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Microdialysis
Microdialysis
Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification
Organic Chemistry / Humans / Animals / Drug Design / Acetylcholine / Microdialysis / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Area Under Curve / Benzamides / Microdialysis / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Area Under Curve / Benzamides
Rat strain differences in peripheral and central serotonin transporter protein expression and function
Psychology / Cognitive Science / Kinetics / Serotonin / Platelet / Hippocampus / Female / Animals / Serotonin Transporter / Peripheral Nervous System / Corticosterone / Male / Central Nervous System / Membrane transport proteins / European / Microdialysis / Rats / Protein Expression / Citalopram / Species Specificity / Protein Binding / Neurosciences / Adrenalectomy / DNA probes / Serotonin Uptake Inhibitors / Hippocampus / Female / Animals / Serotonin Transporter / Peripheral Nervous System / Corticosterone / Male / Central Nervous System / Membrane transport proteins / European / Microdialysis / Rats / Protein Expression / Citalopram / Species Specificity / Protein Binding / Neurosciences / Adrenalectomy / DNA probes / Serotonin Uptake Inhibitors
Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade
Neuropsychopharmacology / Serotonin / Animals / Male / Synaptic Transmission / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor
Intracerebral microdialysis: I. Experimental studies of diffusion kinetics
Kinetics / Dialysis / Concentration / In Vitro / Diffusion / Animals / Method / Male / Temperature / Perfusion / Difusion / Experimental Study / High Pressure Liquid Chromatography / Microdialysis / In Vivo / Rats / Rat / Pharmacological / Brain Chemistry / Pharmacological Methods / Extracellular Space / Animals / Method / Male / Temperature / Perfusion / Difusion / Experimental Study / High Pressure Liquid Chromatography / Microdialysis / In Vivo / Rats / Rat / Pharmacological / Brain Chemistry / Pharmacological Methods / Extracellular Space
Schweres Schädel-Hirn-Trauma
Neurosurgery / Traumatic Brain Injury / Australia / Survival Analysis / Electroencephalography / Adolescent / Critical Care / Emergency Medical Services / Humans / Developing Country / Hyperglycemia / Young Adults / INTENSIVE CARE / Female / World Health Organisation / Resuscitation / Male / Research and Development / Glasgow Coma Scale / Young Adult / Functional impairment / Brain Ischemia / Risk factors / Brain injury / Clinical Sciences / Microdialysis / Aged / Middle Aged / Head injury / Adult / Public health systems and services research / Time Factors / Prognosis / Thrombosis / Oximetry / Risk Factors / Road Traffic / Disease Management / X ray Computed Tomography / Unconsciousness / Brain Function / Intracranial Hypertension / Neurosciences / Intracranial Pressure / Brain Edema / Adolescent / Critical Care / Emergency Medical Services / Humans / Developing Country / Hyperglycemia / Young Adults / INTENSIVE CARE / Female / World Health Organisation / Resuscitation / Male / Research and Development / Glasgow Coma Scale / Young Adult / Functional impairment / Brain Ischemia / Risk factors / Brain injury / Clinical Sciences / Microdialysis / Aged / Middle Aged / Head injury / Adult / Public health systems and services research / Time Factors / Prognosis / Thrombosis / Oximetry / Risk Factors / Road Traffic / Disease Management / X ray Computed Tomography / Unconsciousness / Brain Function / Intracranial Hypertension / Neurosciences / Intracranial Pressure / Brain Edema
Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade
Neuropsychopharmacology / Serotonin / Animals / Male / Synaptic Transmission / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor
In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics
Animal Behavior / Prefrontal Cortex / Nucleus Accumbens / Dopamine / Brain / Humans / Cerebral Cortex / Animals / Male / Central Nervous System / Peptides / Habenula / Neurons / Haloperidol / European / Microdialysis / Molecular cloning / Rats / Neuronal Activity / Guinea Pig / Substance P / Quinolines / Extracellular Space / Medial Prefrontal Cortex / Clinical evaluation / Humans / Cerebral Cortex / Animals / Male / Central Nervous System / Peptides / Habenula / Neurons / Haloperidol / European / Microdialysis / Molecular cloning / Rats / Neuronal Activity / Guinea Pig / Substance P / Quinolines / Extracellular Space / Medial Prefrontal Cortex / Clinical evaluation
Increasing hippocampal acetylcholine levels enhance behavioral performance in an animal model of diencephalic amnesia
Cognitive Science / Animal Behavior / Cognition / Immunohistochemistry / Hippocampus / Learning and Memory / Brain / Animals / Amnesia / Male / Acetylcholinesterase / Animal Model / Acetylcholine / Cholinesterase inhibitors / High Pressure Liquid Chromatography / Microdialysis / Korsakoff Syndrome / Rats / Model System / Limbic System / Neurosciences / Learning and Memory / Brain / Animals / Amnesia / Male / Acetylcholinesterase / Animal Model / Acetylcholine / Cholinesterase inhibitors / High Pressure Liquid Chromatography / Microdialysis / Korsakoff Syndrome / Rats / Model System / Limbic System / Neurosciences
