Binding Site

Study of a sterol esterase secreted by Ophiostoma piceae: Sequence, model and biochemical properties

Biological Sciences / Crystal structure / Physical sciences / Pichia pastoris / Enzyme / Molecular cloning / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / Binding Site / Molecular cloning / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / Binding Site

Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR

Immune response / Animal Studies / Magnetic Resonance Spectroscopy / Biological Sciences / Molecular / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1 / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1

Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-119 mapped by TROSY NMR

Immune response / Animal Studies / Magnetic Resonance Spectroscopy / Biological Sciences / Molecular / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1 / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1

Sequential Logic Model Deciphers Dynamic Transcriptional Control of Gene Expressions

Gene regulation / Transcription Regulation / Morphogenesis / Gene expression / Multidisciplinary / Network Dynamics / Cell Differentiation / Mutagenesis / Animals / Ligand Binding / Gene Regulatory Networks / Transcription Factor / PLoS one / Sea Urchins / mRna expression levels / Sea Urchin / Binding Site / Gene Expression Regulation / Cell Adhesion Molecules / Switching Activity / Finite State Machine / Network Dynamics / Cell Differentiation / Mutagenesis / Animals / Ligand Binding / Gene Regulatory Networks / Transcription Factor / PLoS one / Sea Urchins / mRna expression levels / Sea Urchin / Binding Site / Gene Expression Regulation / Cell Adhesion Molecules / Switching Activity / Finite State Machine

An antiviral disulfide compound blocks interaction between arenavirus Z protein and cellular promyelocytic leukemia protein

Transcription Factors / Cell line / Humans / Zinc / Zinc Finger / Guanidines / Virus infection / Binding Site / Antiviral Agents / Biochemistry and cell biology / Guanidines / Virus infection / Binding Site / Antiviral Agents / Biochemistry and cell biology

Allosteric  1-Adrenoreceptor Antagonism by the Conopeptide  -TIA

Kinetics / Fluorescence Microscopy / Biological Chemistry / Biological Sciences / Smooth muscle / Animals / Male / Peptides / CHEMICAL SCIENCES / Rats / Time Factors / Arginine / Wistar Rats / Protein Conformation / Alanine / Amino Acid Sequence / Structure activity Relationship / Protein Binding / Binding Site / Full Length Movies / Animals / Male / Peptides / CHEMICAL SCIENCES / Rats / Time Factors / Arginine / Wistar Rats / Protein Conformation / Alanine / Amino Acid Sequence / Structure activity Relationship / Protein Binding / Binding Site / Full Length Movies

PAX3/Forkhead Homolog in Rhabdomyosarcoma Oncoprotein Activates Glucose Transporter 4 Gene Expression in Vivo and in Vitro

Transcription Factors / Gene expression / Cell line / Humans / Glucose / Mice / Animals / Clinical / Muscles / Clinical Sciences / Glucose Transport / Transfection / Glucose Uptake / DNA binding proteins / Binding Site / Tissue Specificity / Mice / Animals / Clinical / Muscles / Clinical Sciences / Glucose Transport / Transfection / Glucose Uptake / DNA binding proteins / Binding Site / Tissue Specificity

Engineering of Pyridine Nucleotide Specificity of Nitrate Reductase: Mutagenesis of Recombinant CytochromebReductase Fragment ofNeurospora crassaNADPH:Nitrate Reductase

Kinetics / Protein Engineering / Neurospora crassa / Escherichia coli / Nitrate Reductase / Enzyme / Steady state / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Recombinant Proteins / Site-directed Mutagenesis / Binding Site / Nucleotides / Biochemistry and cell biology / Molecular Sequence Data / Enzyme / Steady state / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Recombinant Proteins / Site-directed Mutagenesis / Binding Site / Nucleotides / Biochemistry and cell biology / Molecular Sequence Data

Crystal structure of staphylococcal enterotoxin B, a superantigen

Multidisciplinary / Nature / T cell receptor / Crystal structure / Enterotoxins / Animals / Staphylococcus aureus / Protein Secondary Structure Prediction / X ray diffraction / Protein Conformation / Biological activity / Binding Site / STAPHYLOCOCCAL-ENTEROTOXIN-B / Animals / Staphylococcus aureus / Protein Secondary Structure Prediction / X ray diffraction / Protein Conformation / Biological activity / Binding Site / STAPHYLOCOCCAL-ENTEROTOXIN-B

Bioactive angiotensin peptides

Humans / Hypertension / Blood Pressure / Renin Angiotensin Aldosterone System / Animals / Peptides / Clinical Sciences / Sensitivity and Specificity / Angiotensin II / Binding Site / Peptides / Clinical Sciences / Sensitivity and Specificity / Angiotensin II / Binding Site

