HeLa cells

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

British / Apoptosis / Caspases / Humans / Liver / Mice / Female / Animals / Male / Brain Ischemia / Caspase / Doxorubicin / Rats / Myocardial Infarction / HeLa cells / Tumor necrosis factor-alpha / Cysteine Proteinase Inhibitors / DNA fragmentation / Cycloheximide / Mice / Female / Animals / Male / Brain Ischemia / Caspase / Doxorubicin / Rats / Myocardial Infarction / HeLa cells / Tumor necrosis factor-alpha / Cysteine Proteinase Inhibitors / DNA fragmentation / Cycloheximide

MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

Kinetics / Cellular Reprogramming / Multidisciplinary / Nature / Cell line / Cell Differentiation / Humans / Mice / Animals / Alternative splicing / Embryonic Stem Cells / RNA-binding proteins / HeLa cells / Alternative Splicing / Induced Pluripotent Stem Cells / Human Fibroblasts / DNA binding proteins / Cell Differentiation / Humans / Mice / Animals / Alternative splicing / Embryonic Stem Cells / RNA-binding proteins / HeLa cells / Alternative Splicing / Induced Pluripotent Stem Cells / Human Fibroblasts / DNA binding proteins

Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides

RNA interference / Humans / Cell Death / Peptides / Clinical Sciences / microRNAs / Cell nucleus / HeLa cells / Molecular weight / Oxidation-Reduction / microRNAs / Cell nucleus / HeLa cells / Molecular weight / Oxidation-Reduction

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

Multidisciplinary / Nature / Cell line / Humans / Mice / Animals / Cell Death / HeLa cells / Genetic Recombination / Telomere / Base Sequence / Animals / Cell Death / HeLa cells / Genetic Recombination / Telomere / Base Sequence

A Nucleolus-Predominant piggyBac Transposase, NP-mPB, Mediates Elevated Transposition Efficiency in Mammalian Cells

Multidisciplinary / HIV / Mammals / Humans / Mice / Animals / C2H2 zinc fingers / Genome / PLoS one / HeLa cells / Codon / Animals / C2H2 zinc fingers / Genome / PLoS one / HeLa cells / Codon

Phosphatidic Acid Induces Ligand-independent Epidermal Growth Factor Receptor Endocytic Traffic through PDE4 Activation

Molecular Biology / Flow Cytometry / Signal Transduction / Biological Sciences / RNA interference / Humans / Mice / Endocytosis / cyclic AMP / Animals / Epidermal Growth Factor Receptor / HeLa cells / Phospholipase D / Propranolol / Hydrolysis / Endosomes / Phosphatidic acid / Clathrin / Immunoblotting / Humans / Mice / Endocytosis / cyclic AMP / Animals / Epidermal Growth Factor Receptor / HeLa cells / Phospholipase D / Propranolol / Hydrolysis / Endosomes / Phosphatidic acid / Clathrin / Immunoblotting

A Novel Cell-Penetrating Peptide Sequence Derived by Structural Minimization of a Snake Toxin Exhibits Preferential Nucleolar Localization

Organic Chemistry / Medicinal Chemistry / Snake venoms / Humans / Animals / HeLa cells / Medicinal / Amino Acid Sequence / Protein Transport / HeLa cells / Medicinal / Amino Acid Sequence / Protein Transport

Computer-based fluorescence quantification: a novel approach to study nucleolar biology

RNA / Kinetics / Fluorescence Microscopy / Cell Cycle / Image Analysis / Humans / High throughput screening / Stress response / Single Cell / HeLa cells / Very high throughput / Biological Process / Large Data Sets / Biochemistry and cell biology / Image Acquisition / Automatic data processing / Humans / High throughput screening / Stress response / Single Cell / HeLa cells / Very high throughput / Biological Process / Large Data Sets / Biochemistry and cell biology / Image Acquisition / Automatic data processing

Cyclic AMP Produced inside Mitochondria Regulates Oxidative Phosphorylation

Carbon Dioxide / Mitochondria / Signal Transduction / Humans / Reactive Oxygen Species / Mice / cyclic AMP / Animals / HeLa cells / Oxidative phosphorylation / Oxidation-Reduction / Biochemistry and cell biology / Mice / cyclic AMP / Animals / HeLa cells / Oxidative phosphorylation / Oxidation-Reduction / Biochemistry and cell biology

Loss of Protein Kinase PKR Expression in Human HeLa Cells Complements the Vaccinia Virus E3L Deletion Mutant Phenotype by Restoration of Viral Protein Synthesis

Virology / Apoptosis / Gene Silencing / Protein synthesis / Biological Sciences / RNA interference / Humans / Mutation / Virus / Phosphorylation / Phenotype / RNA-binding proteins / HeLa cells / Vaccinia Virus / Complement / Protein Kinase / double-stranded RNA / RNA interference / Humans / Mutation / Virus / Phosphorylation / Phenotype / RNA-binding proteins / HeLa cells / Vaccinia Virus / Complement / Protein Kinase / double-stranded RNA

Identification of potential protein dithiol-disulfide substrates of mammalian Grx2

Protein Folding / Cytoskeleton / Mammals / Biological Sciences / Humans / Mice / Animals / Physical sciences / Proteins / Cell nucleus / HeLa cells / Protein isoforms / Toluene / Oxidation-Reduction / Biochemistry and cell biology / Mice / Animals / Physical sciences / Proteins / Cell nucleus / HeLa cells / Protein isoforms / Toluene / Oxidation-Reduction / Biochemistry and cell biology

Characterisation of an Endogenous Protein Kinase Activity in Ribonucleoprotein Structures Containing Heterogenous Nuclear RNA in HeLa Cell Nuclei

Kinetics / Protein Kinases / Amino Acids / Cell nucleus / HeLa cells / Molecular weight / Protein Kinase / Ribonucleoproteins / Cations / Biochemistry and cell biology / Molecular weight / Protein Kinase / Ribonucleoproteins / Cations / Biochemistry and cell biology

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

Multidisciplinary / Humans / Cell fusion / Mice / Cholesterol / Animals / Drug Delivery Systems / Lipid Raft / Shell Half-Life / Viral Infection / HeLa cells / Heptad Repeat / Lipid Rafts / Mechanism of action / Antiviral Activity / Structure activity Relationship / Animals / Drug Delivery Systems / Lipid Raft / Shell Half-Life / Viral Infection / HeLa cells / Heptad Repeat / Lipid Rafts / Mechanism of action / Antiviral Activity / Structure activity Relationship

Hydrogen peroxide induces apoptosis in HeLa cells through mitochondrial pathway

Genetics / Mitochondria / DNA damage / Apoptosis / Humans / Reactive Oxygen Species / Cytochrome C / Cervical Cancer / Caspase / Hydrogen Peroxide / HeLa cells / DNA binding proteins / Reactive Oxygen Species / Cytochrome C / Cervical Cancer / Caspase / Hydrogen Peroxide / HeLa cells / DNA binding proteins

In vitro cytotoxicity, in vivo biodistribution and antitumor activity of HPMA copolymer–5-fluorouracil conjugates

Pharmaceutical Chemistry / Cell line / Humans / Mice / Female / Animals / European / Spectrum / Time Factors / HeLa cells / Antitumor Activity / Drug Carriers / Drug Compounding / Drug Stability / Biological Availability / Cell Survival / Tumor Growth / Clinical Application / Control Group / Animals / European / Spectrum / Time Factors / HeLa cells / Antitumor Activity / Drug Carriers / Drug Compounding / Drug Stability / Biological Availability / Cell Survival / Tumor Growth / Clinical Application / Control Group

CDK13, a New Potential Human Immunodeficiency Virus Type 1 Inhibitory Factor Regulating Viral mRNA Splicing

Virology / Gene expression / HIV / Biological Sciences / Humans / Chromatin remodeling / Immunoprecipitation / Enzyme / Human immunodeficiency virus / HeLa cells / Protein Binding / Chromatin remodeling / Immunoprecipitation / Enzyme / Human immunodeficiency virus / HeLa cells / Protein Binding
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