The GABA uptake inhibitor β-alanine reduces pilocarpine-induced tremor and increases extracellular GABA in substantia nigra pars reticulata as measured by microdialysis
Cognitive Science / Dialysis / Animals / Male / Substantia nigra / Tremor / High Pressure Liquid Chromatography / Microdialysis / Rats / Pilocarpine / Neural pathways / Muscarinic Receptor / Statistical Methods for Neuroscience / Neurosciences / Parkinson Disease / Gamma-Aminobutyric Acid / Tremor / High Pressure Liquid Chromatography / Microdialysis / Rats / Pilocarpine / Neural pathways / Muscarinic Receptor / Statistical Methods for Neuroscience / Neurosciences / Parkinson Disease / Gamma-Aminobutyric Acid
5-HT2A and D2 receptor blockade increases cortical DA release via 5-HT1A receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release
Neurochemistry / Dopamine / Vitamin D receptor / Cerebral Cortex / Animals / Male / Benzodiazepines / High Pressure Liquid Chromatography / Microdialysis / Serotonin Receptors / Rats / RISPERIDONE / Pyridines / Atypical Antipsychotics / Amphetamines / Neurosciences / Serotonin Uptake Inhibitors / Male / Benzodiazepines / High Pressure Liquid Chromatography / Microdialysis / Serotonin Receptors / Rats / RISPERIDONE / Pyridines / Atypical Antipsychotics / Amphetamines / Neurosciences / Serotonin Uptake Inhibitors
Increase in cerebral aerobic metabolism by normobaric hyperoxia after traumatic brain injury
Neurosurgery / Treatment Outcome / Humans / Near Infrared Spectroscopy / Female / Male / Clinical Sciences / Microdialysis / Middle Aged / Adult / Hyperoxia / Lactic Acid / Oxygen Consumption / Neurosciences / Oxidation-Reduction / Male / Clinical Sciences / Microdialysis / Middle Aged / Adult / Hyperoxia / Lactic Acid / Oxygen Consumption / Neurosciences / Oxidation-Reduction
Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification
Organic Chemistry / Humans / Animals / Drug Design / Acetylcholine / Microdialysis / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Area Under Curve / Benzamides / Microdialysis / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Area Under Curve / Benzamides
Angiotensin II type 1 receptor blockade corrects cutaneous nitric oxide deficit in postural tachycardia syndrome
Physiology / Research Design / Treatment Outcome / Enzyme Inhibitors / Adolescent / Humans / Nitric oxide / Female / Heart rate / American / Skin / Medical Physiology / Posture / Clinical Sciences / Microdialysis / Adult / Nitric Oxide Synthase / Time Factors / Leg / Losartan / Vasodilation / Blood Flow Velocity / Syndrome / Neurosciences / *Hot Temperature / Laser Doppler Flowmetry / Tachycardia / Vascular Resistance / Humans / Nitric oxide / Female / Heart rate / American / Skin / Medical Physiology / Posture / Clinical Sciences / Microdialysis / Adult / Nitric Oxide Synthase / Time Factors / Leg / Losartan / Vasodilation / Blood Flow Velocity / Syndrome / Neurosciences / *Hot Temperature / Laser Doppler Flowmetry / Tachycardia / Vascular Resistance
Neuronal activity regulates extracellular tau in vivo
Physiology / Kinetics / Electroencephalography / Biological Sciences / Brain / Mice / Female / Animals / Male / Synaptic Transmission / Medical Physiology / Neurons / Tauopathies / Shell Half-Life / Microdialysis / Analysis of Variance / Experimental Medicine / Tetrodotoxin / Enzyme Linked Immunosorbent Assay / Extracellular Space / Glutamic Acid / Mice / Female / Animals / Male / Synaptic Transmission / Medical Physiology / Neurons / Tauopathies / Shell Half-Life / Microdialysis / Analysis of Variance / Experimental Medicine / Tetrodotoxin / Enzyme Linked Immunosorbent Assay / Extracellular Space / Glutamic Acid
Dizocilpine (MK-801) elicits a tetrodotoxinsensitive increase in extracellular release of dopamine in rat medial frontal cortex
Neurochemistry / Serotonin / Dopamine / Animals / Male / Frontal Cortex / Microdialysis / Rats / Wistar Rats / Tetrodotoxin / Neurosciences / Frontal Lobe / Extracellular Space / Frontal Cortex / Microdialysis / Rats / Wistar Rats / Tetrodotoxin / Neurosciences / Frontal Lobe / Extracellular Space
Medial prefrontal transection enhances social interaction
Cognitive Science / Social Interaction / Prefrontal Cortex / Nucleus Accumbens / Dopamine / Social behavior / Glutamate / Brain / Animals / Male / Amphetamine / Animal Model / Interpersonal Relations / Microdialysis / Rats / Time Factors / Wistar Rats / Social Behavior / Diazepam / Neurosciences / Glutamic Acid / Dextroamphetamine / Gamma-Aminobutyric Acid / Medial Prefrontal Cortex / Motor activity / Glutamate release / Social behavior / Glutamate / Brain / Animals / Male / Amphetamine / Animal Model / Interpersonal Relations / Microdialysis / Rats / Time Factors / Wistar Rats / Social Behavior / Diazepam / Neurosciences / Glutamic Acid / Dextroamphetamine / Gamma-Aminobutyric Acid / Medial Prefrontal Cortex / Motor activity / Glutamate release
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