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Molecular Structure
Molecular Structure
Photosensitized DNA cleavage promoted by amino acidsElectronic Supplementary Information (ESI) available: procedures for TO?peptide syntheses and experimental details for photochemical experiments. See http://www.rsc.org/suppdata/cc/b3/b306008j/
Chemical / Fluorescent Dyes and Reagents / DNA / Escherichia coli / Plasmids / CHEMICAL SCIENCES / Amino Acids / Time Factors / Thiazoles / Quinolines / Molecular Structure / CHEMICAL SCIENCES / Amino Acids / Time Factors / Thiazoles / Quinolines / Molecular Structure
Dipeptidyl aspartyl fluoromethylketones as potent caspase inhibitors: peptidomimetic replacement of the P2 α-amino acid by a α-hydroxy acid
Organic Chemistry / Apoptosis / Humans / Mice / Animals / D-Aspartic Acid / Amino Acids / Spectrum / Amino Acid Profile / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure / Cysteine Proteinase Inhibitors / D-Aspartic Acid / Amino Acids / Spectrum / Amino Acid Profile / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure / Cysteine Proteinase Inhibitors
Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2-cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogs)
Organic Chemistry / Medicinal Chemistry / Pancreas / Animals / Male / Acetylcholine / Rats / Medicinal / Muscle contraction / Transfection / Muscarinic Receptor / Molecular Structure / Ileum / Acetylcholine / Rats / Medicinal / Muscle contraction / Transfection / Muscarinic Receptor / Molecular Structure / Ileum
Crypthophilic Acids A, B, and C: Resin Glycosides from Aerial Parts of Scrophularia crypthophila ⊥
Natural Products / Turkey / Medicinal Plants / Biological Sciences / CHEMICAL SCIENCES / Natural / Glycosides / Molecular Structure / Natural / Glycosides / Molecular Structure
Alkynyl pyrimidines as dual EGFR/ErbB2 kinase inhibitors
Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Humans / Kinase inhibitor / Hydrogen Bond / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Alkynes / Molecular Structure / Receptor Tyrosine Kinase / Hydrogen Bond / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Alkynes / Molecular Structure / Receptor Tyrosine Kinase
RGD Mimetics containing a central hydantoin scaffold: αVβ3 vs αIIbβ3 selectivity requirements
Organic Chemistry / Fibrinogen / Humans / Peptides / Bioorganic and medicinal Chemistry / Imidazoles / Protein Binding / Molecular Structure / Imidazoles / Protein Binding / Molecular Structure
3D-QSAR design of novel antiepileptic sulfamides
Organic Chemistry / Epilepsy / Mice / Female / Animals / Male / Drug Design / Quantitative Structure Activity Relationship / Three Dimensional / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligands / Molecular Structure / Male / Drug Design / Quantitative Structure Activity Relationship / Three Dimensional / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligands / Molecular Structure
Tetrahydro-4-quinolinamines identified as novel P2Y1 receptor antagonists
Organic Chemistry / Humans / Platelet aggregation / High throughput screening / Thrombosis / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure
Tetrahydro-4-Quinolinamines Identified as Novel P2Y1 Receptor Antagonists
Organic Chemistry / Humans / Platelet aggregation / High throughput screening / Thrombosis / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure
Novel cis-directed, four-electron dioxo oxidant
Deuterium / The / CHEMICAL SCIENCES / Molecular Structure
Novel cis-directed, four-electron dioxo oxidant
Deuterium / The / CHEMICAL SCIENCES / Molecular Structure
Protein comparison and classification: a differential geometric approach
Multidisciplinary / Protein structure / Proteins / Mathematical Model / X ray diffraction / Protein Conformation / Organic Compound / Molecular Structure / Protein Conformation / Organic Compound / Molecular Structure
GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo
Cats / Cell line / Humans / Mice / G protein-coupled receptors / Animals / Male / Research Paper / Vasoconstriction / Rats / Radioligand Assay / Benzamides / Molecular Structure / Animals / Male / Research Paper / Vasoconstriction / Rats / Radioligand Assay / Benzamides / Molecular Structure
A carboxylato-supported alkoxo-bridged dimanganese(III) complex: bis(mu-benzoato-O:O\')bis[3-(33-methoxysalicydeneamino)propanolato-O,N,O\':O\']dimanganese(III)
Inorganic Chemistry / Manganese / Macromolecular X-Ray Crystallography / Crystal structure / Enzymes / XRD / Molecular Mimicry / Ether / Organometallic Compounds / Molecular Structure / XRD / Molecular Mimicry / Ether / Organometallic Compounds / Molecular Structure
Design and Photophysical Properties of Zinc(II) Porphyrin-Containing Dendrons Linked to a Central Artificial Special Pair
Fluorescence / Dendrimers / Click chemistry / Copper / Electron Transfer / Zinc / CHEMICAL SCIENCES / Energy Transfer / Phosphorescence / Molecular Structure / Zinc / CHEMICAL SCIENCES / Energy Transfer / Phosphorescence / Molecular Structure
Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †
Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Humans / Cancer Therapy / Mice / Animals / Isoenzymes / Medicinal / Neoplasms / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Mice / Animals / Isoenzymes / Medicinal / Neoplasms / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor
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