Drug Discovery - Page 2

ChemInform Abstract: Unusual Antimalarial Meroditerpenes from Tropical Red Macroalgae

Organic Chemistry / Drug Discovery / Pharmacognosy / Structural Analysis / In Vitro / Humans / Circular Dichroism / Natural Product / Seaweed / Isolation / Absolute Configuration / Diterpenes / Plasmodium falciparum / Antimalarials / Conformational Analysis / Biological activity / Terpenoid / Humans / Circular Dichroism / Natural Product / Seaweed / Isolation / Absolute Configuration / Diterpenes / Plasmodium falciparum / Antimalarials / Conformational Analysis / Biological activity / Terpenoid

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Unusual antimalarial meroditerpenes from tropical red macroalgae

Organic Chemistry / Drug Discovery / Pharmacognosy / Structural Analysis / In Vitro / Humans / Circular Dichroism / Natural Product / Seaweed / Isolation / Absolute Configuration / Diterpenes / Plasmodium falciparum / Antimalarials / Conformational Analysis / Biological activity / Terpenoid / Humans / Circular Dichroism / Natural Product / Seaweed / Isolation / Absolute Configuration / Diterpenes / Plasmodium falciparum / Antimalarials / Conformational Analysis / Biological activity / Terpenoid

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A photosynthetic alveolate closely related to apicomplexan parasites

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Photosynthesis / Biotechnology / Systems Biology / Cancer / Taxonomy / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / Biological Sciences / DNA / Phylogeny / Chlorophyll / Animals / Parasites / Cell Signalling / Medical Research / Ultrastructure / Cell nucleus / Plasmodium falciparum / Codon / Eukaryotic Cells / Power Modeling / Earth Science / Chlorophyll a / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Photosynthesis / Biotechnology / Systems Biology / Cancer / Taxonomy / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / Biological Sciences / DNA / Phylogeny / Chlorophyll / Animals / Parasites / Cell Signalling / Medical Research / Ultrastructure / Cell nucleus / Plasmodium falciparum / Codon / Eukaryotic Cells / Power Modeling / Earth Science / Chlorophyll a

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Larvicidal activity of metabolites from the endophytic Podospora sp. against the malaria vector Anopheles gambiae

Microbiology / Parasitology / Medical Microbiology / Drug Discovery / Magnetic Resonance Spectroscopy / Insecticides / X Rays / Parasite / Animals / Natural Product / Anopheles gambiae / VECTOR / Activity / Anthraquinones / Larva / Veterinary Sciences / Lethal Dose / Insect Vectors / Sterigmatocystin / Insecticides / X Rays / Parasite / Animals / Natural Product / Anopheles gambiae / VECTOR / Activity / Anthraquinones / Larva / Veterinary Sciences / Lethal Dose / Insect Vectors / Sterigmatocystin

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Photonics: Transparency on an optical chip

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Optical Communication / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Information Processing / Signal Transduction / Astronomy / DNA / Cell Signalling / Medical Research / Chip / Earth Science / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Optical Communication / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Information Processing / Signal Transduction / Astronomy / DNA / Cell Signalling / Medical Research / Chip / Earth Science

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Self-assembly of amphiphilic dendritic dipeptides into helical pores

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Electron Microscopy / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Self Assembly / Nanotechnology / Magnetic Resonance Spectroscopy / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Molecular Recognition / Porosity / Circular Dichroism / Differential scanning calorimetry / Biopolymers / Cell Signalling / Medical Research / Protein structure / Protein Function / Antibacterial activity / Hydrogen Bonding / Protein Quaternary Structure / Membrane Filtration / Protons / Earth Science / Functional Properties / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Electron Microscopy / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Self Assembly / Nanotechnology / Magnetic Resonance Spectroscopy / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Molecular Recognition / Porosity / Circular Dichroism / Differential scanning calorimetry / Biopolymers / Cell Signalling / Medical Research / Protein structure / Protein Function / Antibacterial activity / Hydrogen Bonding / Protein Quaternary Structure / Membrane Filtration / Protons / Earth Science / Functional Properties

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Doushantuo embryos preserved inside diapause egg cysts

