / Insecticide Resistance / Deer / Female / Animals / Drug Resistance / Fisheries Sciences / Cattle / Larva / Veterinary Sciences / Pyrazoles / Biological Assay / Rhipicephalus (Boophilus) microplus / Rhipicephalus
Imidazolopyrazinones as potential antioxidants
Organic Chemistry / Magnetic Resonance Spectroscopy / Antioxidants / Reactive Oxygen Species / Hartree fock method / Imidazoles / Pyrazoles / Structure activity Relationship / Superoxide Anion / Superoxides / Molecular Structure / Imidazoles / Pyrazoles / Structure activity Relationship / Superoxide Anion / Superoxides / Molecular Structure
Canonical Transient Receptor Potential 3 Channel Triggers Vascular Endothelial Growth Factor-Induced Intracellular Ca 2+ Oscillations in Endothelial Progenitor Cells Isolated from Umbilical Cord Blood
Physiology / Technology / Stem Cells / Calcium / Signal Transduction / Biological Sciences / RNA interference / Humans / Endothelial Cells / Female / Young Adult / Medical Physiology / Anti-inflammatory agents / Middle Aged / Adult / Cell Proliferation / Pyrazoles / Ion Transport / Biochemistry and cell biology / Biological Sciences / RNA interference / Humans / Endothelial Cells / Female / Young Adult / Medical Physiology / Anti-inflammatory agents / Middle Aged / Adult / Cell Proliferation / Pyrazoles / Ion Transport / Biochemistry and cell biology
Src Kinase Inhibition Improves Acute Outcomes After Experimental Intracerebral Hemorrhage
Behavior / Treatment Outcome / Enzyme Inhibitors / Apoptosis / Stroke / Glucose Metabolism / Animals / Male / Cell Death / Kinase inhibitor / Clinical Sciences / Apoptose / Src kinase / Rats / Blood Flow / Intracerebral Hemorrhage / Pyrazoles / Cerebral Hemorrhage / Neurosciences / Direct Injection / Matrix Metalloproteinase / Glucose Metabolism / Animals / Male / Cell Death / Kinase inhibitor / Clinical Sciences / Apoptose / Src kinase / Rats / Blood Flow / Intracerebral Hemorrhage / Pyrazoles / Cerebral Hemorrhage / Neurosciences / Direct Injection / Matrix Metalloproteinase
Clinical Pharmacokinetics and Pharmacodynamics of Desloratadine, Fexofenadine and Levocetirizine: A Comparative Review
Nonlinear dynamics / Membrane Proteins / Drug interactions / Therapeutic drug monitoring / Stroke / Pregnancy / Humans / Autoimmune diseases / Clinical Pharmacokinetics / Pharmacogenetics / Female / Organ Transplantation / Intestinal absorption / Myocardial Infarction / Adult / Isoenzymes / Biotransformation / Pyrazoles / Area Under Curve / Pregnancy / Humans / Autoimmune diseases / Clinical Pharmacokinetics / Pharmacogenetics / Female / Organ Transplantation / Intestinal absorption / Myocardial Infarction / Adult / Isoenzymes / Biotransformation / Pyrazoles / Area Under Curve
Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy
Diabetes / Membrane Proteins / Mice / Animals / Male / Polymerase Chain Reaction / Diabetic Nephropathy / Transforming Growth Factor Beta / Albuminuria / Pyrazoles / Piperidines / Cannabinoid Receptor / Polymerase Chain Reaction / Diabetic Nephropathy / Transforming Growth Factor Beta / Albuminuria / Pyrazoles / Piperidines / Cannabinoid Receptor
Cannabinoid CB1 receptor antagonism modulates plasma corticosterone in rodents
Therapeutic drug monitoring / Mice / Animals / Corticosterone / Male / Rats / Time Dependent / Time Factors / Reproducibility of Results / Wistar Rats / Biological markers / Pyrazoles / Knockout Mice / CB 1 receptor / Piperidines / Rats / Time Dependent / Time Factors / Reproducibility of Results / Wistar Rats / Biological markers / Pyrazoles / Knockout Mice / CB 1 receptor / Piperidines
Application of Structure-Based Drug Design and Parallel Chemistry to Identify Selective, Brain Penetrant, In Vivo Active Phosphodiesterase 9A Inhibitors
Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Dogs / Humans / Blood brain barrier / Animals / Drug Design / Rats / Pyrazoles / Structure activity Relationship / cyclic GMP / Molecular Structure / Blood brain barrier / Animals / Drug Design / Rats / Pyrazoles / Structure activity Relationship / cyclic GMP / Molecular Structure
Pyrazolopyrimidines Establish MurC as a Vulnerable Target in Pseudomonas aeruginosa and Escherichia coli
Enzyme Inhibitors / Biological Sciences / Humans / Protein Kinases / Escherichia coli / Pseudomonas aeruginosa / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Alanine / Pyrazoles / Structure activity Relationship / Molecular Structure / Pseudomonas aeruginosa / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Alanine / Pyrazoles / Structure activity Relationship / Molecular Structure
Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors
Humans / Mice / Nitric oxide / Animals / Blood / Male / Arthritis / Vasoconstriction / Platelet activation mechanism / Inflammatory disease / Clinical Sciences / Adverse Event / Side Effect / Pyrazoles / Aorta / Biological Availability / Healthy Subjects / Indomethacin / Male / Arthritis / Vasoconstriction / Platelet activation mechanism / Inflammatory disease / Clinical Sciences / Adverse Event / Side Effect / Pyrazoles / Aorta / Biological Availability / Healthy Subjects / Indomethacin
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