Protein Folding

Intraluminal hydrogen peroxide induces a permeability change of the endoplasmic reticulum membrane

Electron Microscopy / Protein Folding / Endoplasmic Reticulum Stress / Liver / Permeability / Mice / Animals / Male / Glutathione / Endoplasmic Reticulum / ER stress / Hydrogen Peroxide / Ascorbic Acid / Oxidation-Reduction / Low molecular weight / Biochemistry and cell biology / Mice / Animals / Male / Glutathione / Endoplasmic Reticulum / ER stress / Hydrogen Peroxide / Ascorbic Acid / Oxidation-Reduction / Low molecular weight / Biochemistry and cell biology

Structural and mechanistic comparison of prokaryotic and eukaryotic phosphoinositide-specific phospholipases C

Molecular Biology / Protein Folding / Catalysis / Phospholipids / Signal Transduction / Catalytic Mechanism / Crystal structure / Humans / Sequence alignment / Animals / Enzyme / Active site / Rats / Substrate Specificity / Bacillus Cereus / Virulence factor / Amino Acid Sequence / Structural Similarity Index / Second Messengers / Myo-inositol / Pathogenic Bacteria / Biochemistry and cell biology / Phospholipase C / Catalytic Mechanism / Crystal structure / Humans / Sequence alignment / Animals / Enzyme / Active site / Rats / Substrate Specificity / Bacillus Cereus / Virulence factor / Amino Acid Sequence / Structural Similarity Index / Second Messengers / Myo-inositol / Pathogenic Bacteria / Biochemistry and cell biology / Phospholipase C

Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

Protein Folding / Kinetics / Humans / Mutation / Male / Microtubules / Glycolysis / Triosephosphate Isomerase / Biochemistry and cell biology / Pentose Phosphate Pathway / Microtubules / Glycolysis / Triosephosphate Isomerase / Biochemistry and cell biology / Pentose Phosphate Pathway

Design of amino acid sequences to fold into Cα-model proteins

Engineering / Physical Chemistry / Protein Folding / Chemical Physics / Macromolecular X-Ray Crystallography / Humans / Computer Simulation / Lattice Beam Model / Physical sciences / Random Matrix Theory / Proteins / CHEMICAL SCIENCES / Amino Acids / Protein Secondary Structure Prediction / Amino Acid Profile / Molecular Conformation / Protein Conformation / Amino Acid Sequence / Humans / Computer Simulation / Lattice Beam Model / Physical sciences / Random Matrix Theory / Proteins / CHEMICAL SCIENCES / Amino Acids / Protein Secondary Structure Prediction / Amino Acid Profile / Molecular Conformation / Protein Conformation / Amino Acid Sequence

Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

Protein Folding / Kinetics / Humans / Mutation / Male / Microtubules / Glycolysis / Triosephosphate Isomerase / Biochemistry and cell biology / Pentose Phosphate Pathway / Microtubules / Glycolysis / Triosephosphate Isomerase / Biochemistry and cell biology / Pentose Phosphate Pathway

Design of a switchable eliminase

Protein Folding / Catalysis / Multidisciplinary / Computer Simulation / Animals / Chickens / Calmodulin / Amino Acid Substitution Rates / Allosteric regulation / Chickens / Calmodulin / Amino Acid Substitution Rates / Allosteric regulation

Amino acid sequence, biochemical characterization, and comparative modeling of a nonspecific lipid transfer protein from Amaranthus hypochondriacus

Protein Folding / Mass Spectrometry / Lipids / Circular Dichroism / Maize / High Performance Liquid Chromatography / PLANT DEFENSE / High Pressure Liquid Chromatography / Protein Sequence Analysis / Secondary Structure / Amaranthus / Protein Secondary Structure Prediction / Comparative modeling / Molecular Mass / Plant species / Molecular weight / Species Specificity / Amino Acid Sequence / Protein Binding / PLANT PROTEINS / Biochemistry and cell biology / High Performance Liquid Chromatography / PLANT DEFENSE / High Pressure Liquid Chromatography / Protein Sequence Analysis / Secondary Structure / Amaranthus / Protein Secondary Structure Prediction / Comparative modeling / Molecular Mass / Plant species / Molecular weight / Species Specificity / Amino Acid Sequence / Protein Binding / PLANT PROTEINS / Biochemistry and cell biology

Chemical Chaperones Mitigate Experimental Asthma by Attenuating Endoplasmic Reticulum Stress

Protein Folding / Inflammation / Asthma / Endoplasmic Reticulum Stress / Molecular chaperones / Mice / Animals / Male / Unfolded Protein Response / Endoplasmic Reticulum / Trehalose / Lung / Glycerol / Mice / Animals / Male / Unfolded Protein Response / Endoplasmic Reticulum / Trehalose / Lung / Glycerol

Biophysical characterization of a recombinant leucyl aminopeptidase from Bacillus kaustophilus