Probing RNA-protein interactions using pyrene-labeled oligodeoxynucleotides: Qβ replicase efficiently binds small RNAs by recognizing pyrimidine residues

Molecular Biology / RNA / Fluorescent Dyes and Reagents / Fluorescence Lifetime / Proteins / Small RNA / Real Time / Steady state / Fluorescence anisotropy / Base Sequence / RNA Dependent RNA Polymerase / Fluorometry / Binding Site / Nucleic Acid Conformation / Dissociation Constant / DNA probes / Biochemistry and cell biology / Molecular Structure / Nucleic Acid / Titrimetry / single stranded DNA / Binding affinity / Molecular Sequence Data / Small RNA / Real Time / Steady state / Fluorescence anisotropy / Base Sequence / RNA Dependent RNA Polymerase / Fluorometry / Binding Site / Nucleic Acid Conformation / Dissociation Constant / DNA probes / Biochemistry and cell biology / Molecular Structure / Nucleic Acid / Titrimetry / single stranded DNA / Binding affinity / Molecular Sequence Data

A novel serotonin transporter ligand: (5-Iodo-2-(2-dimethylaminomethylphenoxy)-benzyl alcohol

Brain Imaging / Metabolism / Positron Emission Tomography / DISTRIBUTION / Serotonin / Dopamine / Brain / Iodine / Animals / Serotonin Transporter / Male / Central Nervous System / Rat Brain / Membrane transport proteins / Clinical Sciences / Hydrogen Peroxide / Rats / Single Photon Emission Computed Tomography / Rat / Swine / Positron / Distribution / Radiopharmaceuticals / Chemical Synthesis / Ligands / Binding Site / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Binding affinity / Dopamine / Brain / Iodine / Animals / Serotonin Transporter / Male / Central Nervous System / Rat Brain / Membrane transport proteins / Clinical Sciences / Hydrogen Peroxide / Rats / Single Photon Emission Computed Tomography / Rat / Swine / Positron / Distribution / Radiopharmaceuticals / Chemical Synthesis / Ligands / Binding Site / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Binding affinity

Common Promoter Elements in Odorant and Vomeronasal Receptor Genes

Gene regulation / Gene expression / Multidisciplinary / Odorant Receptor / Mice / Animals / Vomeronasal Organ / Sensory Neuron / Comparative Analysis / Neurons / PLoS one / Amino Acid Sequence / Binding Site / Molecular Sequence Data / Animals / Vomeronasal Organ / Sensory Neuron / Comparative Analysis / Neurons / PLoS one / Amino Acid Sequence / Binding Site / Molecular Sequence Data

Nitric oxide, a biological effector

Nitric oxide / Cell Signalling / Nitrogen / Electron Paramagnetic Resonance Spectroscopy / Superoxide Anion / Binding Site / Electron Paramagnetic Resonance / Guanylate Cyclase / Binding Site / Electron Paramagnetic Resonance / Guanylate Cyclase

Transcription Factor Decoy Molecules Based on a Peptide Nucleic Acid (PNA)-DNA Chimera Mimicking Sp1 Binding Sites

Biological Chemistry / Transcription Factors / Biological Sciences / Humans / Peptide Nucleic Acids / Biological / Liposomes / Transcription Factor / CHEMICAL SCIENCES / Cell nucleus / Time Factors / Transfection / Protein Binding / Binding Site / Oligonucleotides / Biological / Liposomes / Transcription Factor / CHEMICAL SCIENCES / Cell nucleus / Time Factors / Transfection / Protein Binding / Binding Site / Oligonucleotides

Sequential Logic Model Deciphers Dynamic Transcriptional Control of Gene Expressions

Gene regulation / Transcription Regulation / Morphogenesis / Gene expression / Multidisciplinary / Network Dynamics / Cell Differentiation / Mutagenesis / Animals / Ligand Binding / Gene Regulatory Networks / Transcription Factor / PLoS one / Sea Urchins / mRna expression levels / Sea Urchin / Binding Site / Gene Expression Regulation / Cell Adhesion Molecules / Switching Activity / Finite State Machine / Network Dynamics / Cell Differentiation / Mutagenesis / Animals / Ligand Binding / Gene Regulatory Networks / Transcription Factor / PLoS one / Sea Urchins / mRna expression levels / Sea Urchin / Binding Site / Gene Expression Regulation / Cell Adhesion Molecules / Switching Activity / Finite State Machine
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