Biological Availability - Page 2

Enantiospecific ketoprofen concentrations in plasma after oral and intramuscular administration in growing pigs

Animal Production / Female / Animals / Male / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Shell Half-Life / Swine / Veterinary Sciences / Biological Availability / Cross-Over Studies / Area Under Curve / High Performance Liquid Chromatography / Shell Half-Life / Swine / Veterinary Sciences / Biological Availability / Cross-Over Studies / Area Under Curve

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Enantiospecific ketoprofen concentrations in plasma after oral and intramuscular administration in growing pigs

Animal Production / Female / Animals / Male / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Shell Half-Life / Swine / Veterinary Sciences / Biological Availability / Cross-Over Studies / Area Under Curve / High Performance Liquid Chromatography / Shell Half-Life / Swine / Veterinary Sciences / Biological Availability / Cross-Over Studies / Area Under Curve

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Intranasal midazolam: a comparison of two delivery devices in human volunteers

Pharmacy / Adolescent / Humans / Pharmacology and Clinical pharmacy / Female / Male / Middle Aged / Adult / Intranasal Administration / Biological Availability / Cross-Over Studies / Area Under Curve / Midazolam / Male / Middle Aged / Adult / Intranasal Administration / Biological Availability / Cross-Over Studies / Area Under Curve / Midazolam

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Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

Organic Chemistry / Humans / Propionic Acid / Alanine / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Structure activity Relationship / Protein Binding / Biological Availability

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Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation

Pharmaceutical Technology / Polysaccharides / Pharmaceutical Chemistry / Humans / Wettability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability

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A semiparametric deconvolution model to establish in vivo-in vitro correlation applied to OROS oxybutynin

Modeling / Prediction / Pharmacokinetics / Pharmaceutical Chemistry / Dosage Form / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer

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Preliminary pharmaceutical development of antimalarial–antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas

Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability

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Discovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a Diaryltetrahydronaphthalene

Organic Chemistry / Medicinal Chemistry / Cell Division / Estrogen Receptor / Humans / Cholesterol / Female / Animals / Bone Density / Rats / Medicinal / Uterus / Biological Availability / #Hypolipidemic Agents / Ovariectomy / Cholesterol / Female / Animals / Bone Density / Rats / Medicinal / Uterus / Biological Availability / #Hypolipidemic Agents / Ovariectomy

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Effect of PF-04217329 a prodrug of a selective prostaglandin EP2 agonist on intraocular pressure in preclinical models of glaucoma

Pharmacology / Quantum Physics / Calcium / Pharmacokinetics / Cornea / Dogs / Prodrugs / Humans / cyclic AMP / Glaucoma / Animals / Male / Intraocular Pressure / Optometry and Ophthalmology / Topical Drug Administration / Clinical Study / Macaca fascicularis / Iris / Rabbits / Visual Field / Biological Availability / Ophthalmic Solutions / Neurosciences / Prostaglandin E2 / Primary Open Angle Glaucoma / Dogs / Prodrugs / Humans / cyclic AMP / Glaucoma / Animals / Male / Intraocular Pressure / Optometry and Ophthalmology / Topical Drug Administration / Clinical Study / Macaca fascicularis / Iris / Rabbits / Visual Field / Biological Availability / Ophthalmic Solutions / Neurosciences / Prostaglandin E2 / Primary Open Angle Glaucoma

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In vitro cytotoxicity, in vivo biodistribution and antitumor activity of HPMA copolymer–5-fluorouracil conjugates

Pharmaceutical Chemistry / Cell line / Humans / Mice / Female / Animals / European / Spectrum / Time Factors / HeLa cells / Antitumor Activity / Drug Carriers / Drug Compounding / Drug Stability / Biological Availability / Cell Survival / Tumor Growth / Clinical Application / Control Group / Animals / European / Spectrum / Time Factors / HeLa cells / Antitumor Activity / Drug Carriers / Drug Compounding / Drug Stability / Biological Availability / Cell Survival / Tumor Growth / Clinical Application / Control Group

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Vancomycin pharmacokinetics in neonates receiving extracorporeal membrane oxygenation

Vancomycin / Humans / Pharmacotherapy / Newborn Infant / Shell Half-Life / Anti-Bacterial Agents / Retrospective Studies / Bacterial infections / Biological Availability / Extracorporeal Membrane Oxygenation / Anti-Bacterial Agents / Retrospective Studies / Bacterial infections / Biological Availability / Extracorporeal Membrane Oxygenation

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Intranasal midazolam: a comparison of two delivery devices in human volunteers

Pharmacy / Adolescent / Humans / Pharmacology and Clinical pharmacy / Female / Male / Middle Aged / Adult / Intranasal Administration / Biological Availability / Cross-Over Studies / Area Under Curve / Midazolam / Male / Middle Aged / Adult / Intranasal Administration / Biological Availability / Cross-Over Studies / Area Under Curve / Midazolam

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5\'-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters

Pharmacokinetics / Drug metabolism / Magnetic Resonance Spectroscopy / Dogs / Cell line / Female / Animals / Male / Biotransformation / Rabbits / Biological Availability / Delayed-Action Preparations / Intracellular / Female / Animals / Male / Biotransformation / Rabbits / Biological Availability / Delayed-Action Preparations / Intracellular

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Coadministration of Gatifloxacin and Multivitamin Preparation Containing Minerals: Potential Treatment Failure in an Elderly Patient

Vitamins / Minerals / Drug interactions / Humans / Female / Metals / Aged / Anti-Bacterial Agents / Biological Availability / Fluoroquinolones / Metals / Aged / Anti-Bacterial Agents / Biological Availability / Fluoroquinolones

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A non-parametric confidence interval method

Kinetics / Bayesian Analysis / Biological Availability / Confidence Interval / Statistics as Topic

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Ethyl (3 S ,4a R ,6 S ,8a R )-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester: A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Models of Acute Migraine

Organic Chemistry / Medicinal Chemistry / Calcium / Cell line / Prodrugs / Humans / Animals / Animal Model / Rats / Radioligand Assay / Medicinal / Wistar Rats / Carboxylic Acids / Esters / Biological Availability / Acute Disease / Humans / Animals / Animal Model / Rats / Radioligand Assay / Medicinal / Wistar Rats / Carboxylic Acids / Esters / Biological Availability / Acute Disease

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