Biochemistry / Thermodynamics / Dentistry / Structural Biology / Molecular Dynamics Simulation / Genomics / Protein Folding / Proteomics / Biological Physics / Fluorescent Dyes and Reagents / Apoptosis / Structural Genomics / Ion Channels / Macromolecular X-Ray Crystallography / Protein Stability / HIV / Neurospora crassa / Cell line / Humans / Sequence alignment / Computer Simulation / Circular Dichroism / Mice / Animals / Bacillus / Ligand Binding / Temperature / Urea / Enzyme / Molecular cloning / Amino Acids / Protein Sequence Analysis / Cell nucleus / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Success Rate / Spectrum analysis / Trifluoroethanol / Transfection / Protein Conformation / Molecular weight / Large Scale / Amino Acid Sequence / Calcium Chloride / Protein Quaternary Structure / Recombinant Protein / Structure activity Relationship / Recombinant Proteins / Protein Binding / Hydrogen-Ion Concentration / X Ray Crystallography / Structure Determination / Protein Denaturation / Ligands / Sodium Chloride / Biochemistry and cell biology / Solvents / Genomics / Protein Folding / Proteomics / Biological Physics / Fluorescent Dyes and Reagents / Apoptosis / Structural Genomics / Ion Channels / Macromolecular X-Ray Crystallography / Protein Stability / HIV / Neurospora crassa / Cell line / Humans / Sequence alignment / Computer Simulation / Circular Dichroism / Mice / Animals / Bacillus / Ligand Binding / Temperature / Urea / Enzyme / Molecular cloning / Amino Acids / Protein Sequence Analysis / Cell nucleus / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Success Rate / Spectrum analysis / Trifluoroethanol / Transfection / Protein Conformation / Molecular weight / Large Scale / Amino Acid Sequence / Calcium Chloride / Protein Quaternary Structure / Recombinant Protein / Structure activity Relationship / Recombinant Proteins / Protein Binding / Hydrogen-Ion Concentration / X Ray Crystallography / Structure Determination / Protein Denaturation / Ligands / Sodium Chloride / Biochemistry and cell biology / Solvents

Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis

Thermodynamics / Molecular Biology / Protein Folding / Macromolecular X-Ray Crystallography / Molecular / Humans / Mutation / Escherichia coli / Protein structure / Structure Analysis / Anthrax / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Bacillus subtilis / Substrate Specificity / Amino Acid Sequence / Resistance Genes Mechanism) / Bacillus Anthracis / Lethal Factor / Protein Binding / Protein Data Bank / Biochemistry and cell biology / Humans / Mutation / Escherichia coli / Protein structure / Structure Analysis / Anthrax / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Bacillus subtilis / Substrate Specificity / Amino Acid Sequence / Resistance Genes Mechanism) / Bacillus Anthracis / Lethal Factor / Protein Binding / Protein Data Bank / Biochemistry and cell biology

Pharmacological chaperones: potential treatment for conformational diseases

Protein Folding / Treatment / Molecular chaperones / Metabolic Bone Disease / Humans / Metabolic diseases / Clinical Sciences / Chaperone / Metabolic diseases / Clinical Sciences / Chaperone

Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum

Protein Folding / Multidisciplinary / Molecular chaperones / Virulence / Animals / Leishmania infantum / Peroxiredoxins / Leishmania infantum / Peroxiredoxins

Empirical free energy calculation: Comparison to calorimetric data

Thermodynamics / Physical Chemistry / Protein Folding / Protein Science / Molecular Mechanics / Complex System / van der Waals interaction / Protein folding/unfolding / Proteins / Van Der Waals / Free Energy / Evaluation Model / Heat Capacity / Surface Area / Calorimetry / Biochemistry and cell biology / Binding free energy / Complex System / van der Waals interaction / Protein folding/unfolding / Proteins / Van Der Waals / Free Energy / Evaluation Model / Heat Capacity / Surface Area / Calorimetry / Biochemistry and cell biology / Binding free energy

Protein Design Based on Parallel Dimensional Reduction

Computational Chemistry / Combinatorial Optimization / Protein Folding / Protein Design / Proteins / THEORETICAL AND COMPUTATIONAL CHEMISTRY / High performance computer / Dimerization / THEORETICAL AND COMPUTATIONAL CHEMISTRY / High performance computer / Dimerization

Experimental and computational approaches to electrical conductor loading characteristics

Pharmacology / Thermodynamics / Physical Chemistry / Polymorphism / Protein Folding / Drug Discovery / Drug delivery / Rule of Law / Adsorption / Protein Design / Computers / Permeability / High throughput screening / Advanced Drug Delivery Research / Gene Network / Solubility / Free Energy / Protein Function / Biological Network / Biological systems / Molecular weight / Rule Based / Pharmaceutical preparations / Drug Discovery / Drug delivery / Rule of Law / Adsorption / Protein Design / Computers / Permeability / High throughput screening / Advanced Drug Delivery Research / Gene Network / Solubility / Free Energy / Protein Function / Biological Network / Biological systems / Molecular weight / Rule Based / Pharmaceutical preparations

Crystal Structure of Manganese Catalase from Lactobacillus plantarum

Water / Structure / Protein Folding / Calcium / Manganese / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Peroxidase / Glutamate / Lactobacillus / Catalase / Enzyme / CHEMICAL SCIENCES / Hydrogen Peroxide / Active site / Oxygen / Lactobacillus Plantarum / Molecular Replacement / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Peroxidase / Glutamate / Lactobacillus / Catalase / Enzyme / CHEMICAL SCIENCES / Hydrogen Peroxide / Active site / Oxygen / Lactobacillus Plantarum / Molecular Replacement
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