Human Fibroblasts - Page 8

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

Physiology / Oxidative Stress / Signal Transduction / Humans / Tissue culture / Animals / Male / Cytochrome C / Medical Physiology / Methylene Blue / Cadmium / Enzyme / Hydrogen Peroxide / Mitochondrial dysfunction / Rats / Oxygen / Time Factors / Human Fibroblasts / Alzheimer Disease / Life Span / Oxygen Consumption / Oxidation-Reduction / Oxidants / Biochemistry and cell biology / Thioredoxin reductase / Enzyme Induction / Animals / Male / Cytochrome C / Medical Physiology / Methylene Blue / Cadmium / Enzyme / Hydrogen Peroxide / Mitochondrial dysfunction / Rats / Oxygen / Time Factors / Human Fibroblasts / Alzheimer Disease / Life Span / Oxygen Consumption / Oxidation-Reduction / Oxidants / Biochemistry and cell biology / Thioredoxin reductase / Enzyme Induction

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Deoxycholic acid activates protein kinase C and phospholipase C via increased Ca2+ entry at plasma membrane

Gastroenterology / Calcium / Membrane Proteins / Cell line / Humans / Calcium Signaling / Clinical Sciences / Caco-2 cells / Isoenzymes / Fluorescent Protein / Human Fibroblasts / Cytoplasm / Neurosciences / Plasma Membrane / Phospholipase C / Calcium Signaling / Clinical Sciences / Caco-2 cells / Isoenzymes / Fluorescent Protein / Human Fibroblasts / Cytoplasm / Neurosciences / Plasma Membrane / Phospholipase C

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Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency

Genetics / Gene expression / Human / Humans / Mice / Animals / Clinical Sciences / Human Fibroblasts / Structure activity Relationship / Hexosamines / Animals / Clinical Sciences / Human Fibroblasts / Structure activity Relationship / Hexosamines

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Intramyocardial transplantation of fibroblasts expressing vascular endothelial growth factor attenuates cardiac dysfunction

Gene Therapy / Biological Sciences / Cell therapy / Fibrin / Animals / Male / Cell Transplantation / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Vascular Endothelial Growth Factor / Male / Cell Transplantation / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Vascular Endothelial Growth Factor

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Peroxisomal D-bifunctional protein deficiency: Three adults diagnosed by whole-exome sequencing

Cognitive Science / Neurology / Humans / Fatty acids / Female / Male / Siblings / Clinical Sciences / Adult / Human Fibroblasts / Neurosciences / Exome / Male / Siblings / Clinical Sciences / Adult / Human Fibroblasts / Neurosciences / Exome

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Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice

Stem Cells / DNA damage / DNA repair / Stem Cell / Multidisciplinary / Mitosis / Cell line / Mice / Animals / Bone marrow / PLoS one / Epithelial cells / Radiation Dose / DNA damage response / Gene Targeting / Chromosome segregation / Gastrointestinal Tract / Homologous Recombination / Human Fibroblasts / Cell Cycle Proteins / Cell Survival / Radiation Tolerance / Whole Body / Functional Status / Bone Marrow Cells / Mitomycin / Mitosis / Cell line / Mice / Animals / Bone marrow / PLoS one / Epithelial cells / Radiation Dose / DNA damage response / Gene Targeting / Chromosome segregation / Gastrointestinal Tract / Homologous Recombination / Human Fibroblasts / Cell Cycle Proteins / Cell Survival / Radiation Tolerance / Whole Body / Functional Status / Bone Marrow Cells / Mitomycin

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MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

Kinetics / Cellular Reprogramming / Multidisciplinary / Nature / Cell line / Cell Differentiation / Humans / Mice / Animals / Alternative splicing / Embryonic Stem Cells / RNA-binding proteins / HeLa cells / Alternative Splicing / Induced Pluripotent Stem Cells / Human Fibroblasts / DNA binding proteins / Cell Differentiation / Humans / Mice / Animals / Alternative splicing / Embryonic Stem Cells / RNA-binding proteins / HeLa cells / Alternative Splicing / Induced Pluripotent Stem Cells / Human Fibroblasts / DNA binding proteins

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Hypoxia Enhances the Angiogenic Potential of Human Dental Pulp Cells

Dentistry / Nonparametric Statistics / Regeneration / Adult Stem Cells / Stem Cell / Tissue Regeneration / Signal Transduction / Humans / Vascular endothelium / Endodontics / Human Fibroblasts / Tissue Regeneration / Signal Transduction / Humans / Vascular endothelium / Endodontics / Human Fibroblasts

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Failure of Postnatal Ductus Arteriosus Closure in Prostaglandin Transporter-Deficient Mice

Signal Transduction / Pregnancy / Mice / Female / Animals / Lung / Clinical Sciences / Public health systems and services research / Circulation / Human Fibroblasts / Ductus Arteriosus / Indomethacin / Lung / Clinical Sciences / Public health systems and services research / Circulation / Human Fibroblasts / Ductus Arteriosus / Indomethacin

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A stereoselective anomaly in dicarboxylic amino acid transport

Biological Chemistry / Biological Sciences / Humans / Liver / Animals / The / D-Aspartic Acid / CHEMICAL SCIENCES / Rats / Sodium / Cysteine / Human Fibroblasts / Hydrogen-Ion Concentration / Glutamic Acid / The / D-Aspartic Acid / CHEMICAL SCIENCES / Rats / Sodium / Cysteine / Human Fibroblasts / Hydrogen-Ion Concentration / Glutamic Acid

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Demonstration of intact intracellular cholesterol esterification and normal low-density lipoprotein pathway in fibroblasts from a patient with lecithin:cholesterol acyltransferase deficiency

Biological Sciences / Cell line / Humans / Physical sciences / Human Fibroblasts / Low Density Lipoprotein (LDL)

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Human Cytomegalovirus Elicits a Coordinated Cellular Antiviral Response via Envelope Glycoprotein B

Virology / Transcription Regulation / Transcription Factors / Signal Transduction / Biological Sciences / Humans / Endothelial Cells / Cytomegalovirus / Transcription Factor / Endothelial cell / Cytomegalovirus Infections / Human Fibroblasts / Cell Surface Markers / DNA binding proteins / Antiviral Agents / Gene Expression Regulation / Interferon Alpha / Humans / Endothelial Cells / Cytomegalovirus / Transcription Factor / Endothelial cell / Cytomegalovirus Infections / Human Fibroblasts / Cell Surface Markers / DNA binding proteins / Antiviral Agents / Gene Expression Regulation / Interferon Alpha

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Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation

Calcium / Mitochondria / Biological Sciences / Mice / Animals / Human Molecular Genetics / Endoplasmic Reticulum / Human Fibroblasts / Human Molecular Genetics / Endoplasmic Reticulum / Human Fibroblasts

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Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells

DNA damage / Apoptosis / RNA interference / Humans / Data Collection / Biochemical / Colon cancer / Biological Process / BIOCHEMICAL PHARMACOLOGY / Human Fibroblasts / Antineoplastic Agents / Biochemical / Colon cancer / Biological Process / BIOCHEMICAL PHARMACOLOGY / Human Fibroblasts / Antineoplastic Agents

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V(D)J targeting mistakes occur at low frequency in acute lymphoblastic leukemia

Low Frequency / Mice / Animals / Genes / Metalloproteins / Genetic Recombination / Human Fibroblasts / DNA binding proteins / Acute Lymphoblastic Leukemia / Genetic Recombination / Human Fibroblasts / DNA binding proteins / Acute Lymphoblastic Leukemia

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d-3-Hydroxyacyl-CoA Dehydratase/d-3-Hydroxyacyl-CoA Dehydrogenase Bifunctional Protein Deficiency: A Newly Identified Peroxisomal Disorder

Japan / Biological Sciences / Humans / Liver / Fatty acids / Female / Polymerase Chain Reaction / Infant / Fluorescent Antibody Technique / Consanguinity / Multienzyme complexes / Human Fibroblasts / Oxidation-Reduction / The American / Female / Polymerase Chain Reaction / Infant / Fluorescent Antibody Technique / Consanguinity / Multienzyme complexes / Human Fibroblasts / Oxidation-Reduction / The American

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