Microtubules

Ectopic A-lattice seams destabilize microtubules

Multidisciplinary / Animals / Microtubules / Kinesin / Rats / Guanosine Triphosphate / Surface Properties / Tubulin / Molecular Conformation / Sus Scrofa / Nature Communications / Protein Transport / Guanosine Triphosphate / Surface Properties / Tubulin / Molecular Conformation / Sus Scrofa / Nature Communications / Protein Transport

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

Drosophila melanogaster / Signal Transduction / Biological Sciences / Mitosis / Humans / Animals / Phosphorylation / Microtubules / HeLa cells / Chromosome segregation / Aurora kinases / Animals / Phosphorylation / Microtubules / HeLa cells / Chromosome segregation / Aurora kinases

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

Comparative QSAR modelling of 2-phenylindole-3-carbaldehyde derivatives as potential antimitotic agents

Organic Chemistry / Principal Component Analysis / Pharmaceutical Chemistry / Mitosis / Humans / Drug Design / Regression Analysis / Quantitative Structure Activity Relationship / Microtubules / Surface Area / Molecular Structure / Drug Design / Regression Analysis / Quantitative Structure Activity Relationship / Microtubules / Surface Area / Molecular Structure

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

RNA Processing Bodies, Peroxisomes, Golgi Bodies, Mitochondria, and Endoplasmic Reticulum Tubule Junctions Frequently Pause at Cortical Microtubules

Plant Biology / Plant cell physiology / Mitochondria / Endoplasmic Reticulum / Microtubules / Actin Cytoskeleton / Peroxisomes / Golgi Apparatus / Biochemistry and cell biology / Actin Cytoskeleton / Peroxisomes / Golgi Apparatus / Biochemistry and cell biology

Nuclear Lamin A/C Deficiency Induces Defects in Cell Mechanics, Polarization, and Migration

Rheology / Cell Migration / Wound Healing / Nanoparticles / Biophysical Chemistry / Cytoskeleton / Biological Sciences / Cell Mechanics / Mice / Animals / Physical sciences / Cell Polarity / Microtubules / CHEMICAL SCIENCES / Nuclear envelope / Cell nucleus / Mechanical Stress / Actin Filaments / Cell Motility / Cytoskeleton / Biological Sciences / Cell Mechanics / Mice / Animals / Physical sciences / Cell Polarity / Microtubules / CHEMICAL SCIENCES / Nuclear envelope / Cell nucleus / Mechanical Stress / Actin Filaments / Cell Motility

Comparative QSAR modelling of 2-phenylindole-3-carbaldehyde derivatives as potential antimitotic agents

Organic Chemistry / Chemometrics / Principal Component Analysis / Statistical Analysis / Modeling / Prediction / Pharmaceutical Chemistry / Comparative Study / Topological Index / Mitosis / Factor analysis / Humans / QSAR / Drug Design / Regression Analysis / Quantitative Structure Activity Relationship / Microtubules / Multiple Linear Regression / Surface Area / Regression Model / Molecular Model / Linear Regression / Molecular Structure / Prediction / Pharmaceutical Chemistry / Comparative Study / Topological Index / Mitosis / Factor analysis / Humans / QSAR / Drug Design / Regression Analysis / Quantitative Structure Activity Relationship / Microtubules / Multiple Linear Regression / Surface Area / Regression Model / Molecular Model / Linear Regression / Molecular Structure

Comparative QSAR modelling of 2-phenylindole-3-carbaldehyde derivatives as potential antimitotic agents

Organic Chemistry / Chemometrics / Principal Component Analysis / Statistical Analysis / Modeling / Prediction / Pharmaceutical Chemistry / Comparative Study / Topological Index / Mitosis / Factor analysis / Humans / QSAR / Drug Design / Regression Analysis / Quantitative Structure Activity Relationship / Microtubules / Multiple Linear Regression / Surface Area / Regression Model / Molecular Model / Linear Regression / Molecular Structure / Prediction / Pharmaceutical Chemistry / Comparative Study / Topological Index / Mitosis / Factor analysis / Humans / QSAR / Drug Design / Regression Analysis / Quantitative Structure Activity Relationship / Microtubules / Multiple Linear Regression / Surface Area / Regression Model / Molecular Model / Linear Regression / Molecular Structure

Paclitaxel Affects Cytosolic Calcium Signals by Opening the Mitochondrial Permeability Transition Pore

Kinetics / Fluorescence Microscopy / Mitochondria / Biological Chemistry / Biological Sciences / Permeability / Mice / Pancreas / Animals / Biological / Calcium Signaling / Paclitaxel / Cyclosporine / Microtubules / CHEMICAL SCIENCES / Cell Membrane / Permeability / Mice / Pancreas / Animals / Biological / Calcium Signaling / Paclitaxel / Cyclosporine / Microtubules / CHEMICAL SCIENCES / Cell Membrane
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