Mutation - Page 7

A Powerful Molecular Engineering Tool Provided Efficient Chlamydomonas Mutants as Bio-Sensing Elements for Herbicides Detection

Free Radicals / Fluorescence / Oxidative Stress / Multidisciplinary / Genetic Engineering / Humans / Mutation / Chlorophyll / Electron Transport / PLoS one / Herbicides / Neutrons / Amino Acid Substitution Rates / Atrazine / Chlamydomonas Reinhardtii / Protons / Biosensing Techniques / Humans / Mutation / Chlorophyll / Electron Transport / PLoS one / Herbicides / Neutrons / Amino Acid Substitution Rates / Atrazine / Chlamydomonas Reinhardtii / Protons / Biosensing Techniques

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Leishmania infantum amastigotes resistant to nitric oxide cytotoxicity: Impact on in vitro parasite developmental cycle and metabolic enzyme activities

Genetics / Apoptosis / Free Radical / Mutation / Mice / Nitric oxide / Female / Animals / Drug Resistance / Potassium / Life Cycle / Enzyme / Lipopolysaccharides / Enzyme activity / Leishmania infantum / Nitrites / Interferon gamma / Nitric oxide / Female / Animals / Drug Resistance / Potassium / Life Cycle / Enzyme / Lipopolysaccharides / Enzyme activity / Leishmania infantum / Nitrites / Interferon gamma

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RDH12 and RPE65, Visual Cycle Genes Causing Leber Congenital Amaurosis, Differ in Disease Expression

Psychophysics / Blindness / Membrane Proteins / Optical coherence tomography / Adolescent / Biological Sciences / Protein Structure and Function / Vision / Humans / Child / Mutation / Retina / Retinal Degeneration / Genes / Middle Aged / Adult / Human Disease / Gene Disruption / Optical Coherence Tomography (OCT) Market / Gene Transfer / Dark Adaptation / Biological Sciences / Protein Structure and Function / Vision / Humans / Child / Mutation / Retina / Retinal Degeneration / Genes / Middle Aged / Adult / Human Disease / Gene Disruption / Optical Coherence Tomography (OCT) Market / Gene Transfer / Dark Adaptation

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Pituitary development: a complex, temporal regulated process dependent on specific transcriptional factors

Endocrinology / Transcription Factors / Animal Production / Signal Transduction / Humans / Mutation / Animals / Clinical Sciences / Pituitary Gland / Veterinary Sciences / Mutation / Animals / Clinical Sciences / Pituitary Gland / Veterinary Sciences

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Comparison of Expression Profiles in Ovarian Epithelium In Vivo and Ovarian Cancer Identifies Novel Candidate Genes Involved in Disease Pathogenesis

Immunohistochemistry / Ovarian Cancer / Multidisciplinary / Humans / Mutation / Mice / Female / Animals / Genetic Association Studies / Gene Dosage / PLoS one / Aged / Middle Aged / Epithelium / Adult / Chromosome segregation / Reproducibility of Results / In Silico / Overall Survival / Adenocarcinoma / Gene expression profiling / Cohort Studies / Estrous cycle / Ovarian Surface Epithelium / Mice / Female / Animals / Genetic Association Studies / Gene Dosage / PLoS one / Aged / Middle Aged / Epithelium / Adult / Chromosome segregation / Reproducibility of Results / In Silico / Overall Survival / Adenocarcinoma / Gene expression profiling / Cohort Studies / Estrous cycle / Ovarian Surface Epithelium

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Local adaptation of an introduced transgenic insect fungal pathogen due to new beneficial mutations

Confocal Microscopy / Multidisciplinary / DNA / Mutation / Animals / Nucleic acid hybridization / Insects / Metarhizium / Nucleic acid hybridization / Insects / Metarhizium

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Gene expression levels influence amino acid usage and evolutionary rates in endosymbiotic bacteria

Genetics / Molecular Evolution / Symbiosis / Gene expression / Mutation / Animals / Bacteria / Insects / GC content / Gene / Codon Usage / Amino Acids / Evolutionary rate / Amino Acid Profile / Codon / Species Specificity / Amino Acid Substitution Rates / Animals / Bacteria / Insects / GC content / Gene / Codon Usage / Amino Acids / Evolutionary rate / Amino Acid Profile / Codon / Species Specificity / Amino Acid Substitution Rates

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Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

Genomics / Multidisciplinary / Signal Transduction / Humans / Mutation / Cluster Analysis / Candida albicans / Host Pathogen Interactions / Candidemia / Nature Communications / Gene Expression Regulation / Case Control Studies / Cluster Analysis / Candida albicans / Host Pathogen Interactions / Candidemia / Nature Communications / Gene Expression Regulation / Case Control Studies

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Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase

Molecular Dynamics Simulation / Kinetics / Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Mutation / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Binding / Nucleotides / Poliovirus / Mutation / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Binding / Nucleotides / Poliovirus

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Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer

Immunohistochemistry / Pancreatic Cancer / Gene expression / Humans / Mutation / Mice / Animals / Oncogene / Mitogen Activated Protein Kinase / Clinical Sciences / Chromatin Immunoprecipitation / Mice / Animals / Oncogene / Mitogen Activated Protein Kinase / Clinical Sciences / Chromatin Immunoprecipitation

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Spontaneous and mitomycin-C-induced micronuclei in human lymphocytes exposed to extremely low frequency pulsed magnetic fields

Kinetics / Flow Cytometry / Aging / Cell Cycle / Lactation / Adolescent / Magnetic field / Cell Division / Biological Sciences / Environmental Sciences / Humans / Child / Electromagnetic Radiation / Mutation / Micronuclei / Cholesterol / Female / Animals / Statistical Significance / Connective tissue / Weaning / Proteins / Triglycerides / Peripheral blood lymphocyte / Magnetics / Rats / Adult / Wistar Rats / Cell Proliferation / Lymphocytes / Environmental / Healthy Subjects / Mutagens / Turner Syndrome / Blood cells / Biochemistry and cell biology / Mitomycin / Somatic Cells / Adolescent / Magnetic field / Cell Division / Biological Sciences / Environmental Sciences / Humans / Child / Electromagnetic Radiation / Mutation / Micronuclei / Cholesterol / Female / Animals / Statistical Significance / Connective tissue / Weaning / Proteins / Triglycerides / Peripheral blood lymphocyte / Magnetics / Rats / Adult / Wistar Rats / Cell Proliferation / Lymphocytes / Environmental / Healthy Subjects / Mutagens / Turner Syndrome / Blood cells / Biochemistry and cell biology / Mitomycin / Somatic Cells

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Adjuvant Effects Elicited by Novel Oligosaccharide Variants of Detoxified Meningococcal Lipopolysaccharides on Neisseria meningitidis Recombinant PorA Protein: A Comparison in Mice

Multidisciplinary / Mutation / Adaptive Immunity / Female / Animals / Immunization / PLoS one / Lipopolysaccharides / Recombinant Proteins / Oligosaccharides / Immunization / PLoS one / Lipopolysaccharides / Recombinant Proteins / Oligosaccharides

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Mitochondrial DNA mutation frequencies in experimentally irradiated compost worms, Eisenia fetida

Radiobiology of Ionizing Radiation / Environmental Biotechnology / Mitochondrial DNA / Mutation / Animals / Polymerase Chain Reaction / Oligochaeta / Sensitivity and Specificity / Biological Assay / Polymerase Chain Reaction / Oligochaeta / Sensitivity and Specificity / Biological Assay

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Exome Sequencing Links Corticospinal Motor Neuron Disease to Common Neurodegenerative Disorders

Science / Multidisciplinary / Transcriptome / Humans / Mutation / Animals / Genetic Association Studies / Neurons / Gene Regulatory Networks / SYNAPSES / Zebrafish / Axons / Nucleotides / Exome / Cohort Studies / Animals / Genetic Association Studies / Neurons / Gene Regulatory Networks / SYNAPSES / Zebrafish / Axons / Nucleotides / Exome / Cohort Studies

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Restoration of Progranulin Expression Rescues Cortical Neuron Generation in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia

Neurogenesis / Gene expression / Transcriptome / Cell line / Cell Differentiation / Humans / Mutation / Neurons / Haploinsufficiency / Phenotype / Time Factors / Frontotemporal Dementia / Biological markers / Neural Stem Cells / Induced Pluripotent Stem Cells / Gene expression profiling / Humans / Mutation / Neurons / Haploinsufficiency / Phenotype / Time Factors / Frontotemporal Dementia / Biological markers / Neural Stem Cells / Induced Pluripotent Stem Cells / Gene expression profiling

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Probiotic features of Lactobacillus plantarum mutant strains

Probiotics / Cytokines / Applied microbiology / Multidisciplinary / Humans / Mutation / Applied Microbiology and Biotechnology / Caco-2 cells / Epithelial cells / Lactobacillus Plantarum / Gastrointestinal Tract / Microbial Viability / Bacterial Adhesion / Mutation / Applied Microbiology and Biotechnology / Caco-2 cells / Epithelial cells / Lactobacillus Plantarum / Gastrointestinal Tract / Microbial Viability / Bacterial Adhesion

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