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Nucleic acid polymerases use a general acid for nucleotidyl transfer
Biochemistry / Genetics / Biophysics / Molecular Biology / RNA / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid
Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases
Multidisciplinary / Sequence alignment / Protein Kinases / Mutation / Amino Acids / Active site / Substrate Specificity / Protein Kinase / S100 protein family / Eukaryotic Cells / Amino Acid Sequence / Static Electricity / Active site / Substrate Specificity / Protein Kinase / S100 protein family / Eukaryotic Cells / Amino Acid Sequence / Static Electricity
Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases
Multidisciplinary / Sequence alignment / Protein Kinases / Mutation / Amino Acids / Active site / Substrate Specificity / Protein Kinase / S100 protein family / Eukaryotic Cells / Amino Acid Sequence / Static Electricity / Active site / Substrate Specificity / Protein Kinase / S100 protein family / Eukaryotic Cells / Amino Acid Sequence / Static Electricity
Inactivation of porcine kidney betaine aldehyde dehydrogenase by hydrogen peroxide
Kinetics / Mass Spectrometry / Molecular modeling / Kidney / Reactive Oxygen Species / Stress response / Animals / Chemico-biological Interactions / Enzyme / Hydrogen Peroxide / Active site / Swine / Enzyme activity / Amino Acid Profile / Protein Conformation / Gb / Glycine Betaine / Ligands / Binding Site / Aldehyde Dehydrogenase / Biochemistry and cell biology / Betaine Aldehyde Dehydrogenase / Disulfide bond / Stress response / Animals / Chemico-biological Interactions / Enzyme / Hydrogen Peroxide / Active site / Swine / Enzyme activity / Amino Acid Profile / Protein Conformation / Gb / Glycine Betaine / Ligands / Binding Site / Aldehyde Dehydrogenase / Biochemistry and cell biology / Betaine Aldehyde Dehydrogenase / Disulfide bond
Engineering the Exo-loop of Trichoderma reesei Cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D
Molecular Biology / Protein Engineering / Macromolecular X-Ray Crystallography / Molecular / Sequence alignment / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology
Detection of NADPH-diaphorase activity in Paramecium primaurelia
Microbiology / Medical Microbiology / Immunohistochemistry / Enzyme Inhibitors / Animals / Acetylcholine / Rat Brain / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Enzyme / European / Active site / Nitric Oxide Synthase / Substrate Specificity / Molecular Mass / NAD / Hydrogen-Ion Concentration / Paramecium / Cell Cell Interaction / Immunoblotting / Acetylcholine / Rat Brain / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Enzyme / European / Active site / Nitric Oxide Synthase / Substrate Specificity / Molecular Mass / NAD / Hydrogen-Ion Concentration / Paramecium / Cell Cell Interaction / Immunoblotting
Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA
Catalysis / DNA / Humans / Escherichia coli / Animals / Nucleic acid hybridization / Intestines / Molecular cloning / Active site / Swine / Codon / Rabbits / Amino Acid Sequence / Base Sequence / Protein Biosynthesis / Biochemistry and cell biology / Nucleic acid hybridization / Intestines / Molecular cloning / Active site / Swine / Codon / Rabbits / Amino Acid Sequence / Base Sequence / Protein Biosynthesis / Biochemistry and cell biology
Ser72Pro active-site disease mutation in human lysosomal aspartylglucosaminidase: abnormal intracellular processing and evidence for extracellular activation
Biological Sciences / Cercopithecus aethiops / Humans / Animals / Human Molecular Genetics / Endoplasmic Reticulum / Proline / Enzyme / Active site / Enzyme activity / Amino Acid Profile / Lysosomes / Lysosomal Storage Diseases / Transient Expression / Proteolytic activity / Endoplasmic Reticulum / Proline / Enzyme / Active site / Enzyme activity / Amino Acid Profile / Lysosomes / Lysosomal Storage Diseases / Transient Expression / Proteolytic activity
Functional Characterization of Gne (UDP-N-Acetylglucosamine- 4-Epimerase), Wzz (Chain Length Determinant), and Wzy (O-Antigen Polymerase) of Yersinia enterocolitica Serotype O:8
