Protease Inhibitors

Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents

Genetics / Microbiology / Medical Microbiology / Drug development / Protein synthesis / Tuberculosis / Mycobacterium tuberculosis / Escherichia coli / Mycobacterium / Mice / Female / Animals / Plasmids / Enzyme / Antibacterial activity / Anti-Bacterial Agents / Buffers / Protease Inhibitors / Antimicrobial agents / Microbial Sensitivity Tests / Culture Media / Recombinant Protein / Drug Targeting / Mycobacterium bovis / Tuberculosis / Mycobacterium tuberculosis / Escherichia coli / Mycobacterium / Mice / Female / Animals / Plasmids / Enzyme / Antibacterial activity / Anti-Bacterial Agents / Buffers / Protease Inhibitors / Antimicrobial agents / Microbial Sensitivity Tests / Culture Media / Recombinant Protein / Drug Targeting / Mycobacterium bovis

Dipeptidyl peptidase 8/9-like activity in human leukocytes

Immunology / Humans / Nitriles / Monoclonal Antibodies / Proline / Specific Activity / Protease Inhibitors / Molecular Conformation / Structure activity Relationship / Enzymatic Activity / Adamantane / Leukocytes / Piperidines / Specific Activity / Protease Inhibitors / Molecular Conformation / Structure activity Relationship / Enzymatic Activity / Adamantane / Leukocytes / Piperidines

A Picomolar Inhibitor of Resistant Strains of Human Immunodeficiency Virus Protease Identified by a Combinatorial Approach

Kinetics / Mutation / HIV protease / Drug Resistance / Drug Design / Enzyme / Human immunodeficiency virus / Protease Inhibitors / Substrate Specificity / Amino Acid Profile / Amino Acid Substitution Rates / Biochemistry and cell biology / Enzyme / Human immunodeficiency virus / Protease Inhibitors / Substrate Specificity / Amino Acid Profile / Amino Acid Substitution Rates / Biochemistry and cell biology

Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation

Kinetics / Biological Sciences / Cell Differentiation / Mice / Animals / Biochemical / Metals / CHEMICAL SCIENCES / Protease Inhibitors / Recombinant Proteins / Biochemical / Metals / CHEMICAL SCIENCES / Protease Inhibitors / Recombinant Proteins

Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation

Kinetics / Biological Sciences / Cell Differentiation / Mice / Animals / Biochemical / Metals / CHEMICAL SCIENCES / Protease Inhibitors / Recombinant Proteins / Biochemical / Metals / CHEMICAL SCIENCES / Protease Inhibitors / Recombinant Proteins

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3

Organic Chemistry / Apoptosis / Cell line / Stroke / Escherichia coli / Signal Transduction Pathway Models / Caspase / Protease Inhibitors / Bioorganic and medicinal Chemistry / Structure activity Relationship / Signal Transduction Pathway Models / Caspase / Protease Inhibitors / Bioorganic and medicinal Chemistry / Structure activity Relationship

Human Leukocyte Elastase Induces Keratinocyte Proliferation In Vitro and In Vivo

Cell Division / Cell line / Humans / Keratinocytes / Mice / Animals / Clinical Sciences / Protease Inhibitors / INVESTIGATIVE / Serine Protease / Animals / Clinical Sciences / Protease Inhibitors / INVESTIGATIVE / Serine Protease

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3

Organic Chemistry / Apoptosis / Cell line / Stroke / Escherichia coli / Signal Transduction Pathway Models / Caspase / Protease Inhibitors / Bioorganic and medicinal Chemistry / Structure activity Relationship / Signal Transduction Pathway Models / Caspase / Protease Inhibitors / Bioorganic and medicinal Chemistry / Structure activity Relationship

Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells

Kidney diseases / Gene expression / Extracellular Matrix / Cell Division / Cell line / Humans / Kidney / Peptides / Fibrosis / Clinical Sciences / mRna expression levels / Anti-Bacterial Agents / Epithelial cells / Time Dependent / Endothelial cell / Protease Inhibitors / Protein Expression / Transforming Growth Factor Beta / Losartan / Tissue Plasminogen Activator / Angiotensin II / Renal Fibrosis / Enzyme Linked Immunosorbent Assay / Plasminogen Activator Inhibitor / Plasminogen Activator / Humans / Kidney / Peptides / Fibrosis / Clinical Sciences / mRna expression levels / Anti-Bacterial Agents / Epithelial cells / Time Dependent / Endothelial cell / Protease Inhibitors / Protein Expression / Transforming Growth Factor Beta / Losartan / Tissue Plasminogen Activator / Angiotensin II / Renal Fibrosis / Enzyme Linked Immunosorbent Assay / Plasminogen Activator Inhibitor / Plasminogen Activator

Cyclic sulfamide γ-secretase inhibitors

Organic Chemistry / Mice / Animals / Protease Inhibitors / Structure activity Relationship / Brain Chemistry / Heterocyclic compounds / Brain Chemistry / Heterocyclic compounds

Synergy between Natriuretic Peptides and Phosphodiesterase 5 Inhibitors Ameliorates Pulmonary Arterial Hypertension

Treatment Outcome / Pulmonary Hypertension / Blood Pressure / Nitric oxide / Animals / Male / Disease Severity / American / Animal Model / Phosphodiesterase Inhibitors / Rats / Protease Inhibitors / Combination drug therapy / Ct Image of Pulmonary Artery / Vascular Reactivity / Vasodilation / cyclic GMP / Vascular Resistance / Atrial Natriuretic Factor / Male / Disease Severity / American / Animal Model / Phosphodiesterase Inhibitors / Rats / Protease Inhibitors / Combination drug therapy / Ct Image of Pulmonary Artery / Vascular Reactivity / Vasodilation / cyclic GMP / Vascular Resistance / Atrial Natriuretic Factor

Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation

Kinetics / Biological Sciences / Cell Differentiation / Mice / Animals / Biochemical / Metals / CHEMICAL SCIENCES / Protease Inhibitors / Recombinant Proteins / Biochemical / Metals / CHEMICAL SCIENCES / Protease Inhibitors / Recombinant Proteins

Antineutrophil cytoplasmic antibodies preferentially engage Fc gammaRIIIb on human neutrophils

Immunology / Cell Adhesion / Immunology of the Gut / Humans / Monoclonal Antibodies / The / Neutrophils / Protease Inhibitors / Substrate Specificity / Protein Binding / Respiratory Burst / The / Neutrophils / Protease Inhibitors / Substrate Specificity / Protein Binding / Respiratory Burst

Relación estructura-función de inhibidores de proteasas tipo BPTI-Kunitz Structure-function relationship of BPTI-Kunitz type protease inhibitors

Protease Inhibitors

Micro y nano-biotecnologías en la detección y caracterización de inhibidores de proteasas de interés biomédico

Protease Inhibitors

inhibidores de proteasas multifuncionales de naturaleza proteica Multifunctional proteases inhibitors of proteic nature

Protease Inhibitors

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