Mice

Systematic amino acid substitutions improved efficiency of GD2-peptide mimotope vaccination against neuroblastoma

Cancer / Treatment / Prevention / Cancer Vaccines / Humans / Mice / Female / Animals / Vaccination / Efficiency / Neuroblastoma / Molecular Mimicry / Spot / Substitution / Amino Acid Substitution Rates / Gangliosides / immunoglobulin G / Mice / Female / Animals / Vaccination / Efficiency / Neuroblastoma / Molecular Mimicry / Spot / Substitution / Amino Acid Substitution Rates / Gangliosides / immunoglobulin G

Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification

Stem Cells / Wound Healing / Cell Cycle / Stem Cell / Cell Division / Biological Sciences / Cell Differentiation / Keratinocytes / Mice / Female / Animals / Cell / Male / Epidermis / Steady state / Mechanical Stress / Homeostasis / Cell Proliferation / Hair Follicle / Epidermal Stem Cells / Cell Size / Biological Sciences / Cell Differentiation / Keratinocytes / Mice / Female / Animals / Cell / Male / Epidermis / Steady state / Mechanical Stress / Homeostasis / Cell Proliferation / Hair Follicle / Epidermal Stem Cells / Cell Size

Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification

Stem Cells / Wound Healing / Cell Cycle / Stem Cell / Cell Division / Biological Sciences / Cell Differentiation / Keratinocytes / Mice / Female / Animals / Cell / Male / Epidermis / Steady state / Mechanical Stress / Homeostasis / Cell Proliferation / Hair Follicle / Epidermal Stem Cells / Cell Size / Biological Sciences / Cell Differentiation / Keratinocytes / Mice / Female / Animals / Cell / Male / Epidermis / Steady state / Mechanical Stress / Homeostasis / Cell Proliferation / Hair Follicle / Epidermal Stem Cells / Cell Size

Lipin Expression Preceding Peroxisome Proliferator-activated Receptor  Is Critical for Adipogenesis in Vivo and in Vitro

Obesity / Diet / Biological Chemistry / Transcription Factors / Biological Sciences / Adipose tissue / Cell Differentiation / Phosphatidate Phosphatase / Mice / Animals / Male / Peroxisome proliferator-activated receptor / T cells / Lipid metabolism / CHEMICAL SCIENCES / Oral Hypoglycemic Agents / Adipocytes / Gene Expression Regulation / Lipodystrophy / Dietary fats / Adipose tissue / Cell Differentiation / Phosphatidate Phosphatase / Mice / Animals / Male / Peroxisome proliferator-activated receptor / T cells / Lipid metabolism / CHEMICAL SCIENCES / Oral Hypoglycemic Agents / Adipocytes / Gene Expression Regulation / Lipodystrophy / Dietary fats

Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Deficiency Reduces Leukocyte Infiltration into Adipose Tissue and Favors Fat Deposition

Obesity / Skeletal muscle biology / Diabetes / Flow Cytometry / Enzyme Inhibitors / Insulin Resistance / Adipose tissue / Humans / Glucose / Blood Glucose / Insulin / Diabetes mellitus / Amines / Mice / Animals / Blood / Male / Plasma / Deposition / Phosphorylation / Phosphotyrosine / Cattle / Rats / Infiltration / Substrate Specificity / Deficiency / Adipocytes / Fat / Wistar Rats / Type 2 Diabetes Mellitus / Deficit / Recombinant Proteins / Alzheimer Disease / Protein Tyrosine Phosphatases / Monoamine oxidase / Leukocytes / Semicarbazide / Amine / islets of Langerhans / Cell Adhesion Molecules / The American / Insulin Resistance / Adipose tissue / Humans / Glucose / Blood Glucose / Insulin / Diabetes mellitus / Amines / Mice / Animals / Blood / Male / Plasma / Deposition / Phosphorylation / Phosphotyrosine / Cattle / Rats / Infiltration / Substrate Specificity / Deficiency / Adipocytes / Fat / Wistar Rats / Type 2 Diabetes Mellitus / Deficit / Recombinant Proteins / Alzheimer Disease / Protein Tyrosine Phosphatases / Monoamine oxidase / Leukocytes / Semicarbazide / Amine / islets of Langerhans / Cell Adhesion Molecules / The American

Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats

Obesity / Skeletal muscle biology / Diabetes / Flow Cytometry / Enzyme Inhibitors / Insulin Resistance / Adipose tissue / Humans / Glucose / Blood Glucose / Insulin / Diabetes mellitus / Amines / Mice / Animals / Blood / Male / Plasma / Deposition / Phosphorylation / Phosphotyrosine / Cattle / Rats / Infiltration / Substrate Specificity / Deficiency / Adipocytes / Fat / Wistar Rats / Type 2 Diabetes Mellitus / Deficit / Recombinant Proteins / Alzheimer Disease / Protein Tyrosine Phosphatases / Monoamine oxidase / Leukocytes / Semicarbazide / Amine / islets of Langerhans / Cell Adhesion Molecules / The American / Insulin Resistance / Adipose tissue / Humans / Glucose / Blood Glucose / Insulin / Diabetes mellitus / Amines / Mice / Animals / Blood / Male / Plasma / Deposition / Phosphorylation / Phosphotyrosine / Cattle / Rats / Infiltration / Substrate Specificity / Deficiency / Adipocytes / Fat / Wistar Rats / Type 2 Diabetes Mellitus / Deficit / Recombinant Proteins / Alzheimer Disease / Protein Tyrosine Phosphatases / Monoamine oxidase / Leukocytes / Semicarbazide / Amine / islets of Langerhans / Cell Adhesion Molecules / The American

miR-Sens--a retroviral dual-luciferase reporter to detect microRNA activity in primary cells

RNA / Gene expression / Cell line / Humans / Mice / Animals / Gene Order / microRNAs / Base Sequence / Poly A / Protein Biosynthesis / Biochemistry and cell biology / Molecular Sequence Data / Animals / Gene Order / microRNAs / Base Sequence / Poly A / Protein Biosynthesis / Biochemistry and cell biology / Molecular Sequence Data

An estrogen receptor chimera senses ligands by nuclear translocation

Biochemistry / Fluorescence Microscopy / Drug Discovery / Fluorescent Dyes and Reagents / STEROIDS / High Content Screening / Estrogen Receptor / Cercopithecus aethiops / Dexamethasone / Cell line / Humans / Mice / Animals / Immunoprecipitation / Tamoxifen / Time Factors / Transfection / Protein Binding / Cytoplasm / Ligands / Glucocorticoids / Estradiol / Protein Transport / Biochemistry and cell biology / High Content Screening / Estrogen Receptor / Cercopithecus aethiops / Dexamethasone / Cell line / Humans / Mice / Animals / Immunoprecipitation / Tamoxifen / Time Factors / Transfection / Protein Binding / Cytoplasm / Ligands / Glucocorticoids / Estradiol / Protein Transport / Biochemistry and cell biology

Suppression of dsDNA-specific B lymphocytes reduces disease symptoms in SCID model of mouse lupus

Immunology / Autoimmunity / Signal Transduction / DNA / Humans / Systemic Lupus Erythematosus / Mice / Female / Animals / Male / Monoclonal Antibodies / Peptides / T lymphocytes / B Lymphocytes / Cell Proliferation / Adoptive Transfer / Systemic Lupus Erythematosus / Mice / Female / Animals / Male / Monoclonal Antibodies / Peptides / T lymphocytes / B Lymphocytes / Cell Proliferation / Adoptive Transfer

Reducción de la masa muscular mediada por miostatina en un modelo experimental de enfisema pulmonar

Skeletal muscle biology / Oxidative Stress / Antioxidants / Spinal Muscular Atrophy / Mice / Weight Loss / Animals / Male / NF-kappa B / Clinical Sciences / Respiratory Muscles / Muscle development / Signaling pathways / Myostatin / Weight Loss / Animals / Male / NF-kappa B / Clinical Sciences / Respiratory Muscles / Muscle development / Signaling pathways / Myostatin

DNA damaging agents improve stable gene transfer efficiency in mammalian cells

Radiation / DNA damage / Cell line / Humans / Mice / Animals / Gene transfer techniques / Hydrogen Peroxide / Transfection / Recombination / Gene Transfer / Animals / Gene transfer techniques / Hydrogen Peroxide / Transfection / Recombination / Gene Transfer

Bacterially expressed full-length recombinant Plasmodium falciparum RH5 protein binds erythrocytes and elicits potent strain-transcending parasite-neutralizing antibodies

Biological Sciences / Infection and immunity / Escherichia coli / Mice / Animals / Host-parasite interactions / Immune Evasion / Plasmodium falciparum / Erythrocytes / Recombinant Proteins / Protein Binding / Malaria Vaccines / Host-parasite interactions / Immune Evasion / Plasmodium falciparum / Erythrocytes / Recombinant Proteins / Protein Binding / Malaria Vaccines

Loss of Prion Protein in a Transgenic Model of Amyotrophic Lateral Sclerosis

Cognitive Science / Protein Folding / Skeletal muscle biology / Motor neuron / Transgenic Mice / Amyotrophic Lateral Sclerosis / Molecular chaperones / Molecular and cellular biology / Genetic Testing / Mutation / Mice / Animals / Spinal Cord / Superoxide Dismutase / Western blot / Sciatic Nerve / Cellular and Molecular Neuroscience / Enzymatic Activity / Neurosciences / Down-Regulation / Prion Protein / DNA mutational analysis / Amyotrophic Lateral Sclerosis / Molecular chaperones / Molecular and cellular biology / Genetic Testing / Mutation / Mice / Animals / Spinal Cord / Superoxide Dismutase / Western blot / Sciatic Nerve / Cellular and Molecular Neuroscience / Enzymatic Activity / Neurosciences / Down-Regulation / Prion Protein / DNA mutational analysis

3β-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes

Biological Sciences / Insulin Resistance / Humans / Glucose / Blood Glucose / Glucose Metabolism / Mice / Animals / Physical sciences / T cells / Glucose Transport / Plant extracts / Adipocytes / Mangifera indica / Type 2 Diabetes Mellitus / Glucose Uptake / Cell Survival / Glycogen / Oleanolic acid / Biochemistry and cell biology / Glucose Metabolism / Mice / Animals / Physical sciences / T cells / Glucose Transport / Plant extracts / Adipocytes / Mangifera indica / Type 2 Diabetes Mellitus / Glucose Uptake / Cell Survival / Glycogen / Oleanolic acid / Biochemistry and cell biology

3β-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes

Biological Sciences / Insulin Resistance / Humans / Glucose / Blood Glucose / Glucose Metabolism / Mice / Animals / Physical sciences / T cells / Glucose Transport / Plant extracts / Adipocytes / Mangifera indica / Type 2 Diabetes Mellitus / Glucose Uptake / Cell Survival / Glycogen / Oleanolic acid / Biochemistry and cell biology / Glucose Metabolism / Mice / Animals / Physical sciences / T cells / Glucose Transport / Plant extracts / Adipocytes / Mangifera indica / Type 2 Diabetes Mellitus / Glucose Uptake / Cell Survival / Glycogen / Oleanolic acid / Biochemistry and cell biology

3β-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes

Biological Sciences / Insulin Resistance / Humans / Glucose / Blood Glucose / Glucose Metabolism / Mice / Animals / Physical sciences / T cells / Glucose Transport / Plant extracts / Adipocytes / Mangifera indica / Type 2 Diabetes Mellitus / Glucose Uptake / Cell Survival / Glycogen / Oleanolic acid / Biochemistry and cell biology / Glucose Metabolism / Mice / Animals / Physical sciences / T cells / Glucose Transport / Plant extracts / Adipocytes / Mangifera indica / Type 2 Diabetes Mellitus / Glucose Uptake / Cell Survival / Glycogen / Oleanolic acid / Biochemistry and cell biology
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