Genetics / Bacteriology / Biological Sciences / Lipopolysaccharide / Crystal structure / Escherichia coli / Enzyme / Gram-negative bacteria / Lipopolysaccharides / Active site / Site-directed Mutagenesis / Yersinia Enterocolitica / Escherichia coli / Enzyme / Gram-negative bacteria / Lipopolysaccharides / Active site / Site-directed Mutagenesis / Yersinia Enterocolitica
Detoxication of carcinogenic fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferase P1-1 variants and glutathione
Catalysis / Kinetics / Humans / Glutathione / Polycyclic Aromatic Hydrocarbon / Carcinogens / Polycyclic aromatic hydrocarbons (PAHs) / Active site / Genetic variation / Glutathione Transferase / Biological activity / Individual Difference / Structure activity Relationship / Epidemiologic Studies / Biochemistry and cell biology / Molecular Structure / Carcinogens / Polycyclic aromatic hydrocarbons (PAHs) / Active site / Genetic variation / Glutathione Transferase / Biological activity / Individual Difference / Structure activity Relationship / Epidemiologic Studies / Biochemistry and cell biology / Molecular Structure
Hydrogen peroxide sensitive biosensor based on plant peroxidases entrapped in Os-modified polypyrrole films
Materials Engineering / Analytical Chemistry / Tobacco / Cyclic Voltammetry / Peroxidase / Hydrogen Peroxide / Glassy Carbon / Active site / Hydrogen Peroxide / Glassy Carbon / Active site
Identification of Trp300 as an Important Residue for Escherichia Coli Leader Peptidase Activity
Kinetics / Membrane Proteins / Mutation / Escherichia coli / Tryptophan / Molecular cloning / Active site / Base Sequence / Site-directed Mutagenesis / *Hot Temperature / Biochemistry and cell biology / Molecular cloning / Active site / Base Sequence / Site-directed Mutagenesis / *Hot Temperature / Biochemistry and cell biology
Human Mitochondrial Manganese Superoxide Dismutase Polymorphic Variant Ile58Thr Reduces Activity by Destabilizing the Tetrameric Interface † , ‡
Biochemistry / Polymorphism / Electrochemistry / Oxidative Stress / Amyotrophic Lateral Sclerosis / Free Radical / Crystal structure / Humans / Temperature / Superoxide Dismutase / Phenotype / Enzyme / Body Temperature / Temperature Dependence / Active site / Thermal Stability / Oxidative Damage / Genetic variation / Enzyme activity / Protein Conformation / Elevated Temperature / Site-directed Mutagenesis / Nervous System Diseases / Biochemistry and cell biology / Molecular Structure / Melting Temperature / Molecular Sequence Data / Free Radical / Crystal structure / Humans / Temperature / Superoxide Dismutase / Phenotype / Enzyme / Body Temperature / Temperature Dependence / Active site / Thermal Stability / Oxidative Damage / Genetic variation / Enzyme activity / Protein Conformation / Elevated Temperature / Site-directed Mutagenesis / Nervous System Diseases / Biochemistry and cell biology / Molecular Structure / Melting Temperature / Molecular Sequence Data
Mechanism of phosphoryl transfer by nucleoside diphosphate kinase
Catalysis / Kinetics / Macromolecular X-Ray Crystallography / Phosphorus / Animals / Dictyostelium / Active site / Lysine / Nucleoside Diphosphate Kinase / Protein Conformation / Structure activity Relationship / Hydrogen-Ion Concentration / Asparagine / Site-directed Mutagenesis / Tyrosine / Biochemistry and cell biology / Adenosine Triphosphate / Dictyostelium / Active site / Lysine / Nucleoside Diphosphate Kinase / Protein Conformation / Structure activity Relationship / Hydrogen-Ion Concentration / Asparagine / Site-directed Mutagenesis / Tyrosine / Biochemistry and cell biology / Adenosine Triphosphate
Model Pumices Supported Metal Catalysts
Chemical Engineering / Catalysis / Kinetics / PHOTOELECTRON SPECTROSCOPY / Silica / Alkali Metals / Electronic properties / Active site / Binding Energy / Structural Properties / Alkali Metals / Electronic properties / Active site / Binding Energy / Structural Properties
Antifungal chitinases from Bacillus pumilus SG2: preliminary report
Technology / Biological Sciences / Domain Analysis / World / Bacteria / Antifungal Activity / Enzyme / Active site / Amino Acid Profile / Saline Soil / Cell Wall / Enzyme Assay / Ammonium Sulfate / Rhizoctonia solani / Antifungal Activity / Enzyme / Active site / Amino Acid Profile / Saline Soil / Cell Wall / Enzyme Assay / Ammonium Sulfate / Rhizoctonia solani
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