Ancient History / Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Stratigraphy / Developmental Biology / Immunology / Climate Change / Microstructure / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / China / Nanotechnology / Interpretation / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Phylogeny / Far East / Proterozoic / Precambrian / Microfossils / Fossils / Animals / Bacteria / Cell Signalling / Medical Research / Paleozoic / South China / Chine / Time Factors / Microstructures / Reproducibility of Results / Glaciation / Carbonate Rocks / Eukaryotic Cells / Sedimentary Rocks / Embryos / Earth Science / Blastula / Acritarchs / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Stratigraphy / Developmental Biology / Immunology / Climate Change / Microstructure / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / China / Nanotechnology / Interpretation / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Phylogeny / Far East / Proterozoic / Precambrian / Microfossils / Fossils / Animals / Bacteria / Cell Signalling / Medical Research / Paleozoic / South China / Chine / Time Factors / Microstructures / Reproducibility of Results / Glaciation / Carbonate Rocks / Eukaryotic Cells / Sedimentary Rocks / Embryos / Earth Science / Blastula / Acritarchs

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Huperzine A from Huperzia species--an ethnopharmacolgical review

Complementary and Alternative Medicine / Clinical Trial / Plant Biology / Drug Discovery / China / Ethnopharmacology / Medicinal Plants / Traditional Chinese Medicine / Humans / Europe / Alkaloids / Cholinesterase inhibitors / Sesquiterpenes / Myasthenia Gravis / Natural Resource / Huperzia / Alzheimer Disease / Ethnopharmacology / Medicinal Plants / Traditional Chinese Medicine / Humans / Europe / Alkaloids / Cholinesterase inhibitors / Sesquiterpenes / Myasthenia Gravis / Natural Resource / Huperzia / Alzheimer Disease

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Experimental and computational approaches to electrical conductor loading characteristics

Pharmacology / Thermodynamics / Physical Chemistry / Polymorphism / Protein Folding / Drug Discovery / Drug delivery / Rule of Law / Adsorption / Protein Design / Computers / Permeability / High throughput screening / Advanced Drug Delivery Research / Gene Network / Solubility / Free Energy / Protein Function / Biological Network / Biological systems / Molecular weight / Rule Based / Pharmaceutical preparations / Drug Discovery / Drug delivery / Rule of Law / Adsorption / Protein Design / Computers / Permeability / High throughput screening / Advanced Drug Delivery Research / Gene Network / Solubility / Free Energy / Protein Function / Biological Network / Biological systems / Molecular weight / Rule Based / Pharmaceutical preparations

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Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase

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Corrigendum: EphB receptor activity suppresses colorectal cancer progression

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Colorectal cancer / Signal Transduction / Astronomy / DNA / Cell Signalling / Medical Research / Earth Science / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Colorectal cancer / Signal Transduction / Astronomy / DNA / Cell Signalling / Medical Research / Earth Science

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EphB receptor activity suppresses colorectal cancer progression

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Colorectal cancer / Signal Transduction / Astronomy / DNA / Humans / Mutation / Mice / Animals / Cell Signalling / Medical Research / Disease Progression / Adenoma / Earth Science / Down-Regulation / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Colorectal cancer / Signal Transduction / Astronomy / DNA / Humans / Mutation / Mice / Animals / Cell Signalling / Medical Research / Disease Progression / Adenoma / Earth Science / Down-Regulation

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Anti-tumor agents 255: Novel glycyrrhetinic acid–dehydrozingerone conjugates as cytotoxic agents

Organic Chemistry / Drug Discovery / Humans / Ursolic Acid / Cytotoxic Activity / Neoplasms / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antineoplastic Agents / Cytotoxins / Molecular Structure / Neoplasms / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antineoplastic Agents / Cytotoxins / Molecular Structure

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Planetary science: Inside Enceladus

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Exobiology / Astronomy / DNA / Cell Signalling / Medical Research / Chemical Analysis / Ice / South Pole / Saturn / Earth Science / Organic Chemicals / Hot Temperature / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Exobiology / Astronomy / DNA / Cell Signalling / Medical Research / Chemical Analysis / Ice / South Pole / Saturn / Earth Science / Organic Chemicals / Hot Temperature

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A practical guide to Bayesian group sequential designs

Statistics / Research Design / Drug Discovery / Humans / Bayes Theorem / Pharmaceutical Statistics / Crohn Disease / Pharmaceutical Statistics / Crohn Disease

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Classifying Molecules Using a Sparse Probabilistic Kernel Binary Classifier

Algorithms / Computational Biology / Drug Discovery / Enzyme Inhibitors / THEORETICAL AND COMPUTATIONAL CHEMISTRY

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