Peptides

Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid

Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid

Biostable β-amino acid PK/PBAN analogs: Agonist and antagonist properties

Physiology / Pest Management / Pheromones / Neuropeptides / Animals / Peptides / Analog / Structural Change / Physiological Response / Neuropeptide Y / Sex Pheromone / Moths / Amino Acid Profile / Angiotensin Converting Enzyme / Biological Assay / Spodoptera littoralis / Peptides / Analog / Structural Change / Physiological Response / Neuropeptide Y / Sex Pheromone / Moths / Amino Acid Profile / Angiotensin Converting Enzyme / Biological Assay / Spodoptera littoralis

Identification and characterization of endoglucanases for fungicidal activity in Anabaena laxa (Cyanobacteria)

Electrophysiology / Immune response / Kinetics / MicroRNA / Mass Spectrometry / Flow Cytometry / Calcium / Biological Chemistry / Fluorescent Dyes and Reagents / RNA silencing / Dendritic Cells / Signal Transduction / Polyamines / Biological Sciences / RNA interference / Dogs / Plant Genome Project / Cell line / Environmental Sciences / Humans / Sequence alignment / Protein Kinases / Applied / Applied Phycology / Animals / Monoclonal Antibodies / Oryza Sativa / Peptides / Dendritic cell / Chemotaxis / Nucleic Acids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Small RNA / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Molecular cloning / Rats / Experimental Medicine / Genomic Library / Amino Acid Profile / SIGNAL PEPTIDE / Amino Acid Sequence / Benzoxazoles / Cell Wall / Open Reading Frame / Recombinant Proteins / Protein Binding / Bacterial Infection / Ligands / Cyclic nucleotide / Protein Kinase Inhibitors / cDNA library / Nucleotides / Gene Expression Regulation / Adenosine Triphosphate / Intracellular Calcium / Tissue Specificity / Host Defense / Flow Cytometry / Calcium / Biological Chemistry / Fluorescent Dyes and Reagents / RNA silencing / Dendritic Cells / Signal Transduction / Polyamines / Biological Sciences / RNA interference / Dogs / Plant Genome Project / Cell line / Environmental Sciences / Humans / Sequence alignment / Protein Kinases / Applied / Applied Phycology / Animals / Monoclonal Antibodies / Oryza Sativa / Peptides / Dendritic cell / Chemotaxis / Nucleic Acids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Small RNA / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Molecular cloning / Rats / Experimental Medicine / Genomic Library / Amino Acid Profile / SIGNAL PEPTIDE / Amino Acid Sequence / Benzoxazoles / Cell Wall / Open Reading Frame / Recombinant Proteins / Protein Binding / Bacterial Infection / Ligands / Cyclic nucleotide / Protein Kinase Inhibitors / cDNA library / Nucleotides / Gene Expression Regulation / Adenosine Triphosphate / Intracellular Calcium / Tissue Specificity / Host Defense

In vivo protein transduction: biologically active intact pep-1-superoxide dismutase fusion protein efficiently protects against ischemic insult

Genetics / Neuronal cell death / Free Radical / Hippocampus / Reactive Oxygen Species / Mice / Animals / Male / Peptides / Protein structure / Brain Ischemia / Neurons / Astrocytes / Epidermis / Superoxide Dismutase / Antioxidant enzyme / Molecular cloning / Amino Acid Profile / Biological activity / Reperfusion injury / Human Disease / Fusion Protein / Full Length Movies / Biochemistry and cell biology / Mice / Animals / Male / Peptides / Protein structure / Brain Ischemia / Neurons / Astrocytes / Epidermis / Superoxide Dismutase / Antioxidant enzyme / Molecular cloning / Amino Acid Profile / Biological activity / Reperfusion injury / Human Disease / Fusion Protein / Full Length Movies / Biochemistry and cell biology

SMAP-29: a potent antibacterial and antifungal peptide from sheep leukocytes

Kinetics / Cystic Fibrosis / Scanning Electron Microscopy / Antibiotic Resistance / Humans / Circular Dichroism / Escherichia coli / Sheep / Cryptococcus Neoformans / Animals / Antimicrobial activity / Staphylococcus aureus / Drug Design / Peptides / Proteins / Pseudomonas aeruginosa / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Antifungal Agents / Pseudomonas Aeruginosa / Protein Conformation / Leukocytes / Methicillin Resistant Staphylococcus Aureus / Blood Proteins / Biochemistry and cell biology / Minimum inhibitory concentration / Hemolysis / Circular Dichroism / Escherichia coli / Sheep / Cryptococcus Neoformans / Animals / Antimicrobial activity / Staphylococcus aureus / Drug Design / Peptides / Proteins / Pseudomonas aeruginosa / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Antifungal Agents / Pseudomonas Aeruginosa / Protein Conformation / Leukocytes / Methicillin Resistant Staphylococcus Aureus / Blood Proteins / Biochemistry and cell biology / Minimum inhibitory concentration / Hemolysis

Identification of protein components in in vivo human acquired enamel pellicle using LC-ESI-MS/MS

Proteomics / Nanotechnology / Biological Sciences / Humans / Female / Male / Peptides / Proteins / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Adult / Dental Pellicle / Amino Acid Sequence / Proteome / Male / Peptides / Proteins / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Adult / Dental Pellicle / Amino Acid Sequence / Proteome

Novel antimicrobial peptides derived from human immunodeficiency virus type 1 and other lentivirus transmembrane proteins

Genetics / Microbiology / Medical Microbiology / Molecular modeling / HIV / Humans / Infectious Disease / Gram Positive / Peptides / Structure Analysis / Antimicrobial Peptide / Protein Sequence Analysis / Human immunodeficiency virus / Spectrum / Gram-negative bacteria / Anti-Bacterial Agents / Secondary Structure / Calmodulin / Antimicrobial agents / Microbial Sensitivity Tests / Amino Acid Profile / Simian Immunodeficiency Virus / Amino Acid Sequence / Antimicrobial photodynamic therapy / Functional Properties / Host Defense / Humans / Infectious Disease / Gram Positive / Peptides / Structure Analysis / Antimicrobial Peptide / Protein Sequence Analysis / Human immunodeficiency virus / Spectrum / Gram-negative bacteria / Anti-Bacterial Agents / Secondary Structure / Calmodulin / Antimicrobial agents / Microbial Sensitivity Tests / Amino Acid Profile / Simian Immunodeficiency Virus / Amino Acid Sequence / Antimicrobial photodynamic therapy / Functional Properties / Host Defense

Novel Antimicrobial Peptides Derived from Human Immunodeficiency Virus Type 1 and Other Lentivirus Transmembrane Proteins

Genetics / Microbiology / Medical Microbiology / Molecular modeling / HIV / Humans / Infectious Disease / Gram Positive / Peptides / Structure Analysis / Antimicrobial Peptide / Protein Sequence Analysis / Human immunodeficiency virus / Spectrum / Gram-negative bacteria / Anti-Bacterial Agents / Secondary Structure / Calmodulin / Antimicrobial agents / Microbial Sensitivity Tests / Amino Acid Profile / Simian Immunodeficiency Virus / Amino Acid Sequence / Antimicrobial photodynamic therapy / Functional Properties / Host Defense / Humans / Infectious Disease / Gram Positive / Peptides / Structure Analysis / Antimicrobial Peptide / Protein Sequence Analysis / Human immunodeficiency virus / Spectrum / Gram-negative bacteria / Anti-Bacterial Agents / Secondary Structure / Calmodulin / Antimicrobial agents / Microbial Sensitivity Tests / Amino Acid Profile / Simian Immunodeficiency Virus / Amino Acid Sequence / Antimicrobial photodynamic therapy / Functional Properties / Host Defense

Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells

Transcription Factors / Biological Sciences / Acute Myeloid Leukemia / Cell Differentiation / Humans / Fusion Proteins / Peptides / Tretinoin / Fusion Protein / DNA binding proteins / Fusion Proteins / Peptides / Tretinoin / Fusion Protein / DNA binding proteins

Identification and characterization of endoglucanases for fungicidal activity in Anabaena laxa (Cyanobacteria)

Electrophysiology / Immune response / Kinetics / MicroRNA / Mass Spectrometry / Flow Cytometry / Calcium / Biological Chemistry / Fluorescent Dyes and Reagents / RNA silencing / Dendritic Cells / Signal Transduction / Polyamines / Biological Sciences / RNA interference / Dogs / Plant Genome Project / Cell line / Environmental Sciences / Humans / Sequence alignment / Protein Kinases / Applied / Applied Phycology / Animals / Monoclonal Antibodies / Oryza Sativa / Peptides / Dendritic cell / Chemotaxis / Nucleic Acids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Small RNA / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Molecular cloning / Rats / Experimental Medicine / Genomic Library / Amino Acid Profile / SIGNAL PEPTIDE / Amino Acid Sequence / Benzoxazoles / Cell Wall / Open Reading Frame / Recombinant Proteins / Protein Binding / Bacterial Infection / Ligands / Cyclic nucleotide / Protein Kinase Inhibitors / cDNA library / Nucleotides / Gene Expression Regulation / Adenosine Triphosphate / Intracellular Calcium / Tissue Specificity / Host Defense / Flow Cytometry / Calcium / Biological Chemistry / Fluorescent Dyes and Reagents / RNA silencing / Dendritic Cells / Signal Transduction / Polyamines / Biological Sciences / RNA interference / Dogs / Plant Genome Project / Cell line / Environmental Sciences / Humans / Sequence alignment / Protein Kinases / Applied / Applied Phycology / Animals / Monoclonal Antibodies / Oryza Sativa / Peptides / Dendritic cell / Chemotaxis / Nucleic Acids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Small RNA / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Molecular cloning / Rats / Experimental Medicine / Genomic Library / Amino Acid Profile / SIGNAL PEPTIDE / Amino Acid Sequence / Benzoxazoles / Cell Wall / Open Reading Frame / Recombinant Proteins / Protein Binding / Bacterial Infection / Ligands / Cyclic nucleotide / Protein Kinase Inhibitors / cDNA library / Nucleotides / Gene Expression Regulation / Adenosine Triphosphate / Intracellular Calcium / Tissue Specificity / Host Defense

A Viral ER-Resident Glycoprotein Inactivates the MHC-Encoded Peptide Transporter

Immunology / Humans / Immunity / Cytomegalovirus / Endoplasmic Reticulum / P-glycoprotein / Antigen Presentation / Peptides / Glycoproteins / Subcellular Localization / RNA-binding proteins / HeLa cells / Transfection / Subcellular Fractions / MHC class I / P-glycoprotein / Antigen Presentation / Peptides / Glycoproteins / Subcellular Localization / RNA-binding proteins / HeLa cells / Transfection / Subcellular Fractions / MHC class I

Trypanocidal and Leishmanicidal Activities of Sesquiterpene Lactones from Ambrosia tenuifolia Sprengel (Asteraceae)

Microbiology / Plant Biology / Medical Microbiology / Argentina / Medicinal Plants / Flavonoids / Lipopolysaccharide / Phytotherapy / Experimental parasitology / Humans / Infrared spectroscopy / Mice / Female / Animals / Natural Product / Male / Penaeus Monodon / Horseshoe crabs / Litopenaeus Vannamei / Peptides / Cyclic peptides / Selection Index / Antimicrobial Peptide / Chagas disease / Sesquiterpenes / T lymphocytes / Pharmaceutical Biology / Experimental / Infrared / Antimicrobial Cationic Peptides / Trypanosoma Cruzi / Cytotoxic Activity / Tritium / Eupatorium / Xenopus laevis / Antimicrobial agents / Mytilus edulis / Cutaneous Leishmaniasis / Veterinary Sciences / Trypanocidal Agents / Flavones / Medicinal Plant / DNA binding proteins / Lactones / Blood cells / Penaeidae / Blood Proteins / Molecular Structure / The American / Hemolysis / Flavonoids / Lipopolysaccharide / Phytotherapy / Experimental parasitology / Humans / Infrared spectroscopy / Mice / Female / Animals / Natural Product / Male / Penaeus Monodon / Horseshoe crabs / Litopenaeus Vannamei / Peptides / Cyclic peptides / Selection Index / Antimicrobial Peptide / Chagas disease / Sesquiterpenes / T lymphocytes / Pharmaceutical Biology / Experimental / Infrared / Antimicrobial Cationic Peptides / Trypanosoma Cruzi / Cytotoxic Activity / Tritium / Eupatorium / Xenopus laevis / Antimicrobial agents / Mytilus edulis / Cutaneous Leishmaniasis / Veterinary Sciences / Trypanocidal Agents / Flavones / Medicinal Plant / DNA binding proteins / Lactones / Blood cells / Penaeidae / Blood Proteins / Molecular Structure / The American / Hemolysis

Theoretical studies on farnesyltransferase: The distances paradox explained

Macromolecular X-Ray Crystallography / Biological Sciences / Mathematical Sciences / Peptides / Zinc / Proteins / Cysteine / Protein Conformation / Structure Function / Proteins / Cysteine / Protein Conformation / Structure Function

Naturally processed measles virus peptide eluted from class II HLA-DRB1*03 recognized by T lymphocytes from human blood

Mass Spectrometry / Virology / Adolescent / Measles Virus / Biological Sciences / Humans / Child / Female / Male / Antigen Presentation / Peptides / T lymphocytes / Amino Acid Sequence / Humans / Child / Female / Male / Antigen Presentation / Peptides / T lymphocytes / Amino Acid Sequence

RNA recognition by designed peptide fusion creates \"artificial\" tRNA synthetase

RNA / Kinetics / Multidisciplinary / Mutation / Escherichia coli / Peptides / Active site / Time Factors / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Protein Binding / aminoacyl-tRNA synthetase / Genetic Code / Nucleic Acid Conformation / Peptides / Active site / Time Factors / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Protein Binding / aminoacyl-tRNA synthetase / Genetic Code / Nucleic Acid Conformation
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