Human Disease

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

Mitochondria / Apoptosis / Caspases / Antibodies / Humans / Liver / Mice / Animals / Caspase / Hepatocytes / Human Disease / Hemorrhage / Gamma Irradiation / Liver / Mice / Animals / Caspase / Hepatocytes / Human Disease / Hemorrhage / Gamma Irradiation

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis

Electron Microscopy / Skeletal muscle biology / Gene Therapy / Immunohistochemistry / Confocal Microscopy / Brain / Female / Animals / Disease Severity / Electromyography / Synaptic Transmission / Fluorescent Antibody Technique / Rats / Myasthenia Gravis / Human Disease / Action Potentials / Individual Difference / Neuromuscular Junction / Radioimmunoassay / Brain / Female / Animals / Disease Severity / Electromyography / Synaptic Transmission / Fluorescent Antibody Technique / Rats / Myasthenia Gravis / Human Disease / Action Potentials / Individual Difference / Neuromuscular Junction / Radioimmunoassay

A diet-induced mouse model for glutaric aciduria type I

Magnetic Resonance Imaging / Diet / Survival Analysis / Brain / Mice / Blood brain barrier / Female / Animals / Plant tissue Culture Techniques / Male / Astrocyte / Animal Model / Neurons / Mouse Model / Lysine / Subarachnoid haemorrhage / Human Disease / Dietary Protein / High-protein Diet / Autosomal Recessive / White Matter Lesions / Blood brain barrier / Female / Animals / Plant tissue Culture Techniques / Male / Astrocyte / Animal Model / Neurons / Mouse Model / Lysine / Subarachnoid haemorrhage / Human Disease / Dietary Protein / High-protein Diet / Autosomal Recessive / White Matter Lesions

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis

Electron Microscopy / Skeletal muscle biology / Gene Therapy / Immunohistochemistry / Confocal Microscopy / Brain / Female / Animals / Disease Severity / Electromyography / Synaptic Transmission / Fluorescent Antibody Technique / Rats / Myasthenia Gravis / Human Disease / Action Potentials / Individual Difference / Neuromuscular Junction / Radioimmunoassay / Brain / Female / Animals / Disease Severity / Electromyography / Synaptic Transmission / Fluorescent Antibody Technique / Rats / Myasthenia Gravis / Human Disease / Action Potentials / Individual Difference / Neuromuscular Junction / Radioimmunoassay

Differential expression of Vibrio vulnificus capsular polysaccharide

Genetics / Electron Microscopy / Flow Cytometry / Gene expression / Biological Sciences / Infection and immunity / Virulence / Humans / Mutation / Mice / United States / Animals / Infection / Monoclonal Antibodies / Animal Model / Vibrio / Environmental Conditions / Monoclonal Antibody / Rabbits / Human Disease / Liver Disease / Cell Surface Markers / Enzyme Linked Immunosorbent Assay / Differential expression / Infection and immunity / Virulence / Humans / Mutation / Mice / United States / Animals / Infection / Monoclonal Antibodies / Animal Model / Vibrio / Environmental Conditions / Monoclonal Antibody / Rabbits / Human Disease / Liver Disease / Cell Surface Markers / Enzyme Linked Immunosorbent Assay / Differential expression

Functional characterization of a novel Toxoplasma gondii glycosyltransferase: UDP-N-acetyl-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T3

Molecular Biology / Drosophila melanogaster / Toxoplasma / Toxoplasma gondii / Animals / Enzyme / Molecular cloning / Protein Sequence Analysis / Amino Acid Sequence / Human Disease / In Silico / Membrane Protein / Reverse Transcriptase / Recombinant Proteins / Nucleotides / Biochemistry and cell biology / Molecular Sequence Data / Enzyme / Molecular cloning / Protein Sequence Analysis / Amino Acid Sequence / Human Disease / In Silico / Membrane Protein / Reverse Transcriptase / Recombinant Proteins / Nucleotides / Biochemistry and cell biology / Molecular Sequence Data

Deficient p75 low-affinity neurotrophin receptor expression exacerbates experimental allergic encephalomyelitis in C57/BL6 mice

Immunology / Electron Microscopy / Multiple sclerosis / Immunohistochemistry / Gene expression / Neuroimmunology / Probability / Endothelial Cells / Mice / Blood brain barrier / Animals / Immunization / Central Nervous System / Glycoproteins / Endothelial cell / Time Factors / Blood Vessels / Human Disease / Experimental Autoimmune Encephalomyelitis / Knockout Mice / Neurosciences / Neuroimmunology / Probability / Endothelial Cells / Mice / Blood brain barrier / Animals / Immunization / Central Nervous System / Glycoproteins / Endothelial cell / Time Factors / Blood Vessels / Human Disease / Experimental Autoimmune Encephalomyelitis / Knockout Mice / Neurosciences

Generalized CNS disease and massive GM1-ganglioside accumulation in mice defective in lysosomal acid β-galactosidase

Genetics / Biological Sciences / Brain / Humans / Mice / Animals / Spinal Cord / Embryonic Stem Cell / Human Molecular Genetics / Mouse Model / Homologous Recombination / Human Disease / Glycosphingolipids / Gangliosides / Animals / Spinal Cord / Embryonic Stem Cell / Human Molecular Genetics / Mouse Model / Homologous Recombination / Human Disease / Glycosphingolipids / Gangliosides

A new preclinical femoral head osteonecrosis model in sheep

Magnetic Resonance Imaging / Sheep / Animals / Animal Model / Clinical Sciences / Gold Standard / Biological treatment / Disease Progression / Human Disease / Freezing / Gold Standard / Biological treatment / Disease Progression / Human Disease / Freezing

A diet-induced mouse model for glutaric aciduria type I

Magnetic Resonance Imaging / Diet / Survival Analysis / Brain / Mice / Blood brain barrier / Female / Animals / Plant tissue Culture Techniques / Male / Astrocyte / Animal Model / Neurons / Mouse Model / Lysine / Subarachnoid haemorrhage / Human Disease / Dietary Protein / High-protein Diet / Autosomal Recessive / White Matter Lesions / Corpus striatum / Blood brain barrier / Female / Animals / Plant tissue Culture Techniques / Male / Astrocyte / Animal Model / Neurons / Mouse Model / Lysine / Subarachnoid haemorrhage / Human Disease / Dietary Protein / High-protein Diet / Autosomal Recessive / White Matter Lesions / Corpus striatum

Human xeroderma pigmentosum group D gene encodes a DMA helicase

Genetics / DNA repair / Transcription Factors / Multidisciplinary / Nature / Saccharomyces cerevisiae / Humans / Cell fusion / Skin Cancer / Escherichia coli / Ultraviolet / Nucleotide Excision Repair / Proteins / Molecular cloning / Human Disease / Recombinant Proteins / DNA binding proteins / Xeroderma Pigmentosum / Adenosine Triphosphate / Saccharomyces cerevisiae / Humans / Cell fusion / Skin Cancer / Escherichia coli / Ultraviolet / Nucleotide Excision Repair / Proteins / Molecular cloning / Human Disease / Recombinant Proteins / DNA binding proteins / Xeroderma Pigmentosum / Adenosine Triphosphate

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