Molecular Conformation

Antimalarial Compounds from Rhaphidophora d ecursiva

Natural Products / Medicinal Plants / Vietnam / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / Molecular Conformation / Plant Leaves / Animals / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / Molecular Conformation / Plant Leaves

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Cyclic trihydroxamic acid derivatives

Probability / Macromolecular X-Ray Crystallography / Hydrogen Bonding / Molecular Conformation / Triazines / Acids

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Sesquiterpene Lactones with Potential Use as Natural Herbicide Models (I): trans,trans- Germacranolides

Engineering / Chemistry / Humans / Vegetables / Herbicides / Agricultural / Sesquiterpenes / CHEMICAL SCIENCES / Wild edible plants / Agricultural and Food Chemistry / Molecular Conformation / Structure activity Relationship / Lactones / Lycopersicon esculentum / Molecular Structure / Agricultural / Sesquiterpenes / CHEMICAL SCIENCES / Wild edible plants / Agricultural and Food Chemistry / Molecular Conformation / Structure activity Relationship / Lactones / Lycopersicon esculentum / Molecular Structure

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In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity

Organic Chemistry / Medicinal Chemistry / Obesity / Pharmacokinetics / Pharmaceutical Chemistry / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity

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UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries

Natural Products / Mass Spectrometry / Macromolecular X-Ray Crystallography / Biological Sciences / Arizona / CHEMICAL SCIENCES / Diterpenes / Molecular Conformation / Flavones / Hesperidin / Molecular Structure / Plant Leaves / CHEMICAL SCIENCES / Diterpenes / Molecular Conformation / Flavones / Hesperidin / Molecular Structure / Plant Leaves

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Elemanolide sesquiterpenes and eudesmane sesquiterpene glycosides from Centaurea hierapolitana

Phytochemistry / Mass Spectrometry / Biological Sciences / Sesquiterpenes / CHEMICAL SCIENCES / Structure Elucidation / Molecular Conformation / Flavones / Hydrolysis / Centaurea / Glycosides / Structure Elucidation / Molecular Conformation / Flavones / Hydrolysis / Centaurea / Glycosides

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Antimalarial Compounds from Rhaphidophora d ecursiva

Natural Products / Medicinal Plants / Vietnam / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / Molecular Conformation / Plant Leaves / Animals / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / Molecular Conformation / Plant Leaves

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New vasorelaxant indole alkaloids, villocarines A–D from Uncaria villosa

Organic Chemistry / Calcium / Pharmacognosy / Magnetic Resonance Spectroscopy / Structural Analysis / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves

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γ-Glutamyltranspeptidases: sequence, structure, biochemical properties, and biotechnological applications

Physiology / Biotechnology / Humans / Animals / Clinical Sciences / Glutamine / Molecular Conformation / Amino Acid Sequence / Biochemistry and cell biology / Molecular Sequence Data / Glutamine / Molecular Conformation / Amino Acid Sequence / Biochemistry and cell biology / Molecular Sequence Data

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Antibacterial Diterpenes from Plectranthus ernstii

Natural Products / Macromolecular X-Ray Crystallography / Biological Sciences / CHEMICAL SCIENCES / Great Britain / Anti-Bacterial Agents / Diterpenes / Natural / Microbial Sensitivity Tests / Molecular Conformation / Methicillin Resistant Staphylococcus Aureus / Molecular Structure / Anti-Bacterial Agents / Diterpenes / Natural / Microbial Sensitivity Tests / Molecular Conformation / Methicillin Resistant Staphylococcus Aureus / Molecular Structure

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Novel 3‐Carboxy‐and 3‐Phosphonopyrazoline Amino Acids as Potent and Selective NMDA Receptor Antagonists: Design, Synthesis, and Pharmacological Characterization

Organic Chemistry / Mice / Animals / Drug Design / Amino Acids / Rats / Amino Acid Profile / Molecular Conformation / Seizures / Pyrazoles / Neuroprotective Agents / Rats / Amino Acid Profile / Molecular Conformation / Seizures / Pyrazoles / Neuroprotective Agents

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Microbial Conversion of Partheniol by Calonectria decora

Fungi / Magnetic Resonance Spectroscopy / Bacteria / Sesquiterpenes / Fermentation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Biotransformation / Gas Chromatography/mass Spectrometry / Molecular Conformation / Molecular Structure / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Biotransformation / Gas Chromatography/mass Spectrometry / Molecular Conformation / Molecular Structure

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2-amino-1-propanol versus 1-amino-2-propanol: Valence band and C 1s core-level photoelectron spectra

Engineering / Algorithms / Thermodynamics / Photochemistry / Carbon / PHOTOELECTRON SPECTROSCOPY / Density-functional theory / Chemical Physics / Synchrotron Radiation / Physical sciences / Electronic Structure / CHEMICAL SCIENCES / Electrons / Amino Acids / Spectrum analysis / Functional Group / Amino Acid Profile / Molecular Conformation / Ab Initio Calculation / Isomerism / PHOTOELECTRON SPECTROSCOPY / Density-functional theory / Chemical Physics / Synchrotron Radiation / Physical sciences / Electronic Structure / CHEMICAL SCIENCES / Electrons / Amino Acids / Spectrum analysis / Functional Group / Amino Acid Profile / Molecular Conformation / Ab Initio Calculation / Isomerism

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Novel endoperoxides: Synthesis and activity against Candida species

Organic Chemistry / Antifungal Drugs / Candida / Endoperoxides / Antifungal Agents / Microbial Sensitivity Tests / Molecular Conformation / Bioorganic and medicinal Chemistry / Species Specificity / Structural Similarity Index / Microbial Sensitivity Tests / Molecular Conformation / Bioorganic and medicinal Chemistry / Species Specificity / Structural Similarity Index

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Novel endoperoxides: synthesis and activity against Candida species

Organic Chemistry / Antifungal Drugs / Candida / Endoperoxides / Antifungal Agents / Microbial Sensitivity Tests / Molecular Conformation / Bioorganic and medicinal Chemistry / Species Specificity / Structural Similarity Index / Microbial Sensitivity Tests / Molecular Conformation / Bioorganic and medicinal Chemistry / Species Specificity / Structural Similarity